Exemplary embodiments of the present disclosure include systems and methods capable of imaging, manipulating, and analyzing tissue using light, including for example, coagulating and breaking the molecular bonds (e.g. cutting) tissue.

Embodiments of an apparatus and method for sealing and cutting of tissue during surgeries, especially in general, endoscopic, laparoscopic and robotic, are described. In one aspect, an apparatus comprises a laser system and a laser beam delivery unit. The laser system comprises a tissue cutting laser configured to emit a first laser beam to cut a tissue. The laser system also comprises a tissue sealing laser configured to emit a second laser beam to seal the tissue. The laser beam delivery unit is detachably coupled to the laser system and is configured to guide and direct the first and second laser beams to cut and seal the tissue.

A system includes a focus optic configured to converge an electromagnetic radiation (EMR) beam to a focal region located along an optical axis. The system also includes a detector configured to detect a signal radiation emanating from a predetermined location along the optical axis. The system additionally includes a controller configured to adjust a parameter of the EMR beam based in part on the signal radiation detected by the detector. The system also includes a window located a predetermined depth away from the focal region, between the focal region and the focus optic along the optical axis, wherein the window is configured to make contact with a surface of a tissue.

A system for surgical treatment, in particular endovenous laser treatment, includes a laser device and an application module, wherein the laser device comprises a laser light source having at least one first laser diode element and the application module is optically connectable or connected to the laser light source. The application module is designed as a flexurally flexible catheter having an optical waveguide which comprises an RFID chip with a parameter and/or release coding, wherein the laser device comprises a controlling means with an RFID transmitter and receiver unit for reading from and writing to the RFID chip. The controlling means is configured such that an activation of the laser light source ensues in response to the RFID receiver unit detecting a predetermined parameter and/or release coding, and a timestamp is stored on the RFID chip for the invalidating of the catheter.

A light processing apparatus includes a first non-linear crystal disk for transmitting a first beam of photons having a first frequency to a second beam of photons having the first frequency and a second frequency oscillating in polarization directions orthogonal to each other, the second frequency being a half of the first frequency. Further included is a waveplate for transmitting the second beam of photons to a third beam of photons by rotating polarization directions of the second beam of photons such that the photons of the first frequency and of the second frequency oscillate in the same polarization directions. A second non-linear crystal disk is configured to transmit the third beam of photons to a fourth beam of photons of the first frequency, the second frequency and a third frequency, the third frequency being approximate a third of the first frequency.

A surgical laser system (100) includes a first laser source (140A), a second laser source (140B), a beam combiner (142) and a laser probe (108). The first laser source is configured to output a first laser pulse train (144, 104A) comprising first laser pulses (146). The second laser source is configured to output a second laser pulse train (148, 104B) comprising second laser pulses (150). The beam combiner is configured to combine the first and second laser pulse trains and output a combined laser pulse train (152, 104) comprising the first and second laser pulses. The laser probe is optically coupled to an output of the beam combiner and is configured to discharge the combined laser pulse train.

A system includes a focus optic configured to converge an electromagnetic radiation (EMR) beam to a focal region located along an optical axis. The system also includes a detector configured to detect a signal radiation emanating from a predetermined location along the optical axis. The system additionally includes a controller configured to adjust a parameter of the EMR beam based in part on the signal radiation detected by the detector. The system also includes a window located a predetermined depth away from the focal region, between the focal region and the focus optic along the optical axis, wherein the window is configured to make contact with a surface of a tissue.

A scanning mechanism to scan a light source, such as a low-level laser, to create a desirable energy distribution on a treatment area. The light source may include multiple light beam generators, each having a different wavelength and each having a different energy distribution. The scanning mechanism can be programmable to scan in different patterns in accordance with a desired treatment.

Particular embodiments disclosed herein provide a surgical laser system comprising first laser source configured to emit a first laser beam with a first wavelength and a second laser source configured to emit a second laser beam with a second wavelength. The surgical laser system further comprises a first diffraction optical element (DOE) tuned to the first wavelength and a second DOE tuned to the second wavelength, wherein the first DOE is configured to diffract the first laser beam into one or more first diffracted beams at a diffraction angle and the second DOE is configured to diffract the second laser beam into one or more second diffracted beams at the same diffraction angle. The surgical laser system further comprises one or more beam splitters configured to reflect the one or more first diffracted beams and the one or more second diffracted beams onto a lens.

A system for monitoring an ablation procedure in a target tissue includes a first light source for delivering light to the target tissue to generate photoacoustic signals and a second light source for delivering light to the target tissue for ablation therapy. The system further includes a beam mixer for receiving light from the first and second light sources to create a combined light beam. An ablation catheter including a single optical fiber receives the combined light beam from the beam mixer, wherein the combined light beam is emitted from a tip of the ablation catheter to perform simultaneous ablation therapy and photoacoustic monitoring of the ablation procedure in the target tissue in real time.