This disclosure describes manufacturing of a device configured to guide bone and tissue regeneration for a bone defect. A method may include receiving a three-dimensional digital model or scan representing an anatomical feature to be repaired, generating a simulated membrane using the three-dimensional model, the simulated membrane being configured to cover the anatomical feature to be repaired, generating a digital two-dimensional flattened version of the simulated membrane, and generating code or instructions configured to cause a three-dimensional printer or milling device to produce a trimming guide that includes an opening corresponding to the flattened version of the simulated membrane and that further includes a cut-out configured to hold a premanufactured membrane. The trimming guide may be operative as a guide for marking or cutting the premanufactured membrane through the opening while the premanufactured membrane is held in the cut-out.

Methods and apparatus for planning and/or carrying out a total knee replacement surgical procedure on a knee of a leg of a patient are described. Anatomical data for the leg of the patient is obtained, which allows the femoral mechanical axis, the tibial mechanical axis and the joint line of the knee to be determined. A planned proximal tibial cut angle and a planned distal femoral cut angle are determined. A total knee replacement procedure is carried out on the knee of the patient, wherein a distal femoral cut is made using the planned distal femoral cut angle and a proximal tibial cut is made using the planned proximal tibial cut angle.

Devices, systems, and methods of the present disclosure are directed to generating three-dimensional surface representations of an anatomic structure such as a heart cavity. More specifically, a three-dimensional surface representation of the anatomic structure is constrained relative to one or more anchor portions corresponding to received input regarding the location of anatomic features of the anatomic structure. The resulting three-dimensional surface representation includes salient features of the anatomic structure and, therefore, can be useful as visualization tool during any of various different medical procedures, including, for example, cardiac ablation.

Methods and system for characterizing ligament properties using elastography are disclosed. An ultrasound system capable of performing shear wave elasticity imaging and/or supersonic shear imaging may retrieve one or more images from a proposed surgical site. The one or more images may be provided to a surgical planning system that identifies one or more properties of ligaments proximate to the surgical site. Musculoskeletal simulations may be performed using the identified properties to preoperatively identify a surgical plan. Preoperative identification of a surgical plan may enable a surgeon to select from more fine-tuning options for a joint replacement than conventional systems.

Systems and methods for controlling vibrations of an ultrasonic handpiece generate an AC drive signal applied to a transducer of the ultrasonic handpiece to vibrate a tip of the ultrasonic handpiece. A property relating to a stiffness of tissue being contacted by the vibrating tip is determined based on a measured voltage and a measured current of the AC drive signal. A target displacement for the tip is determined based on the tissue property, and the AC drive signal is adjusted to achieve the determined target displacement.

A tissue suturing guidance system includes an image capturing device, a display, and a processor in communication with the image capturing device and the display. The image capturing device is configured to capture a suture site. The display is configured to display an image of the suture site. The processor is configured to: determine, based on the image of the suture site, a geometric tissue representation of the suture site; access measured properties of the suture site; determine, based on the measured properties of the suture site, a biomechanical tissue representation of the suture site; and generate, based on the geometric tissue representation and biomechanical tissue representation of the suture site, a suturing configuration for the suture site.

Disclosed are an automatic planning method and a device for tissue ablation. The method includes: obtaining a three dimensional (3D) model of a to-be-ablated tissue through a 3D reconstruction technique; marking a cylindrical ablation point on the 3D model through an ablation planning, an axial direction of the ablation point is the same as a radio frequency direction of thermal ablation; and displaying an ablated area on the 3D model, the reconstruction technique includes: obtaining slice images of the to-be-ablated tissue in a plurality of directions, the slice image in each direction includes a plurality of two dimensional (2D) images; depicting, by a primitive, the to-be-ablated tissue on the 2D images in one direction; and constructing the 3D model of the to-be-ablated tissue through the 3D reconstruction technique based on the original 2D images.

The present invention provides a method for generating a bone fixation implant and related preoperative planning. The method comprises a first step of determining at least the orientation and the position of the fixation means, based on a 3D model of the bone fragments. The method may include a second step of defining the shape of one or more bone plates, based on the output of the first step. The method may further include a third step determining tools for applying fixation means during surgery, according the optimized configuration defined in the first step and applying the bone plates from the second step. The method may even further include a fourth step, quantifying construct stability for a given patient following surgery, thereby allowing early weightbearing.

Improvements to devices, systems, and methods for delivering and/or deploying an implantable medical device are described. An implantable medical device may include an annuloplasty ring for implantation on a valve of a patient. Systems and methods may be configured to present graphical user interfaces with device images to implement efficient and accurate implantation of the implantable medical device. The device images may be based on sensor information obtained via sensors associated with the implantable medical device, such as a camera device, a diagnostic imaging device, position sensors, and/or the like. In other aspects, systems and methods may determine optimized configurations for the implantable medical device based on device characteristics including, without limitation, a shape formed by components of the implantable medical device and/or component coordinate information. Systems and methods may operate to facilitate deployment of the implantable medical device to correspond with the optimized configuration. Other embodiments are described.

Augmented and/or mixed reality systems for performing various types of arthroplasty are provided, along with methods of performing various types of arthroplasty using such augmented reality systems. More particularly, the augmented and/or mixed reality system and method is used to achieve accurate bone preparation, implant placement and orientation, and biomechanical restoration in orthopaedic arthroplasty procedures. Preparation, implantation, and adjustment of arthroplasty surgical sites, prosthetic components, and tailoring and positioning of installed prosthetic components can be guided using augmented reality overlays, projections, or combined imaging of a surgeon's real-world view.