Methods and systems of computing parameter values of one or more model parameters are described. The model models structural and dielectric properties of a structure in a human or an animal body. An exemplary method includes: accessing voltage measurements made at different places in the vicinity of the structure by one or more in-body field sensing electrodes in response to currents applied to one or more field supplying electrodes; and computing the parameter values by adjusting the parameter values to fit predicted voltage values to the accessed voltage measurements, wherein the predicted voltage values are predicted from the model for the currents applied to the field supplying in-body electrodes.

A guidance device is disclosed. The device may comprise a tracking pad with a guiding opening and a plurality of sensors operable with at least one beacon on a needle to track the disposition of the needle at least when a distal end of the needle is inserted into the guiding opening. Related systems and methods are also disclosed.

An electroporation ablation system includes a probe to be inserted into a body part of a living subject, and including a distal end including at least one electrode, body-surface patches to be applied to a skin surface, an ablation power generator to apply at least one first electrical pulse train between the electrode(s) and first one(s) of the body-surface patches, and a processor to provide a measurement of movement of the living subject responsively to applying the first electrical pulse train(s) between the electrode(s) and the first one(s) of the body-surface patches, and select second one(s) of the body-surface patches responsively to the measurement of movement, and wherein the ablation power generator is configured to apply at least one second electrical pulse train between the electrode(s) and the second one(s) of the body-surface patches.

Electrical field-guided positioning of a second device within a body cavity, using electrical field mapping information generated from electrical field measurements by electrodes of a first device. The first device, in some embodiments, is a catheter electrode probe, and the second device is an internally implantable and/or operated medical device. An exposed, electrically conductive portion of the second device is optionally configured to be used as an electrical field measuring electrode. A rule is applied to measurements made by this electrode to estimate its position within a body cavity. The rule is generated, in some embodiments, using measurements made by the first device.

Disclosed herein are techniques for implementing an intelligent assistance (“IA”) or extended intelligence (“EI”) ecosystem for soft tissue luminal applications. In various embodiments, a computing system analyzes first layer input data (indicating movement, position, and/or relative distance for a person(s) and object(s) in a room) and second layer input data. The second layer input data includes sensor and/or imaging data of a patient. Based on the analysis, the computing system generates one or more recommendations for guiding a medical professional in navigating a surgical device(s) with respect to one or more soft tissue luminal portions of the patient. The recommendation(s) include at least one mapped guide toward, in, and/or around the one or more soft tissue luminal portions. The mapped guide can include data corresponding to at least three dimensions, e.g., a 3D image/video. The computing system can present the recommendation(s) as image-based output, using a user experience device.

In general, devices, systems, and methods for fiducial identification and tracking are provided.

The present disclosure is directed to measuring impedance across a plurality of electrode pairs. The disclosed systems and methods may simultaneously provide drive signals between electrode pairs and then sense the voltage signals that develop at the electrodes. Digital signal processing may be used to synchronously demodulate the voltage signal at each electrode to determine impedances at the electrodes. Each electrode pair may be driven at a unique frequency to allow for significantly increasing a number of electrode pairs and/or increasing drive current magnitudes. Synchronous demodulation allows the unique frequencies to be detected independent of each other while minimizing crosstalk. Typically, the drive frequencies are made orthogonal by setting the drive frequencies at harmonics of a common base frequency and measuring a response over an integer number of cycles. In an embodiment, quadrature demodulation may occur providing a real component for resistive impedance and an imaginary component for reactive impedance.

The navigation systems and methods facilitate aligning a tool in relation to a trajectory in real-time to receive input data from a pre-operative plan image, at least one multi-modal image, and at least one real-time multi-modal image; interactively track at least one neural fiber, whereby interactively tracked fiber data is obtainable; automatically generate output data by way of data transformation using the input data and the interactively tracked neural fiber data; and transmit the output data to at least one of: at least one display device for rendering at least one real-time interactive navigation display for facilitating neural navigation, and at least one drive device for positioning at least one tracking device in relation to the tool in real-time, whereby real-time alignment data is achievable, and whereby at least one neurological structure is preservable.

A method includes, in a processor, receiving signals from (i) a first position sensor disposed on a shaft of a catheter, and (ii) a second position sensor disposed on a distal end of a sheath of the catheter. Based on the signals received from the first position sensor and the second position sensor, an event is detected in which an expandable distal-end assembly of the catheter is being withdrawn into the sheath while still at least partially expanded. A responsive action is initiated in response to detecting the event.

A system for differentiating between magnetic field distortion and physical movement in a hybrid magnetic and impedance tracking system can comprise a first drive patch and a second drive patch configured to generate an electrical field within the body for locating an electrode on the medical device, a magnetic localization system configured to generate a magnetic field, a magnetic sensor configured to receive signals from the magnetic localization system, and an electronic control unit configured to receive location data from the impedance localization system and magnetic sensor location data from the magnetic localization system. The electronic control circuit can be configured to detect a location change of the magnetic sensor and use the drive patch location data and magnetic sensor location data to determine whether the detected location change of the magnetic sensor is caused by a magnetic field distortion or a physical movement of the magnetic sensor.