A tissue implantation device comprises a capsule; and a population of ultrasound-switchable fluorophores incorporated in the capsule. A method of imaging a tissue implantation device in a biological environment comprises disposing the tissue implantation device in a biological environment, the population of ultrasound-switchable fluorophores having a switching threshold in the biological environment; exposing the biological environment to an ultrasound beam to form an activation region within the biological environment; switching the ultrasound-switchable fluorophores in the activation region from an off state to an on state; exciting the ultrasound-switchable fluorophores in the activation region with a beam of electromagnetic radiation; and detecting light emitted by the ultrasound-switchable fluorophores.

A holographic augmented reality ultrasound needle guide system and method includes an augmented reality display such as a headset wearable by a user. The augmented reality display is configured to depict a virtual ultrasound image. The augmented reality display is further configured to allow a user to select a desired reference point on the virtual ultrasound image. The system is configured to depict a holographic needle guide based on the selection of the desired reference point. The system is also configured to adjust a trajectory of the holographic needle guide to avoid intersecting undesired anatomical structures. The augmented reality display is further configured to stamp the holographic needle guide into a selectively locked trajectory and position.

An apparatus for aiding the removal of cataracts in which an optical fiber delivers sufficient optical energy of the correct wavelength, pulse duration to achieve controlled non-thermal and non-acoustic dissolution of hard cataract tissue.

Tip confirmation systems and related methods are disclosed. A method of determining one or more properties of a catheter in a patient comprises advancing a catheter in vasculature of a patient, the catheter coupled to at least one radiation source and at least one detector, transmitting source electromagnetic radiation from the at least one radiation source out of the catheter proximate a distal tip thereof, measuring an intensity of backscattered electromagnetic radiation from the at least one radiation source with the at least one detector, and providing a signal indicative of a location of the distal tip within the vasculature based, at least in part, on the measured intensity of the backscattered electromagnetic radiation. Related systems and methods are also disclosed.

An indwelling clip includes a clip main body having a pair of arm plate portions that can be opened in a substantially V shape with an elastic force and claw portions formed on respective tip portions of the arm plate portions. The indwelling clip also includes a fastening ring attached to the arm plate portions so as to be movable along a longitudinal direction of the pair of arm plate portions and be able to close the pair of arm plate portions by moving in a direction of the claw portions. An outer surface of the claw portion is provided with a fluorescent body containing a fluorescent pigment emitting red or near infrared light by being irradiated with excitation light.

Some embodiments of the present technology involve methods, devices, and systems for determining an orientation of a surgical tool during ophthalmic surgery. An example method includes performing an optical imaging scan in the surgical site, using a scan pattern that intersects the surgical tool and generating a scan image from the optical imaging scan. The example method further comprises analyzing the scan image to determine a location in the scan image corresponding to where the surgical tool intersected the optical imaging scan, and determining an orientation of the surgical tool, based on the determined location.

Systems and methods for resecting a knee joint using a navigated pin guide driver system. The navigated pin guide driver system communicates with a navigation system to aid a user in placing cut block pins into the knee joint. The navigated pin guide driver system may include a handle, a reference element that electronically communicates with the navigation system, one or more pin guide tubes that may correspond to one or more cut blocks, and a distal tip that is configured to attach to the bone.

An indwelling clip includes a pair of arm plate portions that can be opened in a substantially V shape with an elastic force and claw portions formed on respective tip portions of the arm plate portions. The indwelling clip also includes a fastening ring attached to the arm plate portions so as to be movable along a longitudinal direction of the pair of arm plate portions and be able to close the pair of arm plate portions by moving in a direction toward the claw portions. The arm plate portion is provided with a fluorescent body containing a fluorescent pigment emitting red or near infrared light by being irradiated with excitation light. According to some embodiments, the indwelling clip allows easy visual recognition of light emission of a fluorescent body from the outside of a hollow organ and enables excellent attachment stability to the inner wall of the hollow organ.

A medical robot system, including a robot coupled to an effectuator element with the robot configured for controlled movement and positioning. The system may include a transmitter configured to emit one or more signals, and the transmitter is coupled to an instrument coupled to the effectuator element. The system may further include a motor assembly coupled to the robot and a plurality of receivers configured to receive the one or more signals emitted by the transmitter. A control unit is coupled to the motor assembly and the plurality of receivers, and the control unit is configured to supply one or more instruction signals to the motor assembly. The instruction signals can be configured to cause the motor assembly to selectively move the effectuator element and is further configured to (i) calculate a position of the at least one transmitter by analysis of the signals received by the plurality of receivers; (ii) display the position of the at least one transmitter with respect to the body of the patient; and (iii) selectively control actuation of the motor assembly in response to the signals received by the plurality of receivers.

Presented herein are systems, methods, and architectures related to augmented reality (AR) surgical visualization of one or more dual-modality probe species in tissue. As described herein, near infrared (NIR) images are detected and rendered in real time. The NIR images are registered and/or overlaid with one or more radiological images (e.g., which were obtained preoperatively/perioperatively) by a processor [e.g., that uses an artificial neural network (ANN) or convolutional neural network (CNN) reconstruction algorithm] to produce a real-time AR overlay (3D representation). The AR overlay is displayed to a surgeon in real time. Additionally, a dynamic motion tracker tracks the location of fiducial tracking sensors on/in/about the subject, and this information is also used by the processor in producing (e.g., positionally adjusting) the AR overlay. The real-time AR overlay can improve surgery outcomes, for example, by providing additional real-time information about a surgical site via an intuitive visual interface.