A multi-lumen implantable device configured to deliver a therapeutic agent to a selected portion of a blood vessel is disclosed. As one example, an implantable device includes a first lumen configured to flow blood from an upstream end to a downstream end of the device when implanted in a blood vessel; a second lumen fluidly separated from the first lumen and configured for introducing a therapeutic agent to a selected, first portion of a wall of the blood vessel, between the upstream end and the downstream end of the device; and at least one sealing member configured to block the therapeutic agent from entering a second portion of the wall of the blood vessel, between the upstream end and the downstream end of the device.

A vascular shunt stent includes a main body tube and at least one branch tube axially inserted into an inner lumen of the main body tube. The main body tube includes a tubular main membrane. At least one branch tube includes a tubular branch membrane, which is accommodated in an inner lumen of the main membrane. A first sealing film is arranged between a distal end of the main membrane and a distal end of the branch membrane to separate the inner lumen of the main membrane into a main opening and at least one first sub-opening, the first sub-opening is in sealed connection with the distal end of the branch membrane. An included angle between a plane defined by the first sub-opening is not parallel with a plane defined by the main opening.

Provided is a segmented covered stent (100), which includes a covering membrane (120) and a support frame (110) fixed to the covering membrane (120). The support frame (110) comprises an annular structure (1200) and a spiral structure (1300), wherein the annular structure (1200) is formed by a plurality of first wave-shaped units (1100) connected end to end; and the spiral structure (1300) is a tubular structure formed by a plurality of second wave-shaped units (1400) connected end to end and arranged in a continuous spiral manner, and the overall extension direction of the spiral structure (1300) is parallel to the support frame (110). A method for preparing the segmented covered stent (100) is further provided.

A luminal stent includes a tube body that can be compressed and expanded in the radial direction, and an anti-leakage structure. The tube body is divided by the anti-leakage structure into a first tube body positioned on one side of the anti-leakage structure, and a second tube body positioned on the other side of the anti-leakage structure, with at least part of the first tube body being encircled by the anti-leakage structure. In a compressed state, the maximum compression diameter of the anti-leakage structure and the first tube body encircled by the anti-leakage structure is greater than or equal to the maximum compression diameter of the second tube body.

A stent graft for treating an arterial aneurysm includes a ligature traversing at least a portion of struts of stents, the ligature having ends that, when linked, at least partially constrict a radial dimension of the stents. The ends of the ligature can be linked by a wire in a stent graft delivery system that threads anchor loops longitudinally spanning ends of the ligature to maintain the stent in a radially constricted position during delivery to the aneurysm. The stent graft can be implanted at the aneurysm by retracting the wire from the linked ends of the ligature and from the anchor loops, thereby releasing the associated stent from the radially constricted position.

A polymer coating/ring is employed to aid in the sealing and connection of modular elements used in body flow lumens for the exclusion and bypass of diseased regions of the flow lumen, such as where aneurysm occurs adjacent to branching blood vessels.

A stent graft for treating an arterial aneurysm includes a ligature traversing at least a portion of struts of stents, the ligature having ends that, when linked, at least partially constrict a radial dimension of the stents. The ends of the ligature can be linked by a wire in a stent graft delivery system that threads anchor loops longitudinally spanning ends of the ligature to maintain the stent in a radially constricted position during delivery to the aneurysm. The stent graft can be implanted at the aneurysm by retracting the wire from the linked ends of the ligature and from the anchor loops, thereby releasing the associated stent from the radially constricted position.

Universal endovascular grafts are provided for evaluation and repair of damaged or aneurismal blood vessels. More particularly, the present invention relates to universal fenestrated and universal branched endografts for repair of blood vessels with branches, methods for implanting the endografts in the vessel and for making connection with one or more branches. The universal fenestrated endografts have a body with a first end, a second end, a first wall, a second wall, and an interior passage or lumen. The body further includes openings in communication with the passage at the first and second ends and one or more lateral fenestrations in communication with the lumen. The body further has a necked portion between the ends and a cannulation member. The universal branched endografts have a tubular body with a main lumen and four branch lumens. A large branch extends from the body. The four lumens are positioned about a circumference of the tubular body.

Devices, systems, and methods for implanting a patient-specific prosthesis at a treatment site in a patient are disclosed herein. In some embodiments, a patient-specific prosthesis includes a tubular graft and a coupling member. A fenestration can be disposed in the tubular graft, the fenestration corresponding to a predicted branch blood vessel location. The coupling member can be disposed about the fenestration. The coupling member can include a coil configured to expand from a first configuration to a second configuration in response to the application of an expanding force. The coil can be configured to contract to a third configuration upon removal of the expanding force.

The stent graft includes a main body and an external coupling. The main body extends along a longitudinal axis and includes proximal and distal ends. The external coupling extends away from the main body and defines an opening having a center. The main body includes a first bracketing stent extending about a proximal side of the external coupling. The first bracketing stent includes first and second peaks. The first peak is circumferentially aligned with the center of the external coupling. The first peak is proximal the second peak about the main body along the longitudinal axis.