The invention relates to an artificial vascular graft comprising a primary scaffold structure encompassing an inner space of the artificial vascular graft, said primary scaffold structure having an inner surface facing towards said inner space and an outer surface facing away from said inner space, a coating on said inner surface, wherein a plurality of grooves is comprised in said coating of said inner surface. The primary scaffold structure comprises further a coating on said outer surface. The primary scaffold structure and the coating on said inner surface and on said outer surface are d designed in such a way that cells, in particular progenitor cells, can migrate from the periphery of said artificial vascular graft through said outer surface of said coating, said primary scaffold structure and said inner surface to said inner space, if the artificial vascular graft is used as intended. The invention relates further to a method for providing said graft.

System for assisting vascular fluid flow body comprising: Fluid pump having an inlet for fluid in the vascular system to enter and an outlet for discharging pumped fluid into the vascular system at a fluid pump outlet pressure. Occluder placed into the vascular system at a location downstream of the outlet of the fluid pump. Occluder having a configuration in which the occluder occludes the vascular system and a configuration in which pumped is capable of flowing past the occluder. In use, the occluder being actuatable to alternate between the occluded configuration, in which pumped fluid accumulates in the vascular system becoming increasingly under pressure via elastic deformation of vessels, and the flow configuration, in which accumulated pumped fluid under pressure flows past the occluder at a greater pressure than the fluid pump outlet pressure, returning the elastically deformed vessels towards their original state.

A kit of stents and an adjustable multi-lumen stent for adjustable interventional reduction of blood flow in a blood vessel. The kit includes: a first reduction stent having in an expanded conformation at least one widened section and a narrowed section, the narrowed section defining a central lumen providing reduced fluid communication between an upstream end and a downstream end of the first reduction stent; at least one expandable dilatation stent having a tubular form insertable into and expandable in the central lumen of the first reduction stent to define an enlarged central lumen; at least one second reduction stent having a narrowed tubular section insertable into the central lumen of the first reduction stent or the central lumen of the dilatation stent to define an reduced central lumen, and having an anchoring element at its upstream end.

An implantable medical device includes an elongate member having a cross-sectional dimension that is less than 0.00085 inch, wherein the elongate member is made from a material comprising a platinum-tungsten alloy having a percentage of tungsten that is at least 10% by weight or alternatively the implantable medical device includes an elongate member made from a material comprising an alloy containing rhenium.

Methods and devices for increasing flow in the left atrial appendage (LAA) include a conduit directing blood flow from a pulmonary artery into the LAA and/or a conduit drawing blood from the LAA by a Bernoulli effect. In one embodiment, a method comprises implanting a conduit in a pulmonary vein, expanding an inlet portion such that the conduit becomes anchored within the vein and directs blood through an outlet portion of the conduit into or toward the left atrial appendage.

Devices, systems and methods for filtering embolic particles that may be generated from a medical procedure including protection of the major branching vessels from the aorta, and catches and filters emboli that may be generated during the TAVR procedure. The filter devices disclosed herein form an improved seal against the vessel wall that is activated by flowing blood. Devices described herein also allow for the closing of the ends of the filter device after capture of emboli, providing further security against accidental loss of emboli post capture.

An implantable flow adjuster (20) includes proximal and distal support rings (22, 24) which support a flow adjuster panel (26). The flow adjuster panel (26) divides the lumen through the device (20) into two sections, one of reducing cross sectional area and the other of increasing of increasing cross sectional area. The two sections (40, 42) cause, respectively, an increase in blood pressure and blood flow and a decrease in blood pressure and blood flow. These result is a pressure differential beyond the distal end of the device (20). This pressure differential can be used to divert blood flow away from the neck (14) into an aneurysm (12), thus to reduce pressure and wall sheer stress within the aneurysm in order to assist in the repair of the vessel.

The acute and chronic devices and methods described herein include a body lumen fluid flow modulator including an upstream flow accelerator and a downstream flow decelerator. The fluid flow modulator preferably includes one or more openings that define a gap/entrainment region that provides a pathway through which additional fluid from a branch lumen(s) is entrained into the fluid stream flowing from the upstream flow accelerator to the downstream flow decelerator. Delivery devices including a sheath and inner assembly also are provided for delivering the flow modulator to the body lumen. The delivery device may maintain the flow modulator in its collapsed, delivery state upon retraction of the sheath for ease of readjustment within the body lumen prior to full deployment of the flow modulator within the body lumen.

The invention relates to generally to a vascular access graft that includes a magnetic element disposed about a flow tube for guiding a blood flow between an arterial end adapted for arterial anastomosis to a portion of an artery, and a venous end adapted for venous anastomosis to a portion of a vein. The magnetic element may include a plurality of magnets disposed about the flow tube so that a magnetic field may be applied to blood flowing therein; the magnetic element may alternatively include a circuitry configured to generate a magnetic field applied to the flow tube.

A temporary, removable mechanical circulatory support heart-assist device has at least two propellers or impellers. Each propeller or impeller has a number of blades arranged around an axis of rotation. The blades are configured to pump blood. The two propellers or impellers rotate in opposite directions from each other. The device can be configured to be implanted and removed with minimally invasive surgery.