The present invention provides compositions and methods for attaching tendon to bone. The present invention provides compositions and methods for treating rotator cuff injuries. In one embodiment, a method for treating rotator cuff injuries comprises providing a composition comprising PDGF disposed in a biocompatible matrix and applying the composition to at least one site of tendon reattachment on the humeral head.

The present invention provides compositions and methods for attaching tendon to bone. The present invention provides compositions and methods for treating rotator cuff injuries. In one embodiment, a method for treating rotator cuff injuries comprises providing a composition comprising PDGF disposed in a biocompatible matrix and applying the composition to at least one site of tendon reattachment on the humeral head.

Systems and methods for fixating a graft in a bone tunnel are provided. In general, the system includes a tissue fixation device having a delivery configuration and a deployed configuration, at least one graft retention loop coupled to the tissue fixation device, and a drill pin having a sidewall surrounding a cavity at a proximal end of the pin and at least one longitudinally oriented opening in the sidewall in communication with the cavity, the cavity being configured to fully seat the tissue fixation device. The drill pin is configured to substantially contain therein the tissue fixation device when in the delivery configuration and to enable deployment of the tissue fixation device through the opening. Drill pins configured to contain a tissue fixation device are also provided.

The improved endoprosthetic device surface treatment encourages soft tissue attachment thereto. A porous mesh surface treatment creates on an outer surface of the endoprosthetic device a three-dimensional surface structure similar to cancellous bone. Suture attachment features are provided at various locations around the treated surface structure to initially affix a vascularized soft tissue to the treated surface. As the patient heals the soft tissue grows and infiltrates the porous mesh surface to achieve an attachment strength substantially equal to the surrounding tissue.

Described herein are methods and apparatuses (e.g., systems and devices, including tools) for delivering and securing grafts in a patient's body, especially connective tissue-to-bone interface grafts for repair of the enthesis, including ligament to bone and tendon to bone interface scaffolds for repair of torn tendons, ligaments, and/or calcified and uncalcified fibrocartilage.

Systems and methods for fixating a graft in a bone tunnel are provided. In general, the system includes a tissue fixation device having a delivery configuration and a deployed configuration, at least one graft retention loop coupled to the tissue fixation device, and a drill pin having a sidewall surrounding a cavity at a proximal end of the pin and at least one longitudinally oriented opening in the sidewall in communication with the cavity, the cavity being configured to fully seat the tissue fixation device. The drill pin is configured to substantially contain therein the tissue fixation device when in the delivery configuration and to enable deployment of the tissue fixation device through the opening. Drill pins configured to contain a tissue fixation device are also provided.

The disclosure describes implantable medical products, that include dry or partially hydrated biocompatible constructs comprising collagen fibers configured to expand in situ after implantation to frictionally engage a bone tunnel wall to thereby affix the construct in the bone tunnel.

An improved modular rotational device includes a first and second threaded coupler for affixation along the stem of an endoprosthetic device, for example, a humeral prosthesis or a femoral prosthesis. The rotational device axis of rotation is coaxial with the stem, and its axis of rotation is located in close proximity to the intramedullary stem of the prosthesis or in close proximity to the distal articulation of the prosthesis. A housing has a proximal and distal end with an axial bore therethrough for receiving an elongated stem of the device. A lobe ring may be utilized to limit the axis of rotation of the device. Additional endoprosthetic devices may be attached to male or female threaded couplers, or to Morse tapers. A plurality of suture attachments facilitates attachment of soft tissue thereto.

The disclosure describes implantable medical products, that include dry or partially hydrated biocompatible constructs comprising collagen fibers configured to expand in situ after implantation to frictionally engage a bone tunnel wall to thereby affix the construct in the bone tunnel.

The present invention provides compositions and methods for attaching tendon to bone. The present invention provides compositions and methods for treating rotator cuff injuries. In one embodiment, a method for treating rotator cuff injuries comprises providing a composition comprising PDGF disposed in a biocompatible matrix and applying the composition to at least one site of tendon reattachment on the humeral head.