An accommodative intraocular lens capable of effectively exerting a focus adjustment function includes an optical portion and a plurality of support portions arranged around the optical portion. The support portion includes an anterior support portion and a posterior support portion, and the anterior support portion presses an anterior capsule and the posterior support portion presses a posterior capsule by the elastic force of the support portion. When the lens capsule is in a distance vision state or in a near vision state, as the pressing force of the anterior capsule against the anterior support portion increases or decreases, the anterior support portion deflects backward or returns forward while maintaining the radial position of the base end portion, so that the tip end portion of the anterior support portion moves backward or forward greatly while maintaining the radial position, and the optical portion moves backward or forward accordingly.

An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.

A system for delivering an intraocular lens (IOL) is disclosed, including: a handpiece including a barrel defining an elongate passage, a pushrod disposed inside the elongate passage, and a plunger coupled to the pushrod; and a delivery unit coupled to a first end of the barrel, the delivery unit including a delivery tube and a lens holder coupled to the delivery tube, the lens holder including a lead haptic shelf arranged to receive a lead haptic of an IOL that is contained inside the lens holder, wherein the lead haptic shelf is configured to fold the lead haptic of the IOL over a body of the IOL while permitting the IOL to travel under the lead haptic shelf when the IOL is displaced from the lens holder to the delivery tube by the pushrod during delivery of the IOL into a patient's eye.

The present disclosure provides an ophthalmic lens that is disposed to balance coma aberrations if the lens, when inserted in a patient's eye, is decentered or tilted with respect to an optical axis of the patient's eye, and maintain a substantially diffraction-limited image quality if the lens, when inserted in the patient's eye, is centered with respect to the optical axis of the patient's eye. The lens may include an optic having an anterior surface and an opposing posterior surface disposed about an optical axis of the lens. One of the surfaces (e.g., the anterior surface) may have a semi-aspheric surface profile, which includes an inner region having a substantially spherical surface profile and extending radially from the optical axis of the lens to a first boundary, and an outer region having an aspherical surface profile and extending radially at least beyond the first boundary to a second boundary.

To provide an intraocular lens to which a mark for assisting more accurate fixation in an eye has been applied. Provided is an intraocular lens including an optical part having a mark that is detectable under illumination of a specific wavelength range outside a wavelength range of visible light, and a support part that supports the optical part, in which the mark is indicated by a geometric pattern that allows for identification of an optical center position of the optical part and information regarding posture of the optical part in an eye.

An accommodating intraocular lens device for treatment of an eye having a lens body; internal support; stabilization system; and force translation arm. The lens body includes an accommodating membrane, an annular element, a static element, and a fixed volume of optical fluid filling a sealed chamber of the lens body. The annular element coupled to the perimeter of the accommodating membrane has a shape deformation membrane configured to undergo displacement relative to the perimeter region. The sealed chamber is formed by inner surfaces of the accommodating membrane, shape deformation membrane, and static element. The force translation arm has a first end operatively coupled to the shape deformation membrane and a free end available and configured to engage a ciliary structure of the eye. The force translation arm is moveable relative to the lens body to cause inward movement of the shape deformation membrane. Related methods, devices, and systems are provided.

Intraocular lenses for reducing the risk of posterior capsule opacification (PCO) are described herein. PCO can be reduced with an IOL design that increases the pressure at the posterior capsular bend, for example, by including a sharper edge design, an enlarged optical zone, and/or an increased vault height. An example ophthalmic lens can include an optic (200) including an anterior surface (202) defining an anterior side of the optic, a posterior surface (204) defining a posterior side of the optic, and an edge (210) arranged between the anterior and posterior surfaces. The edge and the posterior surface can form an angle, where the angle is less than about 90 degrees. Additionally, the ophthalmic lens can have an increased vault height. At least one of the angle or the increased vault height be configured to increase pressure on a capsular bend in a subject's eye.

Embodiments disclosed herein relate to systems and methods for securing a drug delivery component to an intraocular lens (IOL) assembly. The systems generally include a support base and a plunger. The support base includes a first portion configured to accommodate a drug delivery component; and a second portion configured to act as a plunger guide. The plunger can be inserted into the plunger guide such that the plunger is positioned to interface with a drug delivery component and an IOL assembly during use. The plunger includes an elongated body and a tip, wherein the tip can include a ramp configured to interface with a fixation loop of a drug delivery component during use and a compartment configured to interface with a haptic of an IOL assembly during use.

Embodiments disclosed herein generally relate to a stabilized intraocular drug delivery system for implantation into an eye of a subject. The system can include an intraocular lens (IOL) assembly and a drug delivery component. The IOL assembly can include a lens and a haptic. The haptic can include an outer end, an inner end opposite the outer end, a retention tab at the inner end, and a connection tab positioned between the outer end and the inner end and adjoining the lens. The drug delivery component can include at least one therapeutic agent and a fixation portion having an opening to receive the haptic and secure the drug delivery component to the IOL assembly. The fixation portion of the drug delivery component can be secured to the connection tab of the haptic such that the retention tab inhibits movement of the drug delivery component relative to the IOL assembly.

Intraocular lens and methods for optimization of depth of focus and the image quality in the periphery of the visual field. The intraocular lens (600) comprises a central part and a peripheral part, the central part being the optical part (600) and the peripheral part comprising mechanical fasteners (603), and the central part comprises: an aspherical concave anterior surface (601), which is the surface closest to the iris of the eye once the lens (600) has been implanted in the eye, and an aspherical convex posterior surface (602), which is the surface closest to the retina of the eye once the lens (600) has been implanted in the eye, such that the radius of curvature of the posterior surface (602) of the central part is smaller than the radius of curvature of the anterior surface (601) of the central part, with a ratio between radii of between 2 and 6, and the mechanical fasteners (603) are arranged at an angle (605) of between 0° and 10° with respect to a plane passing through the joints between the central part and the peripheral part and which is perpendicular to the optical axis of the eye in which the lens (600) is intended to be implanted.