Described are polymerizable high energy light absorbing compounds of formula I:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, and X are as described herein. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

A multi-piece IOL assembly is provided that includes a platform and an optic. The platform has an inner periphery surrounding an inner zone of the platform. The optic has an optical zone, an outer periphery and a retention mechanism disposed on the outer periphery. The optic is configured to be disposed in the inner zone of the platform and to extend to a location between the inner periphery and the outer periphery of the platform to be secured to the platform at the location. The platform can be secured to an inner periphery of the eye or can be formed into a natural lens by cutting the lens using a laser or other energy source.

Artificial lenses and methods for optimizing vision in an eye of a patient comprising the steps of determining a target optical configuration including the optimum defocus and aberrations that the patients' eye should have in order to match or approximate the original optical configuration of the patient; determining the refractive change of the patient's eye required to achieve the optical configuration best corresponding to target optical configuration for the patient; and implementing the selected refractive change to achieve the target optical configuration.

A bioanalogic implantable ophthalmic lens (BIOL) capable of replacing the natural crystalline lens (NCL) in its various essential functions after the NCL having been removed and BIOL implanted into the posterior eye chamber and placed into the capsular bag vacated from the NCL. At least the posterior surface of the lens has a convex shape and is made from a transparent flexible hydrogel material. At least the anterior and posterior optical surfaces are defined by rotation of one or more conic sections along the main optical axis and the surfaces defined by the rotation will include a plane perpendicular to the axis and conical surface symmetrical by the axis. A hydrogel implantable ophthalmic lens whose optical parameters can be optimized and/or customized by a controlled absorption of electromagnetic radiation resulting in a change of the refractive index of the irradiated hydrogel.

The invention relates to novel optical elements having improved UV protection. The optical element comprises a light adjustable optical element with a UV absorbent layer applied to at least one surface of the optical element. The invention is particularly useful in light adjustable intraocular lenses.

Disclosed are high refractive index, hydrophobic, acrylic materials. These materials have both high refractive index and a high Abbe number. This combination means the materials have a low refractive index dispersion and thus are especially suitable for use as intraocular lens materials. The materials are also suitable for use in other implantable ophthalmic devices, such as keratoprostheses, corneal rings, corneal implants, and corneal inlays.

Method, product and blocking element of short wavelengths in LED-type light sources consisting of a substrate with a pigment distributed on its surface and, in that said pigment has an optical density such that it allows the selective absorption of short wavelengths between 380 nm and 500 nm in a range between 1 and 99%.

A bioanalogic implantable ophthalmic lens (BIOL) capable of replacing the natural crystalline lens (NCL) in its various essential functions after the NCL having been removed and BIOL implanted into the posterior eye chamber and placed into the capsular bag vacated from the NCL. At least the posterior surface of the lens has a convex shape and is made from a transparent flexible hydrogel material. At least the anterior and posterior optical surfaces are defined by rotation of one or more conic sections along the main optical axis and the surfaces defined by the rotation will include a plane perpendicular to the axis and conical surface symmetrical by the axis. A hydrogel implantable ophthalmic lens whose optical parameters can be optimized and/or customized by a controlled absorption of electromagnetic radiation resulting in a change of the refractive index of the irradiated hydrogel.

A color-apodized intraocular lens includes a lens center, with a center-transmittance to transmit an incident light; a lens annul us, surrounding the lens center, configured to selectively attenuate the incident light according to a radius- and wavelength-dependent annulus-transmittance, wherein the annulus-transmittance is less than the center-transmittance, in a short wavelength spectral range; and haptics, extending from the lens annulus. A method of making a color-apodized intraocular lens includes creating an intraocular lens mold using a base-polymer, the intraocular lens having a lens center, with a center-transmittance to transmit an incident light; a lens annulus, surrounding the lens center, configured to selectively attenuate the incident light according to a radius and wavelength-dependent annulus-transmittance, wherein the annulus-transmittance is less than the center-transmittance in a short wavelength spectral range; forming haptics, extending from the lens annulus; and applying a stimulus to the intraocular lens mold to form the color-apodized intraocular lens.

Disclosed are high refractive index, hydrophobic, acrylic materials. These materials have both high refractive index and a high Abbe number. This combination means the materials have a low refractive index dispersion and thus are especially suitable for use as intraocular lens materials. The materials are also suitable for use in other implantable ophthalmic devices, such as keratoprostheses, corneal rings, corneal implants, and corneal inlays.