Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.

An orthopaedic implant for filling a bone void and a method of using the same. The orthopaedic implant comprises an open porous metal portion and a bone cement portion. At a first surface region, the open porous metal portion facilitates bone and/or soft tissue ingrowth into the pores of the first surface region of the open porous metal. At a second surface region, the open porous metal facilitates reception of the bone cement into the pores of the second surface region of the open porous metal. The open porous metal portion of the orthopaedic implant may also be formed of a plurality of porous metal fragments aggregated together with the cement portion of the orthopaedic implant. Additionally, the orthopaedic implant may be pliable and thereby capable of being molded to the shape of a void in a bone.

The present disclosure describes a method and device for treatment of bone lesions. The device may include a combination of a drill device, a drill guide, a guide wire, and a syringe. The drill device includes a cannula through which a substance may be injected, an attachment head, and a drill bit. The attachment head may include a fitting for a powered or manual drill and a luer fitting for attaching a syringe or other device. The drill guide includes a cannula with an inner diameter sized to accommodate the cannula of the drill device. The method may include: placing a drill guide near a bone-lesion site, inserting a guide wire through the drill guide, inserting a drill device into the drill guide, removing the guide wire, drilling the bone, and injecting a cellular component and a retention medium into the bone near the lesion site.

Systems for treating and/or preventing fractures include at least one needle sized and configured to be placed into target bone and at least one implantable pin configured to be releasably held in a first needle of the at least one needle. The systems also include at least one delivery device of injectable material configured to couple to the first needle while the first implantable pin is held in the first needle whereby the at least one delivery device and a respective needle cooperate to serially provide an external column of the injectable material about the at least one implantable pin.