The present invention relates to bone-implants for treating a lesion on a bone, comprising: a bone anchor, a container in communication with the bone anchor and an osteoconductive bone-filler material inside the container, and methods thereof.

In some aspects, a device comprising an implant configured for insertion into a portion of human anatomy, and at least one covering coupled to the implant is provided. According to some aspects, the implant comprises one or more protrusions configured to prevent leakage of material and/or to resist displacement of the implant. According to some aspects, the covering is configured to facilitate improved leakage and/or implant displacement prevention.

A methodology for grafting together adjacent bony structures is provided using an implant device having an endplate with an inner disc portion and outer ring portion spaced from the inner disc portion by a connecting wall disposed there between. An endplate interior surface includes a retaining structure for securing the endplate to one of the bony structures, and endplate an exterior surface has an integrally formed socket. A ball-joint rod has a longitudinally extending body and an end, and at least a portion of the ball-joint rod end is curvilinear in shape. The curvilinear ball-joint rod end is rotatably disposed in the endplate socket to fixedly interconnect the bony structures.

A methodology for grafting together adjacent bony structures is provided using an implant device having an endplate with an inner disc portion and outer ring portion spaced from the inner disc portion by a connecting wall disposed there between. An endplate interior surface includes a retaining structure for securing the endplate to one of the bony structures, and endplate an exterior surface has an integrally formed socket. A ball-joint rod has a longitudinally extending body and an end, and at least a portion of the ball-joint rod end is curvilinear in shape. The curvilinear ball-joint rod end is rotatably disposed in the endplate socket to fixedly interconnect the bony structures.

Disclosed are a dental membrane and a dental membrane set including the dental membrane. The dental membrane includes a main plate portion preventing a gum epithelium from first entering a damaged portion and also guiding bone regeneration, by adapting a bone defect portion where a bone defect occurs, and a large area end bending portion forming an end area in one side of the main plate portion, manufactured as one body with the main plate portion, having a larger cross-sectional area than the main plate portion, and being bendable to one side with respect to the main plate portion.

An engineered medical device for treatment of osteonecrosis is provided where the size, porosity and ceramic content of the device can be personalized based on an individual patient's anatomical and physiological condition. The device distinguishes different segments mimicking anatomically-relevant cortical and cancellous segments, in which the cortical segments of the device can sustain mechanical loading, and the cancellous segment of the device can promote bone ingrowth, osteogenesis and angiogenesis.

There is provided a scaffold for bone regeneration which is adapted to be implanted at a bone defect site of a bone. The scaffold comprises a main support member configured to be fixed to the bone, and a load supporting unit configured to be installed in the bone defect site of the bone to selectively bear a load applied to the bone. The load supporting unit includes one or two supporting pieces to be installed in the bone defect site of the bone to selectively bear a load applied to the bone. The supporting piece has at one end portion a contact portion to be brought into contact with and fixed to a compact bone in the bone defect site of the bone. The other end portion of the supporting piece is selectively coupled to the main support member.

An intervertebral implant for supporting vertebrae that includes an anterior end element, a posterior end element, and four wings disposed between the anterior end element and the posterior end element. The four wings and the anterior and posterior end elements define a substantially open central space. The wings are arranged in pairs facing in opposed directions and include teeth facing in those opposed directions for gripping substantially planar surfaces at opposite sides of the implant.

A bone graft containment device includes a plurality of cage segments connected to one another along a longitudinal axis, each of the cage segments connected to an adjacent one of the cage segments via a connection which permits movement of the cage segments relative to one another so that the bone graft containment device is deformable to a desired configuration for placement within a target space of a bone, each cage segment extending along from a first end to a second end and including a channel extending therethrough so that channels of the plurality of cage segments, in an initial configuration, are aligned along the longitudinal axis, the channels configured to be packed with a bone graft material.

A three component system for repairing critically sized bone defects having a first shape memory polymer (SMP) component formed as a scaffold that fills the defects, a second SMP component formed as a restricting sleeve that stabilizes and supports osseointegration and osteoconduction, and a third SMP component formed as a two-dimensional cell culture substrate for engineering periosteal grafts.