A method of growing bone or maintaining orthodontic tooth movement provides a dental device which includes a mouthpiece configured to sit against occlusal surfaces of a patient's teeth and a motor connected to the mouthpiece. The motor is configured to vibrate at a predetermined frequency or acceleration. The method focuses on detecting and measuring the frequency or acceleration at or near the patient's teeth and adjusting the vibration to match the predetermined frequency or acceleration in a feedback loop mechanism mediated by the dental device.

A dental device includes a mouthpiece configured to sit against occlusal surfaces of a patient's teeth and a motor connected to the mouthpiece. The motor is configured to vibrate the mouthpiece at a frequency between 60 and 120 Hz and an acceleration between 0.03 G and 0.06 G such that the mouthpiece places an axial vibratory force on the occlusal surfaces.

An object delivery arrangement is disclosed for delivering objects into bone. The arrangement is configured for generating localized mechanical waves into a tissue, for performing localized deposition of the objects near bone, and for exposing the objects and the bone to said mechanical waves to obtain deposition of the objects into the bone.

A dental device includes a mouthpiece configured to sit against occlusal surfaces of a patient's teeth and a motor connected to the mouthpiece. The motor is configured to vibrate the mouthpiece at a frequency between 60 and 120 Hz and an acceleration between 0.03 G and 0.06 G such that the mouthpiece places an axial vibratory force on the occlusal surfaces.

Embodiments of the present disclosure are directed to devices and methods for stimulating cell proliferation. In one implementation, a method for increasing cell proliferation is provided. The method includes providing a vibrational dental device configured to vibrate at a frequency higher than about 60 Hz. The method also includes mechanically stimulating, using the vibrational dental device, cells for a treatment period of less than about 10 to 20 minutes daily. The method may further include generating a peak acceleration magnitude in the horizontal direction substantially greater than that in the vertical direction. The number of the cells at the end of the period of time is increased. The cells may include at least one of human osteoblasts and fibroblasts.

An implanted piezoelectric bone material includes a main body and a piezoelectric material. The main body is a hollow pillar or a solid pillar. When the main body is the hollow pillar, the hollow pillar has an inner side wall at a center of the hollow pillar and an outer side wall at an outer side of the hollow pillar. When the main body is the solid pillar, the solid pillar only has the outer side wall at an outer side of the solid pillar. The piezoelectric material is in contact with at least one of the inner side wall and the outer side wall.

An interbody implant to be introduced into a variety of target sites for accelerating bone ossification, for example into a space between two adjacent vertebrae. The interbody implant includes a first bone contacting surface, a second bone contacting surface, a body defined between the first and second bone contacting surfaces, and a plurality of resonators. Mechanical waves, e.g., low intensity pulsed ultrasound waves, may be transmitted to the location of the implant, causing the resonators to resonate and accelerate bone ossification.

An interbody implant to be introduced into a variety of target sites for accelerating bone ossification, for example into a space between two adjacent vertebrae. The interbody implant includes a first bone contacting surface, a second bone contacting surface, a body defined between the first and second bone contacting surfaces, and a plurality of resonators. Mechanical waves, e.g., low intensity pulsed ultrasound waves, may be transmitted to the location of the implant, causing the resonators to resonate and accelerate bone ossification.