A method of designing a craniomaxillofacial implant that is a rigid plate of substantially uniform thickness, including: positioning a surface element of the plate as a departure from a reference location within a base outline, the departure being represented by a fraction of the length of a normal path projected from the reference location to a predetermined soft tissue layer at a supported location within an anatomic region of interest, and the fraction being based upon a required patient-specific support at the supported location.

A bone implant including a wire mesh support frame (120A) having a plurality of interconnected wire members and at least two fastening points in the form of retention eyelets (140A) connected to the support frame by deformable retention arms (138A), and a biocompatible plate (112) formed about the support frame, the plate having at least two open cavities (116) therein, wherein each of the retention arms extends out of the plate from or into one of the open cavities. A method for correcting a bone defect in a patient, a mesh support frame for use in a bone implant, and a method of fabricating a bone implant are also provided.

The present disclosure provides a bioresorbable foam closure device for trans-nasally closing an opening in a base of a skull. The closure device comprises a phase-separated polymer. The device includes a stem portion having a proximal end and a distal end, and a head portion at the distal end of the stem portion. The closure device is deformed from a free shape to a constricted shape, inserted through a nasal cavity and into the opening, and released to at least partially revert back to the free shape such that the stem portion fills the opening and the head portion abuts cranium and dura to secure the closure device in position and seal the opening.

A prosthetic implant includes an anterior surface, configured for at least partial contact with an underside of a patient's facial soft tissue. A posterior surface is oppositely placed to the anterior surface. The posterior surface is configured for at least partial contact with a patient's facial bony tissue when the anterior surface is in at least partial contact with the patient's facial soft tissue. An implant body is defined by the anterior and posterior surfaces and extends transversely therebetween. A selected portion of the posterior surface has a texture that mechanically differs from a texture of a majority of the anterior surface.

Various embodiments of craniofacial implants, surgical instruments, and techniques are described to provide improved surgical results.

The present disclosure provides a bioresorbable foam closure device for trans-nasally closing an opening in a base of a skull. The closure device comprises a phase-separated polymer. The device includes a stem portion having a proximal end and a distal end, and a head portion at the distal end of the stem portion. The closure device is deformed from a free shape to a constricted shape, inserted through a nasal cavity and into the opening, and released to at least partially revert back to the free shape such that the stem portion fills the opening and the head portion abuts cranium and dura to secure the closure device in position and seal the opening.

Various embodiments of craniofacial implants, surgical instruments, and techniques are described to provide improved surgical results.

Bioresorbable inflatable devices and tunnel incision tool and methods for treating and enlarging a tissue or an organ or a tube or a vessel or a cavity. The device is composed of a hollow expanding pouch made of a resorbable material that can be attached to a filling element. The pouch can be filled with a biocompatible materials, one or more times in few days interval, after the insertion of the device. While filling the pouch every few days the tissue expands and the filling material if it is bioactive start to function. The tunnel incision tool composed of a little blade that emerges from the surface of the tool in order to make shallow incisions in the surrounding tissue therefore enabling easy expansion of the tissue. This device and method can be used for example for: horizontal and vertical bone augmentation in the jaws and the tunnel incision tool is used to make shallow incisions in the periosteum when using the tunnel technique, sinus augmentation when the device is placed beneath the Schneiderian tissue, vessels widening if the pouch become a stent etc.

In some aspects, the present disclosure provides an implant. In some embodiments, the implant comprises a porous body comprising a form that fills a defect of a bone of a head of a subject. In some embodiments, the implant comprises a recess in the porous body, wherein the recess comprises a dimension larger than an average pore dimension of the porous body. In some embodiments, the implant comprises a biologic disposed in the recess. In some embodiments, the implant comprises an extension.

The present disclosure provides a bioresorbable foam closure device for trans-nasally closing an opening in a base of a skull. The closure device comprises a phase-separated polymer. The device includes a stem portion having a proximal end and a distal end, and a head portion at the distal end of the stem portion. The closure device is deformed from a free shape to a constricted shape, inserted through a nasal cavity and into the opening, and released to at least partially revert back to the free shape such that the stem portion fills the opening and the head portion abuts cranium and dura to secure the closure device in position and seal the opening.