A method for designing an implant includes designing a contour curvature of the implant so that an articulate surface of the implant is designed to correspond to a simulated healthy cartilage surface reconstructed from a 3D model based on one or more images taken with MRI or CT-scanning of a damaged cartilage surface of a joint; and providing a positioning mark on a surface of the implant. The positioning mark is provided such that the positioning mark is parted from the center of the implant to be visible for a surgeon and is adapted to be used for indicating a rotational position of the implant to the surgeon.

A shaped cartilage matrix isolated from a human or animal where the cartilage has been crafted to facilitate disinfection, cleaning, devitalization, recellularization, and/or integration after implantation. Also, a process for repairing a cartilage defect with the cartilage matrix. The matrix is in the form of an osteochondral plug including a cartilage cap ad subchondral bone, wherein one or more gaps, slats, bores, or channels extend through the tidemark at the interface between the cartilage cap and the subchondral bone.

The invention is directed towards a process for implanting a cartilage graft into a cartilage defect and sealing the implanted cartilage graft with recipient tissue by creating a first bore down to the bone portion of the cartilage defect, creating a second shaped bore that is concentric to and on top of the first bore to match the shape and size of the cartilage graft, treating the first bore and the second shaped bore at the defect site with a bonding agent, treating the circumferential area of the cartilage graft with a bonding agent, inserting the cartilage graft into the defect site and wherein the superficial surface of the cartilage graft is at the same height as the surrounding cartilage surface. The first and second bonding agents may be activated by applying a stimulation agent to induce sealing, integration, and restoration of the hydrodynamic environments of the recipient tissue. The invention is also directed towards a process for repairing a cartilage defect and implanting a cartilage graft into a human or animal by crafting a cartilage matrix into individual grafts, cleaning and disinfecting the cartilage graft, applying a pretreatment solution to the cartilage graft, removing cellular debris using an extracting solution to produce a devitalized cartilage graft, implanting the cartilage graft into the cartilage defect with or without an insertion device, and sealing the implanted cartilage graft with recipient tissue. The devitalized cartilage graft is optionally recellularized in vitro, in vivo, or in situ with viable cells to render the tissue vital before or after the implantation. The devitalized cartilage graft is also optionally stored between the removing cellular debris and the recellularizing steps. The invention is further directed toward a repaired cartilage defect.

An implantable medical device for implantation in a hip joint is provided. The medical device comprises: at least one artificial hip joint surface adapted to replace at least the surface of at least one of the caput femur and acetabulum. At least one artificial hip joint surface comprises: a positioning hole with at least one opening in said at least one artificial hip joint surface. The hole is adapted to be placed and dimensioned such that the medical device is adapted to be fitted using a positioning shaft and at least partly surround the shaft, for positioning the at least one artificial hip joint surface in a desired position in the hip joint. The hole is adapted to be fitted using the positioning shaft, when the shaft is stabilized and placed in at least one of the femoral bone and the pelvic bone for positioning said medical device inside the hip joint.

A method for designing an implant includes designing a contour curvature of the implant so that an articulate surface of the implant is designed to correspond to a simulated healthy cartilage surface reconstructed from a 3D model based on one or more images taken with MRI or CT-scanning of a damaged cartilage surface of a joint; and providing a positioning mark on a surface of the implant. The positioning mark is provided such that the positioning mark is parted from the center of the implant to be visible for a surgeon and is adapted to be used for indicating a rotational position of the implant to the surgeon.

Compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles and a biocompatible carrier are provided. Methods of manufacturing cartilage compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles are also provided.

A method for implanting a medical device for lubricating a joint in a human body, said method comprising the steps of creating an opening reaching from outside of the human body into the joint, providing an artificial contacting surface to said joint, fixating the artificial contacting surface to the joint, implanting a reservoir in the human body, and lubricating said artificial contacting surface by pressurizing a lubricating fluid contained in said reservoir.

A system can include a plurality of grouter devices configured to lodge in one or more focal defects located on a pair of articular surfaces; and a plurality of buffer devices configured to fill a space between the pair of articular surfaces; wherein the plurality of grouter devices and the plurality of buffer devices are sized and shaped such that a contact pressure between the pair of articular surfaces is diminished.

A drill tool for implant surgery including a first drill part having a first, smaller diameter for drilling a recess for an implant post and a second drill part having a second, larger diameter for drilling a recess for an implant hat is disclosed. The second drill part has one or more shape cutting edges and one or more sharp pre-cutting edges extending beyond said one or more shape cutting edges.

An implantable medical device for implantation in a mammal joint having at least two contacting surfaces is provided. The medical device comprises; an artificial contacting surface adapted to replace at least the surface of at least one of the mammal's joint contacting surfaces, wherein the artificial contacting surface is adapted to be lubricated, when implanted in said joint. Furthermore the medical device comprises at least one inlet adapted to receive a lubricating fluid from a reservoir, at least one channel at least partly integrated in the artificial contacting surface in connection with the at least one inlet for distributing the lubricating fluid to the surface of the artificial contacting surface. The medical device could be adapted to be operable by an operation device to receive the distributed lubricated fluid from a reservoir.