An implantable medical device is disclosed comprising a thermoplastic composite body having anterior, first lateral, second lateral, posterior, superior, and inferior surfaces, and at least one dense portion and at least one porous portion which are integrally formed. The at least one dense portion is formed of a first thermoplastic polymer matrix that is essentially non-porous, and which is continuous through a thickness dimension from the superior surface to the inferior surface. The at least one porous portion is formed of a porous thermoplastic polymer scaffold having a second thermoplastic polymer matrix which is continuous through the thickness dimension. A method for forming the thermoplastic composite body is disclosed comprising disposing a first powder mixture in a first portion of a mold, disposing a second powder mixture in a second portion of the mold, simultaneously molding the first powder mixture and the second powder mixture, and leaching porogen.

The present invention relates to implantable medical devices (dental and orthopedic) (osseointegrable implants) textured by the additive manufacturing process. Such implants are prepared in such a way as to comprise a larger surface area of contact between implant/adjacent tissues, porous microstructure with complex geometry with controlled and diversified pore size, which confers several technical advantages. In addition, the present invention relates to the process of preparing said implants and/or screws with an optimized structure for accelerating osseointegration. Finally, the present invention refers to the use of said implants as carriers of drugs or cells in order to treat the site, promote its healing, tissue regeneration or promote cell growth.

Hard-tissue implants are provided that include a bulk implant, a face, pillars, slots, and at least one support member. The pillars are for contacting a hard tissue. The slots are to be occupied by the hard tissue. The at least one support member is for contacting the hard tissue. The hard-tissue implant has a Young's modulus of elasticity of at least 3 GPa, and has a ratio of the sum of (i) the volumes of the slots to (ii) the sum of the volumes of the pillars and the volumes of the slots of 0.40:1 to 0.90:1. Methods of making and using hard-tissue implants are also provided.

A system and computer-implemented method for manufacturing an orthopedic implant involves segmenting features in an image of anatomy. Anatomic elements can be isolated. Spatial relationships between the isolated anatomic elements can be manipulated. Negative space between anatomic elements is mapped before and/or after manipulating the spatial relationships. At least a portion of the negative space can be filled with a virtual implant. The virtual implant can be used to design and manufacture a physical implant.

A medical implant includes a first implant body and a pre-coating covering at least a portion of an outer surface of the first implant body. The pre-coating has a negative Poisson's ratio. A method of making a medical implant includes applying a precursor material on a surface of a first implant body, the first implant body having a positive Poisson's ratio. A stimulus is applied to the precursor material, the stimulus causing the precursor material to form a coating having a negative Poisson's ratio

An osteotomy implant includes a first surface extending generally in a first plane and a second surface extending generally in a second plane, oblique to the first plane. The first surface has a perimeter having a first linear edge, a first curve edge connected to the first linear edge, a second linear edge connected to the first curved edge, and a second curved edge connected to the second liner edge.

An artificial articulation having stable fixing means for unicompartmental knee arthroplasty is stably attached to the top of a tibia in order to permit a sliding motion of an artificial joint attached to the bottom of a femur. The artificial articulation includes an implant hat part which a curved surface structure that makes surface contact with the artificial joint attached to the bottom of the femur is formed on an upper surface thereof, and protrusions protruding by a predetermined height in a direction of the top of the tibia are formed in large numbers on a lower surface thereof, and a distally extending stem configured to be formed to protrude downward by a predetermined length from the lower surface of the implant hat part, and to be inserted into the tibia by a predetermined depth from the top of the tibia and attached thereto.

A knee prosthesis comprises a unicondylar knee prosthesis having a unicondylar insert platform and a tibial base attached to a bottom side of the unicondylar insert platform. The unicondylar insert platform has a uniform stiffness gradient (e.g., a density or porosity gradient), whereas the tibial base has a non-uniform stiffness gradient (e.g., a density or porosity gradient) when the tibial base is viewed from a cross-sectional coronal plan. For example, the tibial base may have an area of greatest stiffness or density centrally located relative to an inboard and outboard side of the tibial base. Alternatively, the area of greatest stiffness or density may be located toward the outboard side. Additionally, the tibial base may include density wells having increased density relative to the surrounding area of the tibial base.

Provided is a structure of a porous spinal implant including a cage body inserted between adjacent vertebral bodies and divided by an upper surface, a lower surface, a left surface, a right surface, a front surface, and a rear surface, a plurality of vertical pores formed on the upper surface and the lower surface of the cage body, and a plurality of horizontal structures stacked on the left surface and the right surface of the cage body, wherein the plurality of vertical pores and the plurality of horizontal structures are each formed in a pattern that repeats in up-down, left-right, and front-rear directions. The structure of a porous spinal implant is capable of reducing strength of a cage body close to that of a vertebral body.

The present invention discloses a metal-ceramic composite joint prosthesis and applications and a manufacturing method thereof. The joint prosthesis comprises a metal body and a ceramic body, wherein the metal body is integrally formed and comprises a porous structure layer, a boundary layer and a root-like layer, the boundary layer is located between the porous structure layer and the root-like layer, the root-like layer comprises a plurality of root-like filament clusters connected to the boundary layer but not in contact with one another, each root-like filament cluster comprises a main root perpendicularly connected to the boundary layer and a plurality of fibrous roots connected to the lateral side of the main root, the fibrous roots extend obliquely towards the side away from the boundary layer, and the ceramic body covers the root-like filament clusters and is formed on the boundary layer. The joint prosthesis achieves the compositing of metal and ceramic, thereby achieving both a wear-resistant ceramic body required for a joint friction surface and a porous metal structure with a good bone ingrowth effect required for an osseointegration surface. The root-like filament clusters of the root-like layer are rooted in the ceramic body, to form a tight and stable connection between the ceramic body and the metal body, and the root-like clusters being not in contact with one another prevents the ceramic body from locally breaking or cracking.