An oblique expanding fusion cage device including a body with a superior portion and an inferior portion. The superior portion and the inferior portion have a proximal end and a distal end. The fusion cage device also includes a pathway, an opening, and an expanding member. The pathway travels from the proximal end to the distal end of the device between the superior and inferior portions. The opening in the proximal end of the body enables access to the pathway. The expanding member may be removably inserted into the opening and is moveable toward the distal end of the body, wherein the expanding member engages the superior portion and the inferior portion as the expanding member moves distally within the pathway.

Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.

A medical implant has a textured tissue contact surface comprising a roughened surface that includes a plurality of macroscale and microscale projections and recesses and a plurality of nanostructures on the projections and within the recesses. The nanostructures comprise a plurality of spaced elongated waves, each wave having a crest and a trough. Each wave and recess comprise a plurality of individual polygonal structures, some of which comprise pyramidical-type shapes. The textured tissue contact surface is formed by initially laser ablating a tissue contact surface on the implant with a nanosecond pulsed laser followed by laser ablating the initially ablated surface with a femto-second pulsed laser.

Bioresorbable inflatable devices and tunnel incision tool and methods for treating and enlarging a tissue or an organ or a tube or a vessel or a cavity. The device is composed of a hollow expanding pouch made of a resorbable material that can be attached to a filling element. The pouch can be filled with a biocompatible materials, one or more times in few days interval, after the insertion of the device. While filling the pouch every few days the tissue expands and the filling material if it is bioactive start to function. The tunnel incision tool composed of a little blade that emerges from the surface of the tool in order to make shallow incisions in the surrounding tissue therefore enabling easy expansion of the tissue. This device and method can be used for example for: horizontal and vertical bone augmentation in the jaws and the tunnel incision tool is used to make shallow incisions in the periosteum when using the tunnel technique, sinus augmentation when the device is placed beneath the Schneiderian tissue, vessels widening if the pouch become a stent etc.

Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.

An orthopaedic implant includes: an implant body having an outer surface; and a textured porous material attached to the outer surface and having a plurality of pores and a plurality of islands extending away from the outer surface, the plurality of islands being configured to shear biological tissue during implantation.

A method of producing an interbody spinal implant. The method includes the steps of obtaining a blank having a top surface, bottom surface, opposing lateral sides, and opposing anterior and posterior portions, and applying a subtractive process (e.g., masked acid etching) to the top surface, the bottom surface, or both surfaces of the blank to form a roughened surface topography. Subsequently, the blank is machined to form the interbody spinal implant, which includes a body having a top surface, a bottom surface, opposing lateral sides, opposing anterior and posterior portions, a substantially hollow center, and a single vertical aperture where the top surface, the bottom surface, or both surfaces of the interbody spinal implant have the roughened surface topography produced by the subtractive process. This simplified method produces more accurate and repeatable implants with fewer process steps and defects, reducing process time and costs.

Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.

The invention relates to a method for modification of a biocompatible component. The method of the invention includes the steps of a) providing a biocompatible component at least partly covered by metallic oxide; and b) treating at least a part of the component, which part is covered by the metallic oxide, with an aqueous composition that includes oxalic acid; whereby a modified metallic oxide, is obtained. The invention also relates to a biocompatible component-including a substrate having a surface with a) a microstructure including pits separated by plateus and/or ridges; and b) a primary nanostructure being superimposed on the microstructure, the primary nanostructure having depressions arranged in a wave-like formation.

A spinal implant having a top surface, a bottom surface, opposing lateral sides, and opposing anterior and posterior portions. At least one of the top surface and bottom surface has a roughened surface topography, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction generated when the implant is placed between two vertebrae and to inhibit migration of the implant. At least one of the top surface and the bottom surface also includes at least one self-deploying anchor having an expulsion tab and a bone-engaging tip that causes the implant to resist expulsion once the expulsion tab is deployed.