Systems and methods are provided for generating microscale structures and/or nanoscale structures, surface profiles, and surface chemistries on medical devices. Embodiments disclosed herein utilize exposure of pulsed laser radiation on to a surface of a material by a pulsed laser. The pulsed laser according to embodiments disclosed herein is configured to emit at least one laser pulse toward the surface and thereby modify the profile of the surface in order to selectively promote or inhibit bioactivity and medical functionality of the material. By selectively promoting or inhibiting bioactivity of the material, enhanced biointegration at a cellular level may be achieved. For example, modifying the surface profile and/or surface chemistry of a first substrate material can improve adhesive and/or chemical bonding of the first material to a bioactive second coating material.

Embodiments described include devices and methods for forming a porous polymer material. Devices disclosed and formed using the methods described a spacer for spinal fusion, craniomaxillofacial (CMF) structures, and other structures for tissue implants.

An intervertebral implant with two opposite contact surfaces configured to bear regionally on vertebral bodies and are spaced apart from each other along a vertical axis and are each arranged on support elements which are adjustable relative to each other. The support elements are guided adjustably relative to each other along a circular arc contour oriented on a longitudinal axis extending perpendicular to the vertical axis in such a way that, by adjustment of the two support elements relative to each other along the circular arc contour, a spacing of the two contact surfaces with respect to the vertical axis and/or an angle setting of the two contact surfaces relative to each other can be predefined and/or modified.

In various embodiments, an implant for interfacing with a bone structure includes a web structure including a space truss. The space truss includes two or more planar truss units having a plurality of struts joined at nodes and the web structure is configured to interface with human bone tissue. In some embodiments, a method is provided that includes accessing an intersomatic space and inserting an implant into the intersomatic space. The implant includes a web structure including a space truss. The space truss includes two or more planar truss units having a plurality of struts joined at nodes and the web structure is configured to interface with human bone tissue.

The variable or adjustable depth medical implants in this application are capable of depth adjustment prior to implantation. The variable depth implants permit a single implant to provide multiple footprint configurations, allowing a surgeon footprint adjustability in the operating room. The implants can comprise a metallic lattice designed for specific physical properties, such as an elastic modulus. In some examples, the main body of the implant is taller than the adjustable portion of the implant (also referred to as the second implant body) so that the physical properties of the main body of the implant are controlling at the implant site. In some embodiments, the variable implant is constructed in an additive process as a single unit.

Systems and methods discussed herein provide for fabricating orthopedic implants one or more shape-memory alloys including TiNi and TiNb and shape-setting the alloys to the geometry appropriate for the orthopedic implant. The shape-setting may include tuning the transformation temperature of the one or more alloys, and a single implant may comprise one or more alloys that may differ in composition, shape-setting process, or both.

An intervertebral implant for implantation in an intervertebral space between vertebrae. The implant includes a body extending from an upper surface to a lower surface. The body has a front end, a rear end and a pair of spaced apart first and second side walls extending between the front and rear walls such that an interior chamber is defined within the front and rear ends and the first and second walls. The body defines an outer perimeter and an inner perimeter extending about the internal chamber. At least one of the side walls is defined by a solid support structure and an integral porous structure, the porous structure extending from the outer perimeter to the inner perimeter. The porous structure embeds or encapsulates at least a portion of the solid support structure.

Orthopedic implants produced by additive manufacture, followed by refinement of exterior and interior surfaces trough mechanical erosion, chemical erosion, or a combination of mechanical and chemical erosion. Surface refinement removes debris, and also produces bone-growth enhancing micro-scale and nano-scale structures.

The invention concerns an expandable intersomatic cage (1) intended to be implanted between a first and second vertebral bodies of a patient, comprising: a cage body (2), comprising a bearing surface (6A) intended to be positioned so as to bear against the first vertebral body (4), an expansion cap (3) mounted on the cage body (2) so as to be able to pivot relative to the bearing surface (6A), said expansion cap (3) comprising an element (3A) for bearing against the second vertebral body (5), a means (16) for controlling the inclination of the expansion cap (3). said cage (1) being characterized in that the body (2) comprises at least one fastening orifice (41) forming an oblique well (42) capable of receiving and guiding from the outside of said cage (1) a means for fastening the cage (1) to the first and/or to the second vertebral body. Surgical implants.

An expandable intervertebral spacer includes a body, a proximal end, and a distal end. The body includes quadrants that form a substantially cylindrical shape in a first configuration and a substantially cuboidal shape in a second configuration. Each quadrant includes a ramp portion with a ramp and a landing and a sliding portion with a sliding side and a foot. The ramp portion of a first quadrant engages the sliding portion of a second quadrant. The proximal end and the distal end couple with the plurality of quadrants and transfer an actuating force to expand the body from the first configuration to the second configuration.