A method and a computer system is provided for designing a mandibular joint prosthesis for a patient's skull side to be treated. The method matches a standardized model of the mandibular joint to a graphic representation of the patient's healthy skull side and mirrors the model along a mirror plane onto a graphic representation of the skull side to be treated in order to make corresponding detailed adaptations.

The disclosed embodiments relate to a temporomandibular joint prosthesis including a joint portion, a fixation portion, and at least one flexible unit. The joint portion is configured to be as a temporomandibular joint and movably connected to cranial skeleton. The fixation portion is configured to be fixed on mandible. The flexible unit is located between and connected to the joint portion and the fixation portion. The fixation portion is movable with respect to the joint portion via the flexible unit.

Methods and compositions for the biological repair of cartilage using a hybrid construct combining both an inert structure and living core are described. The inert structure is intended to act not only as a delivery system to feed and grow a living core component, but also as an inducer of cell differentiation. The inert structure comprises concentric internal and external and inflatable/expandable balloon-like bio-polymers. The living core comprises the cell-matrix construct comprised of HDFs, for example, seeded in a scaffold. The method comprises surgically removing a damaged cartilage from a patient and inserting the hybrid construct into the cavity generated after the foregoing surgical intervention. The balloons of the inert structure are successively inflated within the target area, such as a joint, for example. Also disclosed herein are methods for growing and differentiating human fibroblasts into chondrocyte-like cells via mechanical strain.

The invention relates to an implantable partial temporomandibular joint prosthesis (90, 90′, 90″) having a first implant part (10, 10′, 10″) that can be fastened to a lower jaw (40) and has a condyle (42, 42′, 42″) with respect to which a joint surface (52, 82) situated on a cranium (50) forms an abutment; wherein the first implant part (10, 10′, 10″) comprises a first component (20, 20′, 20″) formed from a metal material, which first component can be fastened to the lower jaw (40), and a second component (30, 30′, 30″) formed from a plastics material, which second component comprises the condyle (42, 42′, 42″); and wherein the first component (20, 20′, 20″) is provided with a first connection piece (22, 22′, 22″) and the second component (30, 30′, 30″) is provided with a second connection piece (32, 32′, 32″), and the first connection piece (22, 22′, 22″) and the second connection piece (32, 32′, 32″) can be or are

The present disclosure pertains to ionic polymer compositions, including semi.- and fully interpenetrating polymer networks, methods of making, such ionic polymer compositions, articles made from such ionic polymer compositions, and methods of making such articles and packaging, for such articles.

The invention relates to biodegradable, biocompatible materials to promote regeneration of articular surfaces in the temporomandibular joint and, more particularly, to biomaterials and methods for facilitating fibrochondrocyte and chondrocyte growth in in-vitro and in-vivo environments. The materials include magnesium in solid form and polymer. The materials are effective to grow and regenerate fibrochondrocyte and chondrocyte cells, and restore bone cells.

A biomedical implant (16, 18) is formed from magnesium (Mg) single crystal (10). The biomedical implant (16, 18) may be biodegradable. The biomedical implant (16, 18) may be post treated to control the mechanical properties and/or corrosion rate thereof said Mg single crystal (10) without changing the chemical composition thereof. A method of making a Mg single crystal (10) for biomedical applications includes filling a single crucible (12) with more than one chamber with polycrystalline Mg, melting at least a portion of said polycrystalline Mg, and forming more than one Mg single crystal (10) using directional solidification.

A muscle function preservation type total temporomandibular joint prosthesis includes an articular fossa member (1) and an articular head member (2) abutting against the articular fossa member (1). The articular head member (2) includes a mandibular trailing edge fixing plate (21), a sigmoid notch fixing plate (22) and an articular head portion (23). The mandibular trailing edge fixing plate (21) is connected to a bottom end of the articular head portion (23) and extends downwards, and has a plate-shaped structure and includes a mandibular-trailing-edge-surface attaching surface. The sigmoid notch fixing plate (22) protrudes from one side of the mandibular trailing edge fixing plate (21) and extends in a direction away from the mandibular trailing edge fixing plate (21), and has a plate-shaped structure and includes a mandibular-ramus-proximal-sigmoid-notch-portion attaching surface.

The present disclosure pertains to ionic polymer compositions, including semi- and fully interpenetrating polymer networks, methods of making such ionic polymer compositions, articles made from such ionic polymer compositions, and methods of making such articles and packaging for such articles.

The present disclosure pertains to ionic polymer compositions, including semi- and fully interpenetrating polymer networks, methods of making such ionic polymer compositions, articles made from such ionic polymer compositions, and methods of making such articles and packaging for such articles.