The present invention discloses a connected structure of a porous surface structure and a substrate, a method for preparing the same, and a prosthesis of the same. The connected structure consists of a pre-connected or integrally formed composite body of a porous surface structure and an intermediate; and a substrate, which is connected to said intermediate to achieve the connection of said composite body to the said substrate; the composite body comprising a first composite region corresponding to a first stiffness; a remaining composite region in the composite body other than the first composite region, which at least contains a second composite region corresponding to a second stiffness; and the first stiffness is less than the second stiffness. The present invention achieves a fastened connection between the composite and the substrate and largely maintains the mechanical properties of the substrate; and it provides a prosthesis with excellent bone ingrowth properties and that the strength of the substrate is not substantially affected.

A method of implanting a medical device including forming a tunnel at least partially through a patient's bone, placing the medical device on the bone so that a stress-diffusion element (i.e., a stem) extending from the medical device at least partially extends into the tunnel, and securing the medical device to the bone. The medical device includes a hemispherical cup having a bone-abutment exterior surface, an interior surface defining a cavity, a circumferential rim extending between the exterior surface and the interior surface, and at least one aperture extending between the exterior surface and the interior surface. The stress-diffusion element is formed to extend from and be oriented with respect to the cup based on whether the surgical implant is to be used on a left side or right side of the patient for reconstruction of the segmental acetabular defect.

A method of implanting a medical device including forming a tunnel at least partially through a patient's bone, placing the medical device on the bone so that a stress-diffusion element (i.e., a stem) extending from the medical device at least partially extends into the tunnel, and securing the medical device to the bone. The medical device includes a hemispherical cup having a bone-abutment exterior surface, an interior surface defining a cavity, a circumferential rim extending between the exterior surface and the interior surface, and at least one aperture extending between the exterior surface and the interior surface. The stress-diffusion element is formed to extend from and be oriented with respect to the cup based on whether the surgical implant is to be used on a left side or right side of the patient for reconstruction of the segmental acetabular defect.

A medical device for treating hip joint osteoarthritis in a human patient by providing at least one artificial hip joint surface. The medical device comprises a prosthetic part or a bone plug adapted to be placed in a hole in the pelvic bone and a supporting member connected to said prosthetic part or bone plug, wherein the prosthetic part or the bone plug is adapted to be inserted into said hole from the abdominal side of the acetabulum and oriented, during the insertion, such that the concave interior surface is facing in the direction towards the caput femur. Wherein the medical device comprises an artificial caput femur surface or artificial acetabulum surface, and wherein a largest cross-sectional distance of said artificial caput femur or acetabulum surface is smaller than said hole, such that said artificial caput femur surface can pass through said hole.

Systems and methods are described to determine joint center of rotation during a procedure. Joint center measurements may be useful to determine other clinically relevant measurements and/or to assist with replacement surgery.

Systems and methods are described to determine joint center of rotation during a procedure. Joint center measurements may be useful to determine other clinically relevant measurements and/or to assist with replacement surgery.

Implantable drug-eluting device (1) comprising a microporous structure (2) having regularly arranged pores (4, 5) in at least two different uniform sizes, and manufacturing method. The pores are configured for receiving a drug (9) and are being connected by interconnections (6, 7). Interconnections (6) originating from pores (4) of a first size have a first elution area and interconnections (7) originating from pores (5) of a second size have a second elution area. The interconnections convey the drug (9) to a surface of the device for elution to surrounding tissue. The ratio between the first and the second elution areas is predefined and selectable. The differently sized elution areas provide for different outflow rates. This allows for simple but reliable dispensing of drugs at positively controlled and well determined rates. Particularly, this enables a single implantable device to dispense drugs over preselectable durations of time, like short-term or long-term.

Implantable drug-eluting device (1) comprising a microporous structure (2) having regularly arranged pores (4, 5) in at least two different uniform sizes, and manufacturing method. The pores are configured for receiving a drug (9) and are being connected by interconnections (6, 7). Interconnections (6) originating from pores (4) of a first size have a first elution area and interconnections (7) originating from pores (5) of a second size have a second elution area. The interconnections convey the drug (9) to a surface of the device for elution to surrounding tissue. The ratio between the first and the second elution areas is predefined and selectable. The differently sized elution areas provide for different outflow rates. This allows for simple but reliable dispensing of drugs at positively controlled and well determined rates. Particularly, this enables a single implantable device to dispense drugs over preselectable durations of time, like short-term or long-term.

A medical implant includes a first implant body and a pre-coating covering at least a portion of an outer surface of the first implant body. The pre-coating has a negative Poisson's ratio. A method of making a medical implant includes applying a precursor material on a surface of a first implant body, the first implant body having a positive Poisson's ratio. A stimulus is applied to the precursor material, the stimulus causing the precursor material to form a coating having a negative Poisson's ratio

A medical implant includes a first implant body and a pre-coating covering at least a portion of an outer surface of the first implant body. The pre-coating has a negative Poisson's ratio. A method of making a medical implant includes applying a precursor material on a surface of a first implant body, the first implant body having a positive Poisson's ratio. A stimulus is applied to the precursor material, the stimulus causing the precursor material to form a coating having a negative Poisson's ratio