The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In an exemplary embodiment, the present invention provides an intervertebral implant. The intervertebral implant may be configured to transition from a collapsed configuration having a first height and a first width to an expanded configuration having a second height and a second width.

An intervertebral insert member and an instrument for positioning the insert in a space between vertebral bodies in vivo. The insert member is advanced by the instrument into a prepared site located between adjacent vertebral bodies. Upon reaching the appropriate insertion point, the sleeve is retracted and a pivotal motion is imparted to the insert. The insert member is pivotally attached to the distal end of the delivery instrument such that it can be articulated about a pivot point that is located on the insert member until it is properly positioned. The positioning instrument is then released from the insert member and removed from the space between the vertebral bodies. An adjustment screw is available to expand the surfaces of the insert member by displacement of a wedge member within the insert.

Patient-specific systems and methods are provided for assisting in medical procedures, and can include producing patient-specific devices from computer models of a patient's anatomy, including a first patient-specific device configured to identify and allow access to a resection area in an operation location for a medical procedure; a second patient-specific device configured to refine the procedure, following use of the first patient-specific device and in some embodiments, to identify and allow access to installation locations for an implant and/or surgical hardware; and/or a third patient specific device configured to assist in confirming placement of the implant and/or surgical hardware and refining the procedure, following use of the first and second patient-specific devices. Each of these devices may be developed from patient-specific computer model data via patient-specific image data and may enhance a variety of procedures.

An implant including first and second end plates, each of which defines at least one anterior ramped surface and at least one posterior ramped surface. A posterior actuator is positioned between the first and second end plates and has guiding ramp surfaces which correspond with the posterior ramped surfaces. An anterior actuator is positioned between the first and second end plates and guiding ramp surfaces which correspond with the anterior ramped surfaces. An actuator assembly extends between the posterior actuator and the anterior actuator and is configured to selectively move the posterior actuator and the anterior actuator simultaneously, move posterior actuator independently of the anterior actuator, or move the anterior actuator independently of the posterior actuator.

Disclosed is a bone fusion cage that contains bone graft and is implanted between bones in a skeletal system. The cage bears structural loads that are transmitted through the bones of the skeletal system and at least partially shields the contained bone graft from the structural loads. The cage is configured to provide a secondary load to the bone graft independent of the structural load to promote fusion of the bone graft to adjacent bones.

An expansible, multi-chambered implant for use in a tissue prosthesis receiving cavity including an expansible envelope having a plurality of chambers, wherein the expansible envelope includes a first member, a second member and at least one collapsible partition extending in an interior of the expansible envelope between the first member and the second member, and a filler tube operatively connected to the expansible envelope such that the filler tube includes a plurality of delivery tubes, wherein one of the plurality of delivery tubes is operatively connected to one of the plurality of chambers and another of the plurality of delivery tubes is operatively connected to another of the plurality of chambers in order to independently fill each of the plurality of chambers.

An expandable interbody implant is expandable from a contracted configuration to an expanded configuration by moving opposing first and second vertebral-engaging surfaces apart from one another. The implant includes a locking system for restraining contraction of the implant. The locking system may have a locked configuration, in which the first and second surfaces are prevented from moving back towards the contracted configuration, and the locking system may have an unlocked configuration, in which the first and second surfaces are permitted to move back towards the contracted configuration. The locking system may be controlled by rotation of one or more pinions. The pinions may, in turn, be controlled by linear movement of a rack. The rack may be configured so as to bias the locking system towards the locked configuration. The implant may also include a stop for constraining the maximum expansion of the implant.

Intervertebral endoprosthesis discs suitable for surgical implantation between two vertebrae having and methods thereof. The prosthetic disc may have an endoprosthesis body including an anterior region and a posterior region designed to be positioned between a first vertebra and a second vertebra with a first and second movable insert positioned rotatably in anterior cavities and is rotatable to adjust the fasteners.

A flexible chain implant for insertion into an interior volume of a vertebral body. The implant may be implanted in an insertion position for sliding through a cannula and is flexible for packing into the interior volume in an implanted configuration. The implant randomly separates in the implanted configuration. The implant includes a top member and a bottom member, wherein the top and bottom members are coupled to one another at a coupled portion. The top and bottom members preferably each include an inner surface such that the inner surfaces include a plurality of alternating projections and recesses so that the projections are received within the recesses in an insertion position. Alternatively, the implant may include a plurality of substantially non-flexible bodies and a plurality of substantially flexible links interconnecting the bodies. The non-flexible bodies include a plurality of facets and/or abutment surfaces.

Arcuate fixation members with varying configurations and/or features are provided, along with additional components for use therewith in provided fixation systems and intervertebral implant systems. The arcuate fixation members may be of varying lengths, cross sectional geometries, and/or cross sectional areas, and may be configured with various features such as heads configured to accept other fixation system components, tabs to allow arcuate fixation member-in-arcuate fixation member or fixation anchor-in-arcuate fixation member configurations. Applications of fixation systems and intervertebral implants systems utilizing arcuate fixation members are particularly suitable when a linear line-of-approach for delivering fixation members is undesirable.