An intervertebral spacer may include a fastener channel configured to receive a fastener, a locking member channel, and a locking member. The locking member channel may include an inner wall and one or more inner wall engagement features. The locking member may include an anti-backout member, a collet retainable within the locking member channel, and one or more collet engagement features. The locking member may be rotatable within the locking member channel between an unlocked position and a locked position. The one or more collet engagement features may engage the one or more inner wall engagement features in order to retain the locking member in either the unlocked position or the locked position, such that the anti-backout member may selectively obstruct the fastener channel and prevent the fastener from backing out of the fastener channel.

The present invention is an implant for bone. The current implant is particularly useful in spinal surgical procedures.

A spinal implant includes a body having opposite first and second end walls and opposite first and second side walls. The side walls each extend from the first end wall to the second end wall. A first cap is coupled to top ends of the walls. A second cap is coupled to bottom ends of the walls. The implant includes an opening extending through the caps such that the first cap defines a first ledge extending from the walls to the opening and the second cap defines a second ledge extending from the walls to the opening. Systems and methods of use are disclosed.

Disclosed are engineered vertebral disc implants comprising an engineered vertebral disc, wherein the engineered vertebral disc comprises a nucleus pulposus region and an annulus fibrosus region; and two endplates, wherein the endplates comprise a porous polymer foam, and wherein the endplates comprise channels. Disclosed are methods of treating disc degeneration comprising implanting one or more of the disclosed engineered vertebral disc implants to a subject in need thereof, wherein the endplates of the engineered vertebral disc implant are attached to the vertebra of the subject.

A method for inserting an intervertebral disc prosthesis into a space between two vertebrae involves inserting the prosthesis partway into the space under constraint to prevent endplates of the prosthesis from articulating, releasing the prosthesis from constraint, and inserting the unconstrained prosthesis farther into the space. In some embodiments, the method involves grasping the prosthesis with a grasping device to insert the prosthesis partway under constraint, loosing the grasping device to release the prosthesis from constraint, and pushing the prosthesis farther into the disc space using the grasping device and/or one or more separate pusher devices. A system includes a grasping device, at least one separate pushing device, and optionally a vertebral spreading device and/or a vertebral midline indicator device.

An artificial replacement disc includes a pair of substantially parallel plates formed to occupy a space defined by vertebral endplates, each of the plates including a plurality of spikes on a first surface and a concave trough formed on a second surface opposite of the first surface. A mobile core includes a core rim with opposing convex surfaces extending from opposite sides of the core rim, the mobile core being capable of being disposed between the pair of plates to permit the vertebral endplates to move relative to one another. The spikes on each of the plates extend substantially away from the mobile core and the convex surfaces are formed to integrally fit within the concave trough of at least one of the plates. The core rim limits lateral movement of the mobile core relative to the parallel plates. One or more insertion tools for inserting and implanting the replacement disc are also described.

A fusion cage has a first component that defines an outside surface that is configured to engage a vertebral endplate, and an interior surface. The fusion cage has a second component that defines first and second opposed surfaces. One of the first and second opposed surfaces can mate with the interior surface of the first component. The fusion cage can include vertical and lateral throughholes adapted to enhance fusion.

An expandable implant for treating bone preferably in a minimally invasive manner includes a preferably cylindrical core element extending along a longitudinal axis and preferably a plurality of nestable, expandable sleeves extending along a longitudinal axis for placement radially about the core element. The plurality of nestable sleeves are sequentially insertable over the core element in such a manner that a first nestable sleeve is inserted over the core element and each subsequently inserted nestable sleeve is received between the core element and the previously inserted nestable sleeve such that the insertion of each additional sleeve causes each previously inserted sleeve to outwardly expand.

An expandable implant is disclosed in which the implant includes top and bottom plates having angled inner surfaces that interact with expansion members. The expansion members may be situated on an actuator, and may include at least one vertical projection. In some instances, rotation of the actuator in opposing directions about a longitudinal axis may cause the expansion members to move toward or away from one another, thereby resulting in separation of the top and bottom plates. During such expansion of the implant, the at least one vertical projection of the expansion members may be guided at least partially within a recess formed in the first or second plate. Pins may also be included with the expansion members that ride along respective slots in the plates during expansion. An insertion instrument for implanting the aforementioned implant, and methods of using the same, are also disclosed.

An intervertebral implant for being implanted between adjacent vertebrae is provided. The implant includes a generally elongate implant body having a length extending between opposite longitudinal ends thereof, a superior face and an inferior face. The superior face and inferior face include cortical teeth adjacent to the implant body longitudinal ends. Additionally, the superior and inferior faces include longitudinally central teeth intermediate the cortical teeth and have bone engaging ends. The central teeth have a sharper configuration than that of the cortical teeth bone engaging ends for biting into the softer central bone material of the vertebrae. The cortical teeth are arranged in a first density per unit area and the central teeth are arranged in a second density per unit area that is less than the first density.