An infection treatment system includes a first intramedullary rod for placement within an intramedullary canal and including a superior portion having a superior end, an inferior portion having an inferior end, and a shaft extending longitudinally between the superior and inferior portions. The shaft includes longitudinally extending channels. A second intramedullary rod for placement within an intramedullary canal includes a superior portion having a superior end, an inferior portion having an inferior end, and a shaft extending longitudinally between the superior and inferior portions. The shaft includes longitudinally extending channels. A coupler is operatively attached to the rods. The coupler has a superior face, an inferior face, an anterior face, a posterior face, a first lateral face and a second lateral face. At least one of the faces includes at least one opening in fluid communication with at least a portion of the channels of the first and second rods.

An implant for repairing an articular cartilage defect site including an implant fixation portion with an upper segment and at least one bone interfacing segment and a top articulating portion with an articulating surface and an engagement surface. The upper segment includes a supporting plate with a first locking mechanism segment. The engagement surface includes a second locking mechanism segment. The first locking mechanism segment with at least two channels is structured to couple to the second locking mechanism segment with at least two protrusions. The at least one bone interfacing segment structured for insertion into the articular cartilage defect site. An implant including an implant fixation portion, a top articulating portion, and a locking mechanism with a first locking segment coupled to the upper segment and a second locking segment coupled to the at least one engagement surface and structured to couple to the first locking segment.

A mixing device for bone cement is provided. The mixing device includes a mixing handle, an housing, and a mixing paddle. The mixing handle having a rod, where at least portions of the rod are in tubular form with monomer inside of the rod. The housing has a mixing chamber in which the monomer and a powder are miscible. The mixing paddle is arranged in the mixing chamber and is movable via the rod.

A tissue prosthesis insertion system (80) includes a first assembly (10) comprising a plurality of nested tubes (12), one of the tubes being a carrier tube (14) which, in use, receives a component (16) of a tissue prosthesis at a distal end of the carrier tube (14). A magnetic mount (44) is carried at a proximal end of the first assembly (10). A second assembly (82) is removably attachable to the first assembly (10). An attachment device (92) is carried at a distal end of the second assembly (92), the attachment device (92) being responsive to the magnetic mount (44) of the first assembly (10), the magnetic mount (44) and the attachment device (92) carrying complementary engaging formations to facilitate hermetic sealing between the magnetic mount (44) and the attachment device (92).

A system for repairing a defect on an articular surface of a patient's trochlear region, the system comprising a guide block comprising a body having an exterior surface configured to engage with the saddle portion and ridge portions of the patient's trochlear region, a protrusion extending generally from the body and configured to be received in a first bore formed in the articular surface along a reference axis, and a first cavity extending through the body configured to establish a first working axis displaced from the reference axis, wherein the exterior surface of the body and the protrusion are configured to secure the location of the guide block about the patient's trochlear region. A method for preparing an implant site in bone, comprising: establishing a reference axis extending from the bone; creating a bore in the bone by reaming about the reference axis; securing a guide block about the articular surface; establishing a first working axis extending from the bone using the guide block, the first working axis is displaced from the reference axis; and creating a first socket in the bone by reaming about the first working axis, wherein the first socket partially overlaps with the bore.

A medical system and method can used to treat a bone. The system and method can include the preparation of bone cement to be used in the treatment. A non-liquid component and a liquid component can be combined to form a bone cement. A vacuum system can be used to saturate the non-liquid component with the liquid component. The bone cement and/or components can be heated and/or cooled.

A method and apparatus for preventing brain compression subsequent to removal of a portion of a patient's cranium comprises custom forming a protective external cranial plate. The protective external cranial plate is shaped to approximate the removed portion of the patient's cranium, and to extend peripherally beyond the removed portion. The protective external cranial plate is affixed in airtight and fluid tight engagement to the scalp of the patient.

A tissue insertion prosthesis system includes an expansible, multi-chambered implant for use in a tissue prosthesis receiving cavity, such that the implant includes an expansible envelope having a plurality of chambers. The system also includes a method of determining a size of a cavity at a site to be filled by a tissue prosthesis. Finally, the system includes a method to facilitate a removal of a biomaterial delivery device from an inflatable member that has been inserted into a cavity formed by the removal of a portion of a nuclear material from an intervertebral disc and to be filled by a tissue prosthesis.

Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.

A method of locating an acetabular cup implant (100) in a pelvis comprises locating a plurality of reference points on the pelvis, defining a target location of the implant relative to the reference points, and placing the implant at the target location. A method of locating a femoral head implant (102) is also disclosed, together with associated guidance systems.