A delivery device for a prosthetic heart valve includes a catheter assembly and an operating handle. The catheter assembly may include an inner shaft around which a compartment for the heart valve is defined, and a distal sheath having proximal and distal segments configured to enclose the compartment. The handle may include a first lead screw coupled to the proximal segment and a second lead screw coupled to the distal segment. Actuation of the first lead screw operates to move the proximal segment of the distal sheath proximally and actuation of the second lead screw operates to move the distal segment of the distal sheath distally to uncover the compartment and deploy the heart valve.

Described herein are flexible implantable occluding devices that can, for example, navigate the tortuous vessels of the neurovasculature. The occluding devices can also conform to the shape of the tortuous vessels of the vasculature. In some embodiments, the occluding devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. Some embodiments describe methods and apparatus for adjusting, along a length of the device, the porosity of the occluding device. In some embodiments, the occluding devices allows adequate blood flow to be provided to adjacent structures such that those structures, whether they are branch vessels or oxygen-demanding tissues, are not deprived of the necessary blood flow.

Defining proximal as toward the heart and distal as away from the heart, a sheath includes a proximal opening and multiple fenestrations maintainable in position slightly beyond a site or point of sheath entry into a vessel by way of an anchoring assembly having a set of radially displaceable anchoring elements configured for abutting a superficial vessel wall. The fenestrations and/or anchoring element(s) are arranged obliquely or non-obliquely around peripheral portions of the sheath. The sheath can receive blood from a pumping source at a proximal opening, and channel the blood toward, to, and through the fenestrations. The fenestrations, in combination with the proximal opening, enable the perfusion of blood into the cannulated vessel in a set of distal directions for perfusing a distal tissue or organ. Flow of blood out of fenestrations directs blood distally towards the limb, head, or other distal region, mitigating the risk of or preventing ischemia.

Defining proximal as toward the heart and distal as away from the heart, a sheath includes a proximal opening and multiple fenestrations maintainable in position slightly beyond a site or point of sheath entry into a vessel by way of an anchoring assembly having a set of radially displaceable anchoring elements configured for abutting a superficial vessel wall. The fenestrations and/or anchoring element(s) are arranged obliquely or non-obliquely around peripheral portions of the sheath. The sheath can receive blood from a pumping source at a proximal opening, and channel the blood toward, to, and through the fenestrations. The fenestrations, in combination with the proximal opening, enable the perfusion of blood into the cannulated vessel in a set of distal directions for perfusing a distal tissue or organ. Flow of blood out of fenestrations directs blood distally towards the limb, head, or other distal region, mitigating the risk of or preventing ischemia.

An endoprosthesis delivery system includes an expandable endoprosthesis including a side branch portal, a first primary sleeve releasably constraining a proximal portion of the expandable endoprosthesis to a collapsed configuration, a second primary sleeve in parallel with the first primary sleeve, the second primary sleeve releasably constraining a distal portion of the expandable endoprosthesis to the collapsed configuration, and a secondary sleeve within the first primary sleeve. Upon release of the first primary sleeve, the secondary sleeve releasably constrains the proximal portion of the expandable endoprosthesis to a partially expanded configuration allowing access to the side branch portal via the partially expanded proximal portion of the expandable endoprosthesis.

A delivery system (200) for delivering a lumen stent (100). The delivery system (200) comprises a fixing anchor (270) and a fixing cap (260) which is cylindrical and has an opening at a proximal end, the fixing anchor (270) comprising a hollow insertion part (271) and an abutment part (273) connected to the insertion part (271); parts of the side surface of the insertion part (271) are recessed towards the interior of the insertion part (271) to form a plurality of positioning grooves (2711) that extend to a proximal end surface of the insertion part (271), a separator (2713) being formed between every adjacent two positioning grooves (2711); the abutment part (273) comprises a carrier (2731) and a plurality of first position-limiting pieces (2733) provided on a side of the carrier (2731), a distal end of each first position-limiting piece (2733) being provided to correspond to an open side of a positioning groove (2711) adjacent to the abutment part (273); distal end surfaces of the plurality of first position-limiting pieces (2733), a distal end surface of the carrier (2731) and proximal end surfaces of the separators (2713) are coplanar. When the fixing anchor (270) and the fixing cap (260) are joined, the insertion part (271) is inserted into the fixing cap (260), and the distal end surfaces of the first position-limiting pieces (2733) abut the proximal end surface of the fixing cap (260). Further disclosed is a lumen stent system. The delivery system (200) can be smoothly and safely withdrawn out of the human body.

A delivery system for delivering an endovascular prosthesis is disclosed. A handle assembly is disposed at the distal end of the delivery system. The handle assembly includes a main handle and a second handle disposed at least partially on the main handle and rotationally moveable relative to the main handle. A trigger wire release mechanism is operatively coupled to the second handle. A sheath is operatively coupled to the second handle, such that rotation of the second handle relative to the main handle retracts the sheath in a distal direction. Rotation of the handle also moves the trigger wire release mechanism from a first position to a second position to retract one or more trigger wires.

Various aspects of the present disclosure are directed toward apparatuses, systems (200), and methods for deploying a medical device (202). In certain instances, the medical device (202) may be a shunt device. In addition, the apparatuses, systems (200), and methods may include one or more constraining lines (212) arranged through a portion of the implantable medical device (202) and one or more release lines (216) configured to engage the one or more constraining lines (212).

Stent delivery device includes an inner member having a distal tip, a stent disposed over a stent receiving region of the inner member, an outer sheath slidable over the inner member, a stent sheath removably coupled to both the distal tip and a distal end of the outer sheath, and a stent expanding element attached to the distal tip and/or the distal end of the outer sheath. The stent expanding element is biased in an elevated position and aids expansion of the stent when the stent sheath is removed. The stent delivery device includes a proximal junction removably coupling the distal end of the outer sheath to the stent sheath, and a proximal junction removably coupling the stent sheath to the distal tip. Each of the proximal and distal junctions are separately actuatable to decouple the stent sheath from either the distal tip or the outer sheath.

The present disclosure describes medical devices comprising implantable expandable implants, such as stent-grafts. Such devices can comprise a constraining line. The constraining line can surround the proximal end of the expandable implant, and assist in positioning and deployment of the expandable implant within the body of the patient.