A stent graft delivery system. The system includes a stent graft cover having a central longitudinal axis. The stent graft cover houses a first guidewire lumen extending along a first guidewire lumen axis and configured to track along a first guidewire. The first guidewire lumen axis is offset the central longitudinal axis. The stent graft delivery system further includes a tapered tip extending distally from the stent graft cover and defining an offset through-channel extending within the tapered tip along a tapered tip offset axis and configured to track along the first guidewire. The first guidewire lumen axis and the tapered tip offset axis extend along a common axis.

A delivery device includes a handle, a central elongate member extending from the handle, a sheath configured to slide over and relative to the central elongate member, a distal tether retainer at a distal end of the central elongate member, a proximal tether restraining mechanism positioned along the central elongate member distal of the handle and proximal of the distal tether retainer, and a plurality of tethers. The tethers are configured to extend from the proximal tether restraining mechanism to the distal tether retainer.

A valve prosthesis and implantation device, and methods for use are provided. The devices may be used for transcatheter delivery of an aortic valve prosthesis or transapical delivery of a mitral valve prosthesis. The implantation device utilizes movable claspers for both positioning and anchoring the valve prosthesis, reducing the extent of imaging needed during the implantation procedure.

A delivery system for delivering an endovascular graft within a blood vessel. The delivery system includes a tip assembly including a tip and a sleeve having an inner surface. The delivery system includes a tip capture mechanism. The tip assembly is configured to move axially relative to the tip capture mechanism and between a delivery position and a release position. The tip capture mechanism includes a cylindrical outer surface and knobs arranged around the cylindrical outer surface. Each knob has a pyramidal structure with a rounded apex. The knobs and inner surface of the sleeve are configured to cooperate to hold a portion of the endovascular graft when the tip capture mechanism and the tip assembly are in the delivery position.

The present disclosure describes medical devices comprising implantable expandable implants, such as stent-grafts. Such devices can comprise a constraining line. The constraining line can surround the proximal end of the expandable implant, and assist in positioning and deployment of the expandable implant within the body of the patient.

A delivery device includes a handle, a central elongate member extending from the handle, a sheath configured to slide over and relative to the central elongate member, a distal tether retainer at a distal end of the central elongate member, a proximal tether restraining mechanism positioned along the central elongate member distal of the handle and proximal of the distal tether retainer, and a plurality of tethers. The tethers are configured to extend from the proximal tether restraining mechanism to the distal tether retainer.

A stent device delivery system and method of making. The stent device delivery system includes a stent device, an outer sheath overlaying the stent device in a radially compact, delivery configuration of the stent device, and a pull member. The outer sheath may include a first layer and a reinforcement layer that are laminated together, a portion of the pull member captured radially between the first layer and the reinforcement layer. At least a partial length of the captured portion of the pull member may be formed with a varying radial profile.

The present embodiments provide systems and methods for facilitating deployment of a stent. In one embodiment, the system comprises an inner cannula, and at least one trigger wire extends at least partially within a lumen of the inner cannula and has an exposed portion extending radially outside of the lumen of the inner cannula. The exposed portion of the at least one trigger wire engages an associated portion of a stent in a delivery state. An outer cannula is sized for longitudinal movement over a portion of the inner cannula. Selective distal retraction of the outer cannula permits partial deployment of the stent to an extent of slack provided by the at least one trigger wire, and selective proximal advancement of the outer cannula incrementally urges the exposed portion of the at least one trigger wire radially inward to constrain the associated portion of the stent.

Methods and devices for delivering a stent in a proximal to distal fashion are disclosed. The delivery device includes a sheath catheter, an outer catheter and an inner catheter over a guide wire. A crimped stent is positioned over the distal end of the outer catheter and is held in place by a lubricous elastic membrane attached to a retractable ring. The retractable ring is connected to pull wires and slidably deployed between the inner and outer catheters. The proximal end of the stent is aligned at the treatment location, and the lubricous elastic membrane is pulled back into the space between inner catheter and outer catheter, releasing and deploying the stent from its proximal to its distal end.

Methods and devices for delivering a stent in a proximal to distal fashion are disclosed. The delivery device includes a sheath catheter, an outer catheter and an inner catheter over a guide wire. A crimped stent is positioned over the distal end of the outer catheter and is held in place by a lubricous elastic membrane attached to a retractable ring. The retractable ring is connected to pull wires and slidably deployed between the inner and outer catheters. The proximal end of the stent is aligned at the treatment location, and the lubricous elastic membrane is pulled back into the space between inner catheter and outer catheter, releasing and deploying the stent from its proximal to its distal end.