Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering the stent through an access site and deploying a distal portion of the stent from within an outer sheath. In some cases, the method may further include pushing a proximal portion of the stent from the outer sheath such that upon fully exiting the outer sheath, the proximal portion extends proximally to at least partially cover the access site with the stent. The system for delivering the stent into the body lumen may include a stent, a stent delivery apparatus, and an outer sheath. The system may further include an internal pusher configured to push a proximal portion of the stent from the outer sheath and axially compress the stent such that upon fully exiting the outer sheath, the proximal portion extends proximally to cover the access site.

Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering a stent delivery system through an access site, where the stent delivery system comprises a positioning member with a first portion that is rotatable with respect to a second portion, and where the stent is releasably coupled with the first portion of the positioning member. In some cases, the method may further include withdrawing an outer constrainment member from the stent to deploy a proximal portion of the stent within the body lumen and rotating the proximal portion of the stent away from the access site by withdrawing the positioning member proximally and back through the access site. The method may further include covering the access site with the proximal portion of the stent upon fully deploying the proximal portion from the outer constrainment member.

A valve prosthesis, an implantation device, and methods for use are provided. The devices described herein may be used for transcatheter delivery of an aortic valve prosthesis or transapical delivery of a mitral valve prosthesis. The implantation device can utilize movable claspers for both positioning and anchoring the valve prosthesis, reducing the extent of imaging needed during the implantation procedure.

A delivery catheter includes a tip, a spindle and a lock mechanism. The tip includes a tapered portion and a tip sleeve. The tip sleeve extends proximally and has a lumen. The spindle includes a plurality of spindle pins. The lock mechanism locks the tip sleeve to the spindle to prevent relative longitudinal movement between the spindle and the tip sleeve. The delivery catheter includes a delivery configuration with the tip sleeve covering the spindle pins and a release configuration with a proximal end of the tip sleeve distal of the spindle pins. The lock mechanism locks the prosthesis delivery system in the release configuration. Each spindle pin of the plurality of spindle pins includes a smooth, curved profile.

A stent delivery system includes a core member and a coupling assembly rotatably coupled to the core member distal segment. The coupling assembly includes first and second plates and first and second spacers. The first plate is rotatably coupled to the core member and includes an outer surface having three or more projections separated by recesses. The first spacer is coupled to the core member and disposed between the first plate and a proximal restraint. The second plate is rotatably coupled to the core member and includes an outer surface having three or more projections separated by recesses. The second spacer is coupled to the core member and disposed between the first plate and the second plate. A stent extends along the core member distal segment such that an inner surface of the stent is engaged by one or more projections of the first plate or the second plate.

Embodiments of the present disclosure provide a delivery device for controlling the release of a stent in a stepwise manner, including: a core assembly, an outer sheath, which is hollow and mounted around an outer periphery of the core assembly, with a delivering gap being defined therebetween which has a distal space for receiving the folded stent; and a stent restraining assembly, configured to restrain a released part of the stent to be partly unfolded when the stent is in a partly released state in such a way to restrain an outer diameter of the released part of the stent, and to make the stent be fully unfolded when the stent is in a completely released state. Embodiments of the present disclosure further provide a delivery system for controlling the release of a stent in a stepwise manner. The present disclosure facilitates adjust the position of the stent.

Embodiments of the present disclosure provide a delivery device configured to deliver a main stent with a fenestration, including a core assembly, an outer sheath, which is hollow and mounted around the core assembly with a delivering gap defined therebetween, and a pre-embedded guidewire. The delivering gap has a distal end for receiving the folded main stent. The pre-embedded guidewire enters the delivering gap through the proximal end thereof and extends to the distal end thereof. The pre-embedded guidewire has a distal end configured to enter into the main stent from an outside thereof via the fenestration, and the pre-embedded guidewire is configured to guide a branch guidewire to pass through the main stent from an inside to the outside thereof via the fenestration. The present disclosure has the advantage of decreasing difficulty for the branch guidewire passing through the main stent.

Stent delivery systems and methods for making and using stent delivery systems are disclosed. An example stent delivery system may include an inner member having a stent receiving region, a stent disposed along the stent receiving region, a deployment sheath axially slidable relative to the inner member, the deployment sheath having a proximal end region, a handle coupled to the deployment sheath, a rod coupled to the handle, the rod having a distal end region, a proximal end region and a first threaded portion extending from the distal end region to the proximal end region and a coupling member configured to couple the rod to the deployment sheath, the coupling member having an engagement portion. Additionally, the first threaded portion of the rod is designed to engage the engagement portion of coupling member and rotation of the rod is designed to translate the coupling member along the rod.

A transcatheter heart valve leaflet replacement system includes a valve prosthesis and a multi-stage, multi-lumen (MSML) heart valve delivery and implantation system for guiding and implanting the prosthesis to a native annulus. The prosthesis includes a stent frame including an upper atrial flared portion and a lower ventricular portion, a plurality of prosthetic leaflets, and at least one lining skirt. The prosthesis is configurable or otherwise sizable to fit in the MSML delivery and implantation system and to subsequently be selectively expanded to an operative size and position once deployed within the annulus. A portion of the prosthesis can be configured to couple with dual guiding and fixation (DGF) members to guide and fix the prosthesis to the annulus. In one aspect, the MSML delivery and implantation system includes a main docking system, a DGF member delivery system, and a valve housing, positioning, and locking system.

A delivery system for delivering an endovascular prosthesis is disclosed. A handle assembly is disposed at the distal end of the delivery system. The handle assembly includes a main handle and a second handle disposed at least partially on the main handle and rotationally moveable relative to the main handle. A trigger wire release mechanism is operatively coupled to the second handle. A sheath is operatively coupled to the second handle, such that rotation of the second handle relative to the main handle retracts the sheath in a distal direction. Rotation of the handle also moves the trigger wire release mechanism from a first position to a second position to retract one or more trigger wires.