A system includes an adjustable implant configured for implantation internally within a subject and includes a permanent magnet configured for rotation about an axis of rotation, the permanent magnet operatively coupled to a drive transmission configured to alter a dimension of the adjustable implant. The system includes an external adjustment device configured for placement on or adjacent to the skin of the subject having at least one magnet configured for rotation, the external adjustment device further comprising a motor configured to rotate the at least one magnet and an encoder. Rotation of the at least one magnet of the external adjustment device effectuates rotational movement of the permanent magnet of the adjustable implant and alters the dimension of the adjustable implant. Drive control circuitry is configured to receive an input signal from the encoder.

A gastric restraining device for treating excessive weight or obesity in mammals. The gastric restraining device includes an elastomeric sheet configured to be placed around a stomach of a mammal, an ablation device attached to the elastomeric sheet, the ablation device configured to emit energy toward an outer surface of the stomach when the elastomeric sheet is placed around the stomach, and an energy device coupled to the ablation device to generate the energy and to transfer the energy to the ablation device.

Devices, system and methods for deforming body channels are disclosed herein. At least some embodiments described may be used to deform a body channel so as to decrease or prevent the normal intrachannel flow of material within the body channel. Such deformation may be used to treat such maladies as Gastroesophageal Reflux Disease.

A gastric restraining device for treating excessive weight or obesity in mammals. The gastric restraining device includes an elastomeric sheet configured to be placed around a stomach of a mammal, an ablation device attached to the elastomeric sheet, the ablation device configured to emit energy toward an outer surface of the stomach when the elastomeric sheet is placed around the stomach, and an energy device coupled to the ablation device to generate the energy and to transfer the energy to the ablation device.

An inflatable, adjustable gastric band includes a flexible, hollow, resilient band; and a flexible inflation tube connected to the band and complementary closing means that are capable of mutually engaging so as to lock a ring in a closed position. The ring formed by bringing the distal end and the proximal end of the band together into a slipknot. The hollow band has, in an inoperative position, a preformed curved portion which is extended, by a substantially rectilinear portion, from the proximal end area thereof to the free distal end of the band. The substantially rectilinear portion being suitable for facilitating the insertion of the proximal end of the tube through the loop(s) of the band, and in that the hollow band has, on the outer wall thereof, two loops, said loops being arranged on the substantially rectilinear portion of the hollow band.

The present invention relates to a nano-enhanced device for substance transfer between the device and a tissue. The device comprises a substrate with substantially aligned carbon nanotubes anchored within the substrate, and with at least one end of the carbon nanotubes protruding from the substrate. The protruding nanotube ends may be coated with a drug for delivery of the drug into body tissue. The present invention may be incorporated into an angioplasty catheter balloon or into a patch that is worn on the skin. The carbon nanotubes can be grouped in clusters to effectively form nano-needles which can transfer fluid to or from the subdermal tissue. The nano-needles can be used in conjunction with a sensor to ascertain body fluid information such as pH, glucose level, etc.

The invention relates to an occlusive cuff for selectively occluding an anatomical duct. The occlusive cuff has a band suited to surrounding an anatomical duct, provided with a closing device suited to maintaining the band wound upon itself over a determined length and an inflatable reservoir arranged on an inner face of the band. The cuff is characterised in that the inflatable reservoir extends over only a part of the length of the band, another part of the length defining a free inner surface of the band configured to form a bearing zone for the anatomical duct, such that when the band is maintained wound upon itself by the closing device, the inflatable reservoir is opposite said free inner surface of the band.

The present disclosure provides for wirelessly actuated soft robotic undulating pumps designed to efficiently transport both viscous fluids and solid cargos in human patients, methods of manufacturing a peristalsis-producing stent, and systems including a pair of soft magnetic sheets and a magnetic actuator configured to produce a magnetic field which generates complementary undulation of the pair of soft magnetic sheets. In an aspect, the pair of soft magnetic sheets can have at least a first soft magnetic sheet and a second soft magnetic sheet, and wherein a magnetization profile of the first soft magnetic sheet is coordinated with a magnetization profile of the second soft magnetic sheet.

An apparatus includes a plurality of beads. Each bead includes a housing and a magnet positioned within the housing. The apparatus also includes a plurality of interconnection elements. Each interconnection element movably joins together a corresponding pair of beads. The plurality of beads and the plurality of interconnection elements are sized and configured to form an expandable loop around an anatomical structure in a patient. The apparatus further includes a decoupling element. The decoupling element is positioned along the loop and is configured to selectively release a first portion of the loop from a second portion of the loop in response to application of a threshold force to the at least one decoupling element in a circumferential direction relative to the loop.

A bariatric clamp may include substrate members overmolded in polymer forming first and second elongated portions, a bight portion having a flexible hinge, one or more inflatable portions disposed at least partially along interior sections of the first and second elongated portions; and a port coupled to at least one of the inflatable portions and configured to adjust inflation of the inflatable portions. The inflatable portions are provided to assist in retaining the clamp in a closed position to partition the stomach and to adjust a pressure of the clamp when partitioning the stomach.