The invention relates to an apparatus for a laser-assisted eye-surgery treatment system, comprising a first image-acquisition unit that is designed to acquire a first image (39) of an eye to be treated. The apparatus further comprises a computer arrangement which is designed to detect at least one first feature (40) of the eye by means of image processing of the first image, and to determine a position and an orientation of the first feature in a coordinate system (S) of the treatment system. The computer arrangement is also designed to determine a position and an orientation of an incision (66) to be produced in the eye in the coordinate system (S) of the treatment system as a function of the determined position and orientation of the first feature (40) in the coordinate system and as a function of a previously determined relative position and orientation of at least one second feature (64) of the eye with respect to the first feature (40).

An ophthalmic laser surgical system uses a confocal detector assembly to continuously detect a confocal signal during laser treatment, and based on the confocal signal, detects in real time a loss of tissue contact with the patient interface (PI) output surface. The detection is partly based on the change of reflectivity at the PI output surface when the optical interface changes from a lens-tissue interface to a lens-air interface. The behavior of the confocal signal upon loss of tissue contact is dependent on the treatment laser scan pattern being performed at the time of tissue contact loss. Thus, different confocal signal analysis algorithms are applied to detect tissue contact loss during different scans, such as the bed cut and side cut for a corneal flap. The real time confocal signal may also be used during eye docking to detect the establishment of tissue contact with the PI output surface.

A system for ophthalmic surgery includes a laser source configured to deliver an ultraviolet laser beam comprising laser pulses having a wavelength between 320 nm and 370 nm to photodecompose one or more intraocular targets within the eye with chromophore absorbance. The pulse energy, the pulse duration, and the focal spot are such that an irradiance at the focal spot is sufficient to photodecompose the one or more intraocular targets without exceeding a threshold of formation of a plasma and an associated cavitation event. An optical system operatively coupled to the laser source and configured to focus the ultraviolet laser beam to a focal spot and direct the focal spot in a pattern into the one or more intraocular targets. The optical system focuses the laser beam at a numerical aperture that provides for the focal spot to be scanned over a scan range of 6 mm to 10 mm.

A patient interface includes an eye interface device, a scanner, a first support assembly, and a beam source. The eye interface device is configured to interface with an eye of a patient. The scanner is configured to be coupled with the eye interface device and operable to scan an electromagnetic radiation beam in at least two dimensions in an eye interfaced with the eye interface device. The scanner and the eye interface device move in conjunction with movement of the eye. The first support assembly supports the scanner so as to accommodate relative movement between the scanner and the first support assembly parallel so as to accommodate movement of the eye. The beam source generates the electromagnetic radiation beam. The electromagnetic radiation beam propagates from the beam source to the scanner along an optical path having an optical path length that varies in response to movement of the eye.

The present invention relates to a method for controlling an eye surgical laser for the separation of a volume body with predefined interfaces from a human or animal cornea, comprising controlling the laser by means of a control device such that it emits pulsed laser pulses in a predefined pattern into the cornea, wherein the interfaces of the volume body to be separated are defined by the predefined pattern and the interfaces are generated by means of photodisruption, wherein the interfaces of the volume body are determined such that a pathological and/or unnaturally altered area within the stroma of the cornea is enclosed. Furthermore, the invention relates to a treatment device with at least one eye surgical laser for the separation of a predefined corneal volume with predefined interfaces of a human or animal eye by means of photodisruption and at least one control device for the laser or lasers, which is formed to execute the steps of the method according to the invention.

In certain embodiments, a device comprises a laser device and a control computer. The laser device directs a laser beam with laser energy through an outer portion of an eye to a target portion of the eye. The control computer receives an optical density measurement of the outer portion, determines the laser energy according to the optical density measurement, and instructs the laser device to direct the laser beam with the laser energy through the outer portion of the eye to the target portion of the eye.

The planning device for determining control data for a treatment device enables surgical tattooing of the cornea of an eye. Based on the measurement data and functional data introduced, a substantially annular surface is defined, which is located inside the cornea and which is delimited by a circular internal edge with an interior diameter and by a circular external edge with an exterior diameter. The annular surface has a distance and an incline with regard to the surface of the cornea, and for this annular surface, a set of control data for controlling the laser device is generated which defines a pattern of target points in the cornea with perforation zones partially or completely intersecting. Upon application of the pulsed laser beam, the tissue of the cornea is cut, and the external edge of the annular surface has a constant distance relative to the external edge of the iris.

In certain embodiments, a system for controlling a position of a focal point of a laser beam comprises a beam expander, a scanner, an objective lens, and a computer. The beam expander controls the focal point of the laser beam and includes a mirror and expander optical devices. The mirror has a surface curvature that can be adjusted to control a z-position of the focal point. The expander optical devices direct the laser beam towards the mirror and receive the laser beam reflected from the mirror. The scanner receives the laser beam from the beam expander and manipulates the laser beam to control an xy-position of the focal point. The objective lens receives the laser beam from the scanner and directs the beam towards the target. The computer receives a depth instruction, and sets actuation parameters to control the surface curvature of the mirror according to the depth instruction.

Embodiments of this invention generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for photorefractive keratectomy. In an embodiment, an ophthalmic surgical laser system comprises a laser source generating a pulsed laser beam and a laser delivery system delivering the pulsed laser beam to a cornea of an eye. A patient interface couples to and constrains the eye relative to the laser delivery system. A controller controls the laser delivery system to perform an anterior surface volume dissection on the cornea.

The present invention discloses a device suitable for delivery of a fluid composition to an eye, especially therapeutic compositions, comprising: a hollow needle with a bore having a proximal end and a distal end, said distal end configured to pass into a passage in a sclera of an eye, said bore configured to function as a conduit for a fluid from said proximal end to said distal end, and a solid separator having a distal tip, configured to move inside said bore of said hollow needle allowing said distal tip of said separator to protrude from said distal end of said needle.