An apparatus for treatment of an eye comprises a source of pulsed laser radiation, and a control device for controlling a focus of the laser radiation to generate an incision figure. The incision figure defines a corneal flap, a first auxiliary channel and a second auxiliary channel. The corneal flap is connected to adjoining corneal tissue in a hinge region, and has a flap underside parted-off from adjoining corneal tissue by a bed incision. The first auxiliary channel extends from the hinge region to an outer surface of the eye and is adapted to remove gases that develop during the generation of the bed incision. The second auxiliary channel extends along an edge of the bed incision, is connected to the first auxiliary channel, and extends beyond the hinge region. The control device is configured to generate the second auxiliary channel prior to the bed incision.

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

The vision correction apparatus according to the present invention comprises: a cutting-off beam generating unit that generates a cutting-off beam for cutting off a part of the cornea for a vision correction surgery, a welding beam generating unit that generates a welding beam having a wavelength in a near-infrared band for welding a part of the cut cornea by irradiating the welding beam to the cut position of the cornea, a beam delivery unit that delivers the cutting-off beam and the welding beam to the cut position of the cornea, an image unit that obtains image information on the cut position of the cornea, and a control unit that controls an irradiation position of the welding beam based on the cut position information of the cornea obtained by the image unit.

The invention provides an excimer laser system including a means for calibrating laser output to compensate for increased variation in laser optical fibers.

Histatins are used to treat ocular surface diseases such as dry eye. For example, histatins are included in eye drops, eye gels, ointment, glue, or embedded in (polymer) contact lenses. In some embodiments, peptide fragments from at least two different histatins are used. In some other embodiments, an additional therapeutic (nonhistatin) agent is used in combination with the histatins. In some embodiments, histatin 5 or fragments of histatin 5 are used in combination with an additional therapeutic (non histatin) agent. Histatins may alternatively be included as preservatives in ophthalmic preparations.

The present invention relates to a femtosecond laser ophthalmological apparatus and method that creates a flap on the cornea for LASIK refractive surgery or for other applications that require removal of corneal and lens tissue at specific locations, such as in corneal transplants, stromal tunnels, corneal lenticular extraction and cataract surgery. The femtosecond laser is transferred from the main cabinet to a hand piece module via a rotating mirror set module. In the hand piece, the femtosecond laser beam is scanned and guided to the patient's eye. The ablation pattern is based on dividing the area of the ablation area into a matrix grid made up of cells. Predetermined ablation pattern is completed in an individual cell before moving on to the next cell until ablation is complete in the entire matrix grid mapped on the ablation area.

In certain embodiments, a device comprises a laser device and a control computer. The laser device directs a laser beam with laser energy through an outer portion of an eye to a target portion of the eye. The control computer receives an optical density measurement of the outer portion, determines the laser energy according to the optical density measurement, and instructs the laser device to direct the laser beam with the laser energy through the outer portion of the eye to the target portion of the eye.

A system for forming corneal implants includes a first cutting apparatus configured to cut a donor cornea and form a portion of corneal tissue. The donor cornea includes an anterior surface and a posterior surface. The first cutting apparatus is configured to cut the donor cornea along an axis extending between the anterior surface and the posterior surface. The system also includes a second cutting apparatus configured to form a plurality of lenticules from the portion of corneal tissue by making, to the portion of corneal tissue, a series of cuts transverse to the axis. Corneal tissue between consecutive cuts by the second cutting apparatus provides a corresponding lenticule to be shaped for a corneal implant. A distance between the consecutive cuts defines a thickness for the corresponding lenticule.

A marker device for producing paint marks on an eye is disclosed. The marker device comprises a handling unit and a marker unit coupled to the handling unit for rotation with respect to the handling unit about a rotational axis. The marker unit includes at least two spaced apart marking surfaces and has a rotationally symmetric distribution of weight with respect to the rotational axis. A coupling between the handling unit and the marker unit permits the marker unit to rotate, due to gravity, relative to the handling unit into an equilibrium position.

A method of inserting and securing a corneal implant in engaging and fluid-flow limiting relation to the posterior cornea, such as to treat edema. The method includes securing a corneal implant in fluid flow limiting relation to the posterior cornea through an incision in the eye and securing it in place by a variety of steps such as corneal insertion or laser bonding, and preferably by inserting a removable corneal implant including a central region and a plurality of retention member(s) disposed on the periphery thereof into the eye so as to releaseably and removably engage a portion of the eye and thereby retain the corneal implant in abutting and engaging relation with the posterior cornea. The retention members of the corneal implant may also comprise haptic leg(s) extending from the central region.