A system and method for performing ophthalmic surgery using an ultra-short pulsed laser is provided. The system includes a laser engine configured to provide an ultra-short pulsed laser beam, optics configured to direct the laser beam to an undocked eye of a patient, an eye tracker configured to measure five degrees of freedom of movement of the undocked eye, an optical coherence tomography module configured to measure depth of the undocked eye, and a controller configured to control laser beam position on the undocked eye toward a desired laser pattern based on depth and the five degrees of freedom of movement of the undocked eye. Adaptive optics are also provided. Also disclosed are a scleral ring including fiducial markings and a compliant contact lens and fluid tillable contact lens configured to facilitate ultra-short pulsed laser surgery while reducing or eliminating eye docking requirements.

A method that includes illuminating an eye with light at a first time and a second time and generating a first image of the eye based on the light that illuminates the eye at the first time. The method includes generating a second image of the eye based on the light that illuminates the eye at the second time. The method further includes positioning a laser source relative to the eye, wherein the laser source generates a therapeutic laser beam to be directed to the eye, wherein the first time is just prior to the therapeutic laser beam being directed to the eye and the second time is prior to the first time. The method further includes correcting orientation of the laser source relative to the eye based on a correlation function that is defined for the first and second images of the eye.

In a laser cataract procedure that also corrects for astigmatism, an iris registration method compares an iris image of a patient's eye taken when the eye is not docked to a patient interface device with an iris image of the same eye that is docked to the patient interface, to calculate a rotation angle between the two images. The astigmatism axis of the eye is measured when the eye is not docked, and the measured axis is rotated by the calculated rotation angle to obtain a rotated astigmatism axis relative to the iris image of the docked eye. The laser cataract procedure is performed based on the rotated astigmatism axis. The rotation angle is calculated by optimizing a transformation that transforms the undocked iris image to match the docked iris image, where the transformation includes a dilation factor that accounts for different pupil dilation of the two iris images.

Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or ocular tissues is performed to address various types of vision correction, and the laser induced changes to the refractive index avoid ablation and removal of the optical polymer materials while minimizing scattering losses.

A system for guiding an ophthalmic procedure is disclosed. The system includes a housing assembly with a head unit configured to be at least partially directed towards a target site in an eye. An optical coherence tomography (OCT) module and stereoscopic visualization camera are at least partially located in the head unit and configured to obtain a first set and a second set of volumetric data, respectively. A controller is configured to register the first set and second set of volumetric data to create a third set of registered volumetric data. The third set and second set of registered volumetric data are rendered, via a volumetric render module, to a first and second region. The first region and the second region are overlaid to obtain a shared composite view of the target site. The controller is configured to extract structural features and/or enable visualization of the target site.

A method is disclosed for determining a current position of a patient interface of an eye surgical laser for an eye relative to an optical axis of a laser beam of a treatment apparatus. The method includes determining a target position of the patient interface relative to the optical axis, positioning the patient interface in a preset area in front of the optical axis, illuminating the patient interface by means of an illumination device, capturing a Purkinje image by means of the optical capturing device, comparing the captured Purkinje image to the optical axis and determining the current position of the patient interface depending thereon, comparing the current position to the target position and with a deviation, and outputting a control signal to a control device of the treatment apparatus. A treatment apparatus, a computer program and a computer-readable medium are disclosed for carrying out the method.

A method for controlling an eye surgical laser is disclosed for the separation of a volume body. The method includes determining a target position of a pupil relative to a laser beam and determining an optical zone with a treatment center on interfaces relative to an optical axis of the laser beam, determining a transition zone at the volume body as an extension of the interface, capturing a current actual position of the pupil, determining a deviation between the target position and the actual position, and decentering the determined optical zone relative to the optical axis depending on the determined deviation such that the edge of the volume body is generated concentrically to the optical axis and the optical zone is generated concentrically to the determined treatment center and within the transition zone. Further disclosed are a treatment apparatus, a computer program and computer-readable medium capable of performing the method.

A method is disclosed for determining a current position of an eye of a patient relative to an optical axis of a laser beam of a treatment apparatus. The method includes presetting a criterion characterizing the eye, determining a first target position of the eye relative to the optical axis, positioning a patient interface in a preset area in front of the optical axis, illuminating the eye during an approaching procedure of the patient interface to the eye, capturing a Purkinje image, which is associated with a cornea of the eye, by means of an optical capturing device during the approaching procedure, comparing the captured Purkinje image to the optical axis and determining the current position of the eye depending thereon, comparing the current position to the target position and with a deviation, outputting a control signal to a control device of the treatment apparatus.

The disclosure provides a system that may: receive data associated with multiple locations associated with a cornea of an eye; adjust at least one lens, based at least on diameter information of the data associated with at least one of the multiple locations, to set a diameter of a laser beam; and for each location of the multiple locations: determine if the eye has changed from a first position to a second position; if the eye has not changed from the first position to the second position, adjust, based at least on the location, at least one mirror; if the eye has changed from the first position to the second position, adjust, based at least on the location and based at least on the second position, the at least one mirror; produce the laser beam; and direct the laser beam to the location for a period of time.

The present disclosure provides a laser treatment system that includes an optical coherence tomography (OCT) imaging system that generates a plurality of profile depth scans and executes instructions on a processor to detect a position, a volume, or a combination thereof, of a media opacity in an eye based on the plurality of profile depth scans. The system further includes a three-dimensional (3D) eye tracker that executes instructions on the processor to track the position, the volume, or a combination thereof, of the media opacity in the eye based on the plurality of profile depth scans. The system also includes a laser system that includes a treatment laser and that precisely targets a plurality of ultra-short laser pulses generated by the treatment laser at the media opacity in the eye to at least partially remove the media opacity.