A laser system calibration method and system are provided. In some methods, a calibration plate may be used to calibrate a video camera of the laser system. The video camera pixel locations may be mapped to the physical space. A xy-scan device of the laser system may be calibrated by defining control parameters for actuating components of the xy-scan device to scan a beam to a series of locations. Optionally, the beam may be scanned to a series of locations on a fluorescent plate. The video camera may be used to capture reflected light from the fluorescent plate. The xy-scan device may then be calibrated by mapping the xy-scan device control parameters to physical locations. A desired z-depth focus may be determined by defining control parameters for focusing a beam to different depths. The video camera or a confocal detector may be used to detect the scanned depths.

Apparatus to treat an eye comprises an annular retention structure to couple to an anterior surface of the eye. The retention structure is coupled to a suction line to couple the retention structure to the eye with suction. A coupling sensor is coupled to the retention structure or the suction line to determine coupling of the retention structure to the eye. A fluid collecting container can be coupled to the retention structure to receive and collect liquid or viscous material from the retention structure. A fluid stop comprising a porous structure can be coupled to an outlet of the fluid collecting container to inhibit passage of the liquid or viscous material when the container has received an amount of the liquid or viscous material. The coupling sensor can be coupled upstream of the porous structure to provide a rapid measurement of the coupling of the retention structure to the eye.

Intraocular pressure in an eye is reduced by delivering a high resolution optical coherence tomography (OCT) beam and a high resolution laser beam through the cornea, and the anterior chamber into the irido-corneal angle along an angled beam path. The OCT beam provides OCT imaging for surgery planning and monitoring, while the laser beam is configured to modify tissue or affect ocular fluid by photo-disruptive interaction. In one implementation, a volume of ocular tissue within an outflow pathway in the irido-corneal angle is modified to create a channel opening in one or more layers of the trabecular meshwork. In another implementation, a volume of fluid in the Schlemm's canal is affected by the laser to bring about a pneumatic expansion of the canal. In either implementation, resistance to aqueous flow through the eye is reduced.

In certain embodiments, an ophthalmic laser surgical system for imaging and treating a target in an eye includes an optical coherence tomography (OCT) device that: directs an imaging beam towards the eye; generates three-dimensional (3D) image data from the imaging beam reflected from the eye; and generates two-dimensional (2D) enface images from the 3D image data. The 2D enface images include a target enface image imaging the target in the eye and a retinal enface image imaging a shadow cast by the target onto the retina. An xy-scanner directs the imaging beam along an imaging beam path towards the eye, and directs a laser beam from the laser device along a laser beam path aligned with the imaging beam path towards the eye. A computer compares the target of the target enface image and the shadow of the retinal enface image to confirm the presence of the target.

In certain embodiments, an ophthalmic laser surgical system for imaging and treating a target in an eye includes an imaging system. The imaging system includes a scanning laser ophthalmoscope (SLO) device and an optical coherence tomography (OCT) device. The SLO device generates SLO images, and the OCT device generates OCT images. The SLO device and the OCT device share a scanning system and a light detector. The scanning system scans SLO and OCT imaging beams within the eye. The light detector detects the SLO and OCT imaging beams reflected from the eye and generates SLO and OCT signals in response to detecting the imaging beams.

In certain embodiments, an ophthalmic laser surgical system for imaging and treating a target in an eye includes a digital micromirror device (DMD) confocal microscope, a laser device, and a computer. The DMD confocal microscope generates of images of the eye and includes a light source, a DMD device, and an image sensor. The light source provides a microscope imaging beam. The DMD device directs the microscope imaging beam along an imaging path towards the eye, receives the microscope imaging beam reflected from the eye, and rejects light of the reflected microscope imaging beam that is not from an image plane to scan the microscope imaging beam. The image sensor detects the scanned microscope imaging beam to generate the images of the eye. The laser device directs a laser beam along a laser beam path towards the target in the eye.

Methods are provided for performing a surgical procedure using optical coherence tomography (OCT) including extracting lenticular material from within a capsular bag of the eye of a patient; placing a replacement lens within the capsular bag after extraction of the lenticular material from the capsular bag; acquiring a plurality of OCT images that visualize the placement of the replacement lens within the capsular bag; and determining from the plurality of OCT images a degree of contact of the posterior surface of the replacement lens with the posterior portion of the capsular bag.

Embodiments of this invention generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incision. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to form a top lenticular incision and a bottom lenticular incision of a lens in the subject's eye, or just a bottom lenticular incision.

An ophthalmic apparatus includes an interference optical system, an optical scanner controller, and a correction controller. The interference optical system includes an astigmatism correction optical member and an optical scanner, and is configured to split light from a light source into reference light and measurement light, to irradiate the measurement light onto the subject’s eye via the astigmatism correction optical member and the optical scanner, and to detect interference light between returning light of the measurement light from the subject’s eye and the reference light. The optical scanner controller is configured to control the optical scanner so as to deflect the measurement light in a horizontal direction and a vertical direction on a plane perpendicular to an optical axis of the interference optical system. The correction controller is configured to control the astigmatism correction optical member so as to correct astigmatism based on a detection result of the interference light obtained by the interference optical system.

Systems and methods automatically locate optical surfaces of an eye and automatically generate surface models of the optical surfaces. A method includes OCT scanning of an eye. Returning portions of a sample beam are processed to locate a point on the optical surface and first locations on the optical surface within a first radial distance of the point. A first surface model of the optical surface is generated based on the location of the point and the first locations. Returning portions of the sample beam are processed so as to detect second locations on the optical surface beyond the first radial distance and within a second radial distance from the point. A second surface model of the optical surface is generated based on the location of the point on the optical surface and the first and second locations on the optical surface.