A laser system calibration method and system are provided. In some methods, a calibration plate may be used to calibrate a video camera of the laser system. The video camera pixel locations may be mapped to the physical space. A xy-scan device of the laser system may be calibrated by defining control parameters for actuating components of the xy-scan device to scan a beam to a series of locations. Optionally, the beam may be scanned to a series of locations on a fluorescent plate. The video camera may be used to capture reflected light from the fluorescent plate. The xy-scan device may then be calibrated by mapping the xy-scan device control parameters to physical locations. A desired z-depth focus may be determined by defining control parameters for focusing a beam to different depths. The video camera or a confocal detector may be used to detect the scanned depths.

A system for determining a vision treatment for an eye of a patient is provided which comprises a memory configured to store programmed instructions and data. The system also comprises a processor in communication with the memory. The processor is configured to receive an original target profile for the eye of the patient. The processor is also configured to obtain a cut-off spatial domain kernel filter and convolve the original target profile with the cut-off spatial domain kernel filter to provide a convolved target profile. The processor is further configured to determine the vision treatment based on the convolved target profile.

A laser system calibration method and system are provided. In some methods, a calibration plate may be used to calibrate a video camera of the laser system. The video camera pixel locations may be mapped to the physical space. A xy-scan device of the laser system may be calibrated by defining control parameters for actuating components of the xy-scan device to scan a beam to a series of locations. Optionally, the beam may be scanned to a series of locations on a fluorescent plate. The video camera may be used to capture reflected light from the fluorescent plate. The xy-scan device may then be calibrated by mapping the xy-scan device control parameters to physical locations. A desired z-depth focus may be determined by defining control parameters for focusing a beam to different depths. The video camera or a confocal detector may be used to detect the scanned depths.

An ophthalmic surgical system includes a chassis comprising a laser source. The system includes a gantry coupled to the chassis. The position of the gantry is adjustable. The system includes a reference interface coupled to the gantry. The reference interface comprises an attachment interface at a distal portion of the reference interface, configured to couple to a patient interface for docking with an eye. The reference interface is configured to move to a first plate position proximal to the chassis and a second plate position distal from the chassis. The system further includes an optical head unit coupled to the reference interface. The optical head unit comprises a laser scanner and a beam splitter. The optical head unit is configured to move to a first head unit position near a proximal end of the reference interface and a second head unit position which is a lockable surgical position near a distal end of the reference interface.

An ophthalmological device (10) for the treatment of corneal diseases such as keratoconus and glaucoma, comprises a moulding head (12), a suction body (14) and a UV lamp (15). The moulding head (12) has a hollow cylindrical configuration and includes a rigid moulding lens (18) for shaping the cornea of an eye (11) of a patient. The lens is curved and defines a plurality of apertures therein. The suction body (14) has a hollow cylindrical configuration. The lamp (15) is fitted to the suction body. Moulding head (12) and suction body (14) together define a chamber (32) from which air is evacuated so as to induce a partial vacuum within the chamber (32) for attracting the cornea onto the lens (18). A photo-sensitizer is applied to the eye and while the cornea is held against the mould, it is irradiated with UV light by lamp (15) so as to cross-link collagen fibres in the cornea.

Deconvolution systems and methods based on cornea smoothing can be used to obtain an ablation target or treatment shape that does not induce significant high-order aberrations such as spherical aberration. Exemplary ablation targets or treatment shapes can provide a post-operative spherical aberration that is equal to or below a naturally occurring amount of spherical aberration.

Deconvolution systems and methods based on cornea smoothing can be used to obtain an ablation target or treatment shape that does not induce significant high-order aberrations such as spherical aberration. Exemplary ablation targets or treatment shapes can provide a post-operative spherical aberration that is equal to or below a naturally occurring amount of spherical aberration.

The invention relates to treatment apparatus (10) for correcting a refractive error of an eye (12) that includes a laser device (14) for separating corneal tissue by means of laser radiation (16); a control device (18) designed to control the laser device (14) to emit the laser radiation (16) for cutting out and/or ablating a volume (24) out of the surface (26) of the cornea (22) of the eye (12) in dependency on a measured pachymetry of the cornea (22) and the refractive error of the eye (12), whereby the cut-out and/or ablated volume (24) in the surface (20) of the cornea (22) results in a shape of a closed ring, a partial ring, a crescent or a crescent shaped closed ring. A method for controlling such an apparatus for correcting a refractive error of an eye, and to a protective mask for an eye are also provided.

Treatment validation techniques include generating a modified treatment target from an original treatment target using a modification process, and comparing induced aberrations provided by the original and modified treatment targets, so as to verify the modified treatment target or the modification process. In some cases, a modification process may include a deconvolution process, a low pass filter process, a scaling process, or an adjustment process. The induced aberrations may include high order aberrations, such as spherical aberration.

Laser assisted cataract surgery methods and devices utilize one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may be applied to the anterior lens capsule to facilitate laser thermal separation of tissue along a treatment beam path on the lens capsule. Relative or absolute reflectance from the eye, and optionally from a surgical contact lens, may be measured to confirm and optionally quantify the presence of the light absorbing agent, before the treatment beam is applied. Such measurements may be used to determine that sufficient light absorbing agent is present in the lens capsule so that transmission of the treatment beam through the capsule will be below a predetermined threshold deemed safe for the retina and other interior portions of the eye, and may also be used to determine that sufficient light absorbing agent is present to result in complete laser thermal separation of the anterior capsule along the treatment beam path. Visualization patterns produced with one or more target laser beams may be projected onto the lens capsule tissue to aid in the capsulorrhexis procedure. In addition or alternatively, virtual visualization patterns may presented on a display integrated with a laser assisted cataract surgery device to aid in the procedure. The visual axis of the eye may be determined, during surgery for example, with a laser beam on which the patient is fixated. The orientation of a toric IOL may be assessed during or after placement by observing the reflection from the back of the eye of a laser beam on which the patient is fixated. The devices disclosed herein may be attached to or integrated with microscopes.