Control apparatus (1) for controlling the dosing of a chromophoric agent (100) in a corneal tissue (101), comprising: a first source (2) for irradiating the corneal tissue (101) with at least a first electromagnetic radiation (21); first measurement means (3) for measuring a first spectroscopic parameter (31), such as the fluorescence intensity or the diffused intensity; a processing unit (4) configured to calculate a factor (C) representative of the concentration of the chromophoric agent (100) inside the corneal tissue (101) in response to at least two measurements of the first spectroscopic parameter (31), of which one measurement is indicative of the energy perturbation caused by the first electromagnetic radiation (21) in the corneal tissue (101) without the chromophoric agent (100) and the further measurement is indicative of the energy perturbation caused by the first electromagnetic radiation (21) in the corneal tissue (101) containing the chromophoric agent (100).

Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or optical tissues is performed to address various types of vision correction.

The present invention relates to a method for monitoring a functionality of an apparatus (100) for refractive surgery on an eye (2) using a laser beam (4). The method comprises a determination of at least one parameter of a preparation and/or implementation of a method for refractive surgery, wherein the preparation and/or the implementation of the method are carried out at least in part by the apparatus for refractive surgery using the laser beam (4). Further, the method comprises an analysis of the functionality of the apparatus (100) on the basis of the determined parameter of the preparation and/or the implementation of the method for refractive surgery. In this case, the at least one parameter characterizes one or more of the following properties of the preparation and/or implementation of the method for refractive surgery: a provision of the laser beam (4) by the apparatus (100); an effect on the eye (2) by the apparatus (100); an external influence on the preparation and/or the implementation of the method for refractive surgery from outside of the apparatus (100); and a suitability of the effect on the eye (2) by the laser beam (4) for the further method of the refractive surgery on the eye (2).

Moreover, the invention relates to a control unit (14) and an apparatus (100) for refractive surgery on an eye (2).

The invention relates to a method for controlling an ophthalmological laser (12) of a treatment apparatus (10) for the treatment of a human or animal eye (16), comprising controlling the laser (12) by means of a control device (18) of the treatment apparatus (10) such that it emits pulsed laser pulses (20) in a shot sequence in a preset pattern into the eye (16), wherein the individual laser pulses interact with a tissue (14) of the eye for the treatment of the eye (16), wherein a space-filling curve is preset for the pattern for treating the tissue (14).

A planning device that generates control data for a treatment apparatus which produces at least one cut surface in the cornea by application of a laser device. The invention further relates to a treatment apparatus having a planning device of the aforementioned type. The invention further relates to a method for generating control data for this treatment apparatus, and also to a method for eye surgery, at least one cut surface being produced in the cornea by application of a treatment apparatus with a laser device. The planning device has a calculation application for defining corneal cut surfaces, including a lenticule cut and a cap cut, the incision being controlled by the control data such that mutually corresponding locations of the lenticule cut and cap cut are impinged by laser pulses at substantially the same time interval.

Methods for treating presbyopia in a patient's eye involve inducing spherical aberration in a central area of the pupil. In embodiments, refractive properties of an eye are measured to obtain a baseline refractive correction. A lens for wearing on the eye is provided to create spherical aberration or a distribution of spherical aberrations beyond the baseline refractive correction in the central area of the pupil. The central area of the pupil has a diameter of between 1.5 mm and 4.0 mm and has negligible spherical aberration without the treatment.

An imaging system includes an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The eye interface device interfaces with an eye. The scanning assembly supports the eye interface device and scans a focal point of an electromagnetic radiation beam within the eye. The beam source generates the electromagnetic radiation beam. The free-floating mechanism supports the scanning assembly and accommodates movement of the eye and provides a variable optical path for the electronic radiation beam and a portion of the electronic radiation beam reflected from the focal point location. The variable optical path is disposed between the beam source and the scanner and has an optical path length that varies to accommodate movement of the eye. The detection assembly generates a signal indicative of intensity of a portion of the electromagnetic radiation beam reflected from the focal point location.

An imaging system includes an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The eye interface device interfaces with an eye. The scanning assembly supports the eye interface device and scans a focal point of an electromagnetic radiation beam within the eye. The beam source generates the electromagnetic radiation beam. The free-floating mechanism supports the scanning assembly and accommodates movement of the eye and provides a variable optical path for the electronic radiation beam and a portion of the electronic radiation beam reflected from the focal point location. The variable optical path is disposed between the beam source and the scanner and has an optical path length that varies to accommodate movement of the eye. The detection assembly generates a signal indicative of intensity of a portion of the electromagnetic radiation beam reflected from the focal point location.

A treatment apparatus for operatively correcting myopia or hyperopia in an eye includes a laser device controlled by a control device and that separates the corneal tissue by applying a laser beam. The control device controls the laser device to emit the laser beam into the cornea such that a lenticule-shaped volume is isolated in the cornea. The control device, when controlling the laser device, predefines the lenticule-shaped volume such that the volume has a minimum thickness of between 5 and 50 μm. For myopia correction, the minimum thickness occurs on the edge of the volume, and for hyperopia correction the minimum thickness occurs in the region of the visual axis.

A device for isolating a lenticle in the cornea of an eye. The device includes: a laser beam source to emit pulsed laser radiation having a pulse frequency of 1.2 MHz to 10 MHz, a pulse energy of 1 nJ to 200 nJ and a wavelength penetrating the cornea; a beam-forming unit having beam optics with an image field and that bundles pulsed laser radiation into a focus located inside the image field, and which has a maximum diameter of less than 3 μm; a beam-deflection unit shifting the focus in the cornea and inside the image field, the focus moving along a path when the image field is resting; and a control unit to control the source and the beam-forming unit to isolate the lenticle by specifying the path. The lenticle is delimited by a cut surface which is curved with regard to a front surface of the cornea.