A vitrectomy needle comprises a hollow needle with a distal end for insertion into the vitreous body of an eye for performing a vitrectomy. The vitrectomy needle further comprises a laser light guide guided in the hollow needle to the distal end and has a light-emitting surface oriented towards the distal end. A cavity is formed between the light-emitting surface and the axially inward-facing surface of the distal end. In the area of the cavity, the wall of the hollow needle has an aperture extending radially with respect to the middle axis (M) of the hollow needle. The vitrectomy needle, has a straight section at the proximal end, the middle axis (M) defining a central axis (Z) in the region of the straight section. The middle axis (M) of the hollow needle may be spaced apart from the central axis (Z) by a predetermined minimum radial distance (R).

In certain embodiments, an illuminating endoprobe system includes one or more light sources, a housing, a vitreous visualization fiber, and a general illumination fiber. The light sources generate a visualization light and an illumination light. The housing receives the visualization and illumination light, and has a probe tip with a probe axis. The vitreous visualization fiber transmits the visualization light through the probe tip. The visualization light has a visualization axis and a visualization beam angle at the probe tip. The general illumination fiber transmits the illumination light through the probe tip. The illumination light has an illumination axis and an illumination beam angle at the probe tip. The illumination beam angle is greater than the visualization beam angle, and the illumination axis is at an offset angle relative to the visualization axis, where the offset angle greater than 5 degrees.

Certain aspects of the present disclosure provide a probe comprising a tube, wherein one or more optical fibers extend at least partially through the tube for transmitting at least one of a laser light and an illumination light from a light source to a target location. A distal end of the tube comprises a flat-walled morphology, and a protective window with a round edge is press-fit to the distal end. The flat-walled morphology of the distal end of the tube has a reduced diametric interference sensitivity, thus allowing a wider range of tolerances between the window and the tube walls for effective press-fitting.

Certain embodiments provide an apparatus comprising a hand-piece, an outer tube coupled to the hand-piece, an inner tube housed within the outer tube and having a distal end coupled to a soft tip and a proximal end coupled to an adapter, a proximal end of the adapter coupled to a distal end of a valve, the valve slidably coupled to the hand-piece, and a core slidably coupled to the hand-piece and having a distal end coupled to a proximal end of the valve. To retract the soft tip, the valve is retracted, causing the adapter, the valve, and the core to slidably retract in a proximal direction in relation to the hand-piece, and to extend the soft tip, the valve is protracted, causing the adapter, the valve, and the core to slidably protract in a distal direction in relation to the hand-piece.

A system for processing a portion in a processing volume of a transparent material by application of focused radiation including a device for generating and an optical system for focusing radiation, with a device for changing the position of the focus of the radiation and a control device. The system includes a controller that controls the ophthalmologic therapy system. The controller is encoded with a scan pattern. The scan pattern includes adjacent strokes with each adjacent stroke having an angle of inclination (α) to the beam axis; and the angle of inclination (α) of the strokes to the beam axis is always larger than or equal to the focal angle (φ) of the focused radiation.

An optical system for a laser therapy instrument for the application of laser radiation on and in the eye, includes a femtosecond laser, an objective. The objective or at least one lens or lens group of the objective is shiftable in the direction of the optical axis being intended for shifting of the focus position from the region of the cornea to the region of the crystalline lens and vice versa. The optical system may include at least two optical assemblies designed for the axial variation of the focus of the therapeutic laser radiation, with the focus variation range Δz differing between the individual assemblies and a changing device, designed for the insertion of any one of these assemblies into the therapeutic laser beam path at a time.

An ophthalmic surgical cutting apparatus for cutting biological material including a handle, an outer tube attached to the handle and having a closed tip, a port formed in a side wall of the outer tube with a cusp formed by two or more intersecting surfaces, and an inner tube slidable within the outer tube and having a longitudinal axis and an open tip. The inner tube is in fluid communication with the handle, and the cusp of the port and the open tip interface during a cutting motion to fracture and cut biological materials and direct cut materials radially inward into the port.

Provided herein is a probe for treating an eye of a patient. In one or more embodiments, the probe includes a body, and a tubular element having a main lumen extending from the body, the tubular element comprising a distal end. The probe further includes a visualization optical fiber within the main lumen, the visualization optical fiber adapted to emit an illumination provided by at least one of a plurality of light sources connected to the visualization optical fiber. In some embodiments, the probe further includes an optical switching system (e.g., a time-division multiplexor) operable with the plurality of light sources, wherein the optical switching system is adapted to independently control each of the plurality of light sources. By providing time-division multiplexing between different surgical light sources, quasi-simultaneous illumination delivery through the same optical path may be achieved.

The invention concerns a dye for use in a method of treating a vitreous opacity-related disease in a subject. The method preferably comprises administering the dye to the vitreous body of an affected eye of the subject; and irradiating at least part of the vitreous opacity, thereby inducing destruction of the vitreous opacity in the subject. The invention further relates to the use of a dye for photodestruction of a vitreous opacity in an eye of a subject, and to a method of photodestruction of a vitreous opacity in an eye of a subject, the method comprising: administering a dye to the vitreous body of the eye of the subject; and irradiating at least part of the vitreous opacity, thereby inducing destruction of the vitreous opacity of the subject.

A surgical probe system comprising a surgical probe having an instrument tip, and at least one motion sensor located within the surgical probe that measures movement and orientation data. The system further includes a processor that is configured to determine movement and orientation of the instrument tip based on the movement and orientation data, and adjust at least one surgical parameter of the surgical probe based on the movement and orientation of the instrument tip to affect a predetermined surgical outcome.