An implantable article comprising a dissolvable sponge derived from the mixture of chitosan, a first polysaccharide and a second polysaccharides. The polysaccharides have different number average molecular weight characteristics to enable the control of the mechanical features of the sponge.

A medical packing device for use within a body cavity of a subject is provided. The medical packing device comprises an absorbent member having at least a first major side surface and at least one depression that is formed in the first major side surface and has a predetermined shape and volume. The at least one depression is defined by a continuous perimeter wall that is formed in the first major side surface and forms a reservoir capable of receiving and retaining a volume of a medicament therein.

An implantable article comprising a dissolvable sponge derived from the mixture of chitosan, a first polysaccharide and a second polysaccharides. The polysaccharides have different number average molecular weight characteristics to enable the control of the mechanical features of the sponge.

An implantable article comprising a dissolvable sponge derived from a mixture of chitosan, a first cellulosic polysaccharide and a second cellulosic polysaccharide. The cellulosic polysaccharides have different number average molecular weight characteristics to enable the control of the mechanical features of the sponge.

The present disclosure provides a biofragmentable sponge, comprising a three-dimensional porous scaffold formed by freeze-drying a mixture of about 5% to about 20% (w/w) of silk protein, about 5% to about 85% (w/w) of a water soluble synthetic polymer or a mixture of water soluble synthetic polymers, and about 10% to about 90% (w/w) of a polysaccharide.

A device for treating nosebleeds includes a mouth insert comprising a horizontally extending elongated portion and a center portion extending downward from a bottom surface of the elongated portion. The center portion comprises a narrower width than the horizontally extending elongated portion and the elongated portion is shaped and dimensioned to be inserted into a buccal cavity of a user's mouth and to fit behind the user's upper lip and in front of the user's upper gums. The center portion is shaped and dimensioned to be positioned only in front of the user's upper front teeth. The center portion comprises a push-structure formed at a bottom end of the center portion and the push-structure comprises a push-surface used for placing a user's tongue or finger and pushing the device upward in order to provide pressure to the user's nose.

A plug for insertion into the nose or ear of a subject, comprising: a body adapted to fit into a nostril or ear canal of the subject and a hollow tubular member with a collar disposed inside the body. The plug is adapted to receive a tip of a syringe for injection of a fluid therapeutic agent through the hollow tubular member for nasal administration or administration to the ear. A kit comprising the plug and a syringe, as well as a method for administering a fluid therapeutic agent to a subject using the plug are also disclosed.

Nasal plug for treatment of nosebleed in a subject, comprising: a body adapted to fit into a nostril of the subject, the body comprising a first end arranged to face inward and a second end arranged to face outward during use; a hollow tubular member disposed inside the body and comprising a first opening facing inwardly and a second opening facing outwardly during use; wherein the tubular member further comprises a collar, adapted to prevent blood of a subject from escaping the body of the nasal plug, and wherein the collar is disposed completely inside the body.

Disclosed is a deformable analgesic nose plug, comprising a deformable core material and an outer coating provided on said deformable core material, wherein said outer coating comprises one or more analgesic compounds. The nose plug has a tapered distal end for insertion into a nostril and a proximal end whereby the nose plug is inserted into the nostril. The deformable core material may comprise a multi-phasic core material wherein a first phase of the multi-phasic core material is a solid or a semi-solid structure at a temperature of 35 C. or less and a second phase of the multi-phasic core material is characterized by liquefaction at a temperature of 37 C. or greater. The deformable core material may also comprise a porous resiliently compressible substrate. The deformable porous resiliently compressible core material may be one of polymeric sponges, naturally occurring sponges, fluffy cellulosic materials, cotton, rolled gauze, and mixtures thereof.

Sinusitis, enlarged nasal turbinates, tumors, infections, hearing disorders, allergic conditions, facial fractures and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies, endoscopic studies and transillumination studies. Access and occluder devices may be used to establish fluid tight seals in the anterior or posterior nasal cavities/nasopharynx and to facilitate insertion of working devices (e.g., scopes, guidewires, catheters, tissue cutting or remodeling devices, electrosurgical devices, energy emitting devices, devices for injecting diagnostic or therapeutic agents, devices for implanting devices such as stents, substance eluting devices, substance delivery implants, etc.