Disclosed herein are nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a HBV and/or HDV and/or HIV infection with one or more nucleotide analogs.

According to one embodiment, an absorbent article includes a moisture-impervious outer layer, an inner layer substantially co-extensive with the outer layer, and an absorbent layer interposed between the outer layer and the inner layer. The inner layer is treated with at least one antimicrobial booster. The absorbent layer is treated with at least one antimicrobial agent.

An absorbent article, containing a topsheet, a backsheet, and an absorbent body interposed between the topsheet and the backsheet, in which the topsheet has an arrangement portion of a liquid film cleavage agent in a thickness intermediate position.

Ultrathin absorbent hygienic pads comprising a top layer, a middle absorbent layer, and a bottom layer and comprising one or more channels anchored from the top layer through the middle absorbent layer and into the bottom layer are provided. The ultrathin absorbent hygienic pads provided can be used to absorb bodily fluids.

The present disclosure relates to methods and apparatuses for stretching, transferring, and bonding elastic parts under tension to an advancing carrier substrate during the assembly of absorbent articles. A continuous carrier substrate may be advanced in a machine direction at a first speed, and a discrete elastic part may be cut from a continuous elastic substrate having a direction of stretch in a cross direction. The speed of the discrete elastic part is changed from a second speed to the first speed, and the central region of the discrete elastic part is stretched in the cross direction. The discrete elastic part is bonded with the continuous carrier substrate such that the stretched central region extends in the cross direction between the first and second longitudinal edges of the continuous carrier substrate. The discrete elastic part may also be bonded with the carrier substrate with adhesive and/or mechanical bonds.

The present disclosure relates to absorbent articles having a waist gasketing element, with the gasketing element having an adhesive zone and one or more adhesive-free zones. At least a portion of the waist gasketing element is adhesively attached to a chassis of the absorbent article. Additionally, a portion of the waist gasketing element is mechanically attached to a portion of the absorbent article.

The present disclosure relates to absorbent articles having a waist gasketing element, with the gasketing element having an adhesive zone and one or more adhesive-free zones. At least a portion of the waist gasketing element is adhesively attached to a chassis of the absorbent article. Additionally, a portion of the waist gasketing element is mechanically attached to a portion of the absorbent article. The bio-based content of the absorbent article is from about 5% to about 100% using ASTM D6866-10, method B.

Biodegradable facial pads for exfoliation purposes are disclosed. The facial pad includes a top layer and a bottom layer made of a hydro-entangled, non-woven fibrous material. A coarse fabric material that may have undulations to provide exfoliating effect is sandwiched between the top layer and the bottom layer. The coarse fabric layer is configured to provide stiffness to the pads so as to aid and facilitate exfoliation. The top layer, bottom layer and the coarse material layer are pinched together along the edges to form an exfoliating pad of specified weight. The top layer is configured to overlay the coarse fabric layer to incorporate the undulations in the coarse fabric layer. This may form exfoliating peaks and absorbent cotton valleys that are suitable for removal of dead cells from the skin when used for exfoliating purposes.

An absorbent article including an absorbent core sandwiched between a liquid-permeable topsheet and a liquid-impermeable backsheet, wherein the absorbent core includes an absorbent component enclosed by a core cover including an upper side and a lower side, and a sealing arrangement for joining the upper and lower sides and including two channel sealings in the crotch portion defining a first channel sealing width and a second channel sealing width. The channel sealings are formed by thermo and/or mechanical welding pattern including a plurality of welding spots being arranged in the form of a first row along the longitudinal axis in which each welding spot extends along a first axis, and a second row along the longitudinal axis in which each welding spot extends along a second axis, the first axis and second axis defining a first angle in relation to each other.

The present invention relates to single-use hygiene care product, in particular an absorbent pad, consisting of a liquid absorbent layer in contact with human body and a back layer opposite to the liquid absorbent layer, the back layer being a breathable back sheet; a super absorbent layer arranged between the liquid absorbent layer and the back layer, a lotion layer arranged between the liquid absorbent layer and the super absorbent layer, the lotion layer containing skin-moisturizing lotion. The absorbent pad of the present invention can prevent patients from growing pressure sore due to the peel-off of their dry skin, hence preventing the development of pressure sore and perennial dermatitis. The use of breathable water-proof back layer can ensure air flow and at the same time prevent liquid leakage. The absorbent package is convenient and can effectively protect patients from erythra and perennial dermatitis.