A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of the biodegradable metal scaffold, wherein the biodegradable polymer coating has a degradation rate that is faster than the degradation rate of the biodegradable metal scaffold.

The invention relates to biomimetic, biodegradable composites including a magnesium (Mg) alloy mesh and a polymer/extracellular matrix (ECM). These hybrid composites, more particularly, are useful for the fabrication of medical implant devices, e.g., scaffolds, and are effective for bone regeneration. The fabrication process includes creating the Mg alloy mesh, and concurrently electrospinning the polymer and electrospraying the ECM onto the mesh.

An intervertebral implant for insertion into an intervertebral disc space between adjacent vertebral bodies or between two bone portions. The implant includes a spacer portion, a plate portion operatively coupled to the spacer portion and one or more blades for securing the implant to the adjacent vertebral bodies. The blades preferably include superior and inferior cylindrical pins for engaging the adjacent vertebral bodies. The implant may be configured to be inserted via a direct lateral trans-psoas approach. Alternatively, the implant may be configured for insertion via an anterior approach.

To provide a stent excellent in deformability, capable of maintaining a radial force for a longer period of time, and having bioabsorbability and a method of producing the same. The bioabsorbable stent has a core structure including a magnesium alloy and a corrosion resistant layer on the core structure, wherein the core structure is formed from a magnesium alloy containing 90 mass % or more of Mg as a main component, Zn, Zr, and Mn as accessory components, and 30 ppm or less of unavoidable impurities selected from the group consisting of Fe, Ni, Co, and Cu, and the alloy excluding aluminum and at least one sort of rare earths selected from the group consisting of Sc, Y, Dy, Sm, Ce, Gd, and La; and the corrosion resistant layer containing magnesium fluoride as a main component with a hydrophilic smooth surface is formed on the core structure with a smooth surface.

An intervertebral implant for insertion into an intervertebral disc space between adjacent vertebral bodies or between two bone portions. The implant includes a spacer portion, a plate portion operatively coupled to the spacer portion and one or more blades for securing the implant to the adjacent vertebral bodies. The blades preferably include superior and inferior cylindrical pins for engaging the adjacent vertebral bodies. The implant may be configured to be inserted via a direct lateral trans-psoas approach. Alternatively, the implant may be configured for insertion via an anterior approach.

A biodegradable metallic vascular stent includes: a base body which is tubular with a lumen along a longitudinal axis, wherein the base body has a plurality of circumferential support structures which are successively positioned along the longitudinal axis. The circumferential support structures are each composed of a sequence of repeat units and has two or more connectors, wherein two adjacent circumferential support structures are joined together by at least one of the connectors, and each of the connectors is attached to one of arched elements in the repeat units of the two adjacent circumferential support structures to be connected. The biodegradable metallic vascular stent possesses suited radial pressure, flexibility and fatigue strength. Furthermore, the stent is design for peripheral vascular disease and coronary artery disease treatment as well.

A pelvic implantation device that includes at least two outwardly directed, flat, fastening brackets arranged at an edge of a fastening ring, the fastening ring forming an opening; and a socket support body that includes a convex outer face configured to contact a pelvic bone; a distal edge that extends substantially orthogonally from a circumferential surface of the socket support body; and a tab, wherein the tab forms a portion of the circumferential surface of the socket support body, the tab including a proximal edge that extends substantially orthogonally from a surface of the tab, wherein the distal edge and the proximal edge are configured to contact an upper surface of the fastening ring.

A biodegradable in vivo supporting device is disclosed. In one embodiment, a coated stent device includes a biodegradable metal alloy scaffold made from a magnesium alloy, iron alloy, zinc alloy, or combination thereof, and the metal scaffold comprises a plurality of metal struts. The metal struts are at least partially covered with a biodegradable polymer coating. The biodegradable scaffold includes a radio-opaque marker made of a substance that blocks radiation. A cavity is manufactured in the scaffold and the radio-opaque marker is accommodated by the cavity.

The invention makes available a multi-part implant (10), comprising: a support element (20) for fixing the implant (10) to a bone material; wherein the support element (20) forms a receiving space; and a functional element (30) that can be introduced into the receiving space; wherein the functional element (30) can be fixed in the receiving space (26) by the support element (20) at least with respect to one degree of freedom.

The invention relates to magnesium reinforcements and magnesium-reinforced barrier membranes for use in biomedical applications, such as dental, craniofacial and orthopedic applications. The magnesium reinforcements and barrier membranes are composed of a biodegradable, magnesium/polymer composite. They can be used in a wide variety of applications, such as, but not limited to, vertical and horizontal ridge augmentation, guided bone/tissue regeneration, periodontal bone regeneration, fracture fixation and orthopedic and spinal bone grafting applications; as well as in general surgery (hernia repair) and urogynecological surgery.