Infusion pump deployment systems and related methods are described. In one embodiment, after actuation, a cannulation system may simultaneously deploy a cannula of a device into tissue and release the device from the cannulation system. Associated methods and constructions of the cannulation system and devices are also described.

A vial adapter configured to allow direct fluid withdrawal with a syringe from a fluid container having a self-healing sealing member is described. The syringe is connected to the vial adapter by a vial adapter connecting member and a corresponding syringe connecting member. In use, the fluid container is pressed against the vial adapter, and the vial adapter removably locks the fluid container to the vial adapter. When removably locked, a stake of the vial adapter pierces the sealing member.

A syringe assembly includes a barrel defining a chamber therein, pressurized sterile air in the chamber, a plunger including a piston slidable in the chamber in a sealing relation to displace a fluid in the chamber, a seal configured to retain the pressurized sterile fluid in the chamber between the piston of the plunger and the seal when the plunger is stationary, and a needle assembly extending distally from the barrel and in fluid communication with the chamber of the barrel.

Systems and methods for destroying or inhibiting cancer cells and other rapidly-dividing cells include coupling an alternating polarity (AP) magnetic field generator to a target body area and applying an AP magnetic field having a frequency of 0.5-500 kHz and a field strength of 0.5-5 mT to the target body area to achieve a desired inhibiting effect on cancer cells or other rapidly-dividing cells. Treatments provided by the system may be co-administered with an anti-cancer drug such as a chemotherapy drug, a hormone therapy drug, targeted therapy drugs, immunotherapy drugs, or an angiogenesis inhibitor drug.

A primary packaging for storage and/or administration of medical or pharmaceutical compounds includes a container that has a predetermined filling volume for receiving a medical or pharmaceutical compound. The container is permanently closed at a first end and has an integrally formed, circumferential flange portion at an open second end. The container has a cylindrical barrel that extends between the first end and the flange portion such that the barrel has an inner diameter and outer diameter corresponding to that of a standardized syringe for a nominal volume of the standardized syringe corresponding to the predetermined filling volume. Furthermore, a cross-sectional shape of the flange portion corresponds to the cross-sectional shape of a flange of a standardized vial. The primary packaging also includes a closure element that is adapted to fit tightly on the flange portion and into the barrel for sealing the open second end of the container.

IV spikes are described herein. An IV spike includes a spike body. The spike body can be formed of a first material and can include a spike portion converging to a point. The IV spike further includes at least one spike flow port formed through the spike body. The IV spike further includes a lower flow port in fluid communication with the at least one spike flow port. The IV spike can also include an overmolded engagement feature disposed around the spike body, wherein the overmolded engagement feature comprises a second material and is configured to retain the IV spike within an IV container.

A system includes a syringe adapter having a first end and a second end with the first end of the syringe adapter configured to be connected to a first container and the second end of the syringe adapter including a lock member having an open position and a closed position. The system also includes a vial adapter having a first end and a second end with the second end of the vial adapter configured to be connected to a second container and the first end of the vial adapter having a locking surface. The lock member includes at least one projection that extends radially outward. The syringe adapter has at least one corresponding projection configured to engage the at least one projection of the lock member to retain the lock member to the syringe adapter.

An apparatus that includes a container portion and a coupler portion. The container and coupler are, in one embodiment, mated via an adapter that includes a one-way valve. The coupler includes a second one-way valve. In use, a fluid source, such as a vial, is connected to the coupler. An air source, such as a syringe is also connected to the coupler. Air from the syringe is introduced to the vial via the second one-way valve. The second one-way valve prevents fluid from the vial from being drawn into the syringe. Introduction of air from the syringe into the vial forces fluid from the vial into the container via the first one-way valve. The first one-way valve prevents the fluid from escaping the container.

A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member.

A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body, the plunger member. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is at least partially retractable into plunger interior. The needle proximal end feature includes an annular distally facing surface.