Liquid transfer devices with an integral telescopic vial adapter for use with an infusion liquid container and an initially non-punctured intact discrete injection vial. The integral telescopic vial adapter is configured for initial telescopic snap mounting on a discrete injection vial leaving its injection vial stopper non-punctured until a subsequent compaction for puncturing the injection vial stopper. The integral telescopic vial adapter includes a safety catch mechanism for precluding advertent compaction from a pre-compacted state to a compacted state. The integral telescopic vial adapter includes a clamping arrangement for irreversibly clamping same in its final compacted state.

A load cell assembly includes a load cell and a deflection portion. The load cell includes a fixed end and a free end. The free end is configured to receive a force in a first direction. The deflection portion includes a first component and a second component. The first component is coupled to the free end of the load cell. The first component defines a first cam surface. The second component is configured to support the vessel. The second component defines a second cam surface. The second cam surface is configured to engage the first cam surface. In an engaged state, the second cam surface is in continuous direct contact with the first cam surface. In a disengaged state, at least a portion of the second cam surface is disengaged from the first cam surface. The load cell assembly includes a central axis.

The mixing system includes an adaptor, an integrated injection device removably attached to the adaptor comprising a switching element, a first reservoir containing a fluidic first material, and a trigger. The adaptor includes a first attachment location configured to attach a vial. The vial contains a second material within a second reservoir, wherein the second material contains a medicament formulation. The adaptor also includes a first connection element, a flow channel providing fluid communication of the switching element and the first connection element, a sensing arrangement for detecting a pre-defined position of the vial at the first attachment location, and an interlock element which is configured to allow operation of the trigger in order to establish a fluid communication between the first connection element and the first reservoir only if the sensing arrangement detects the pre-defined position of the vial at the first attachment location.

A disposable fluid transfer and mixing device is disclosed and includes an injector support surface for receiving an injection device thereon. A lyophilized drug vial, a diluent vial and a syringe are also attached to the device. The device features fluid passageways and a manual valve that may be manipulated so that the syringe may be used to transfer diluent from the diluent vial to the lyophilized drug vial, for reconstitution of the drug. The valve may also be configured so that the reconstituted drug is transferred from the lyophilized drug vial to the injection device. An automated transfer and mixing device receives an injection device, a lyophilized drug vial and a diluent vial and transfers diluent from the diluent vial to the lyophilized drug vial and shakes or vibrates the lyophilized drug vial to reconstitute the drug. The device then transfers the reconstituted drug from the lyophilized drug vial to the injection device.

A carousel configured to house a plurality of pump cartridges for a compounder system is provided. The carousel may include a plurality of cartridge pockets each having an extended portion that covers a portion of a cartridge and a bottom surface Shaving an extension with a recess. The bottom surface recess of each cartridge pocket may be shaped and sized to receive a needle housing of a pump cartridge in the cartridge pocket. A recess may be provided in the extended portion of each pocket that receives a protrusion that extends from a top surface of a backpack coupled to the pump cartridge to secure the pump cartridge in the cartridge pocket. The bottom surface recess may have an additional bottom surface that prevents actuation of the needle housing of the pump cartridge.

Prefilled syringes containing a succinylcholine chloride composition, where the prefilled syringes comprise a syringe barrel and a syringe tip comprising cyclic olefin monopolymer (“COP”) or cyclic olefin copolymer (“COC”). The syringes can also comprise a luer adapter integral with the syringe tip, where the syringe barrel, syringe tip and luer adapter are a single element comprising COP or COC. The succinylcholine chloride compositions include succinylcholine chloride, a tonicity agent and one or more pH adjusters in an aqueous solution having a pH from about 3.0-4.5. The prefilled syringes containing the succinylcholine compositions are storage-stable for extended periods of time at a temperature of 2-8° C., have acceptable physical parameters such as glide force and break force, and make safe and robust connections with needles and needleless luer adapter devices (“NLADs”).

The present disclosure provides aseptic vial piercing and sterilization systems, and methods of assembling, using and sterilizing same. The systems and methods utilize a pre-sterilized primary container including a first end, a first cavity, a second end with an opening in communication with the first cavity, a septum at least partially sealing the opening, and a product within the first cavity. The systems and methods include an injection assembly including a first end portion of a hollow flowpath forming member. The injection assembly and the primary container may be assembled in a non-sterile environment to form a second cavity extending about the first end portion of the flowpath forming member and to the primary container. The second cavity may then be selectively sterilized in a non-deleterious manner to the product to allow the first end portion to aseptically pierce the septum to extend into the first cavity.

Disclosed herein are methods, systems, and devices for collecting a fluid for use in connection with a fluid pumping device such as a breast pump. A fluid collection receptacle includes a rigid connector attached to the fluid collection receptacle. The rigid connector is connectable to a breast pump manifold. The fluid collection receptacle further includes a liquid tight seal in the fluid collection receptacle. The fluid collection receptacle may be constructed of a flexible plastic.

A syringe adapter includes a housing having a first end and a second end positioned opposite the first end, with the housing including a connector body positioned at the first end of the housing and configured to be secured to a syringe barrel, a cannula positioned within the housing, with the cannula defining a transfer opening and a valve opening, a seal arrangement positioned within the housing and movable within the housing, and an aspiration assembly comprising an aspiration housing defining an aspiration opening, a filter received by the aspiration housing, and one-way valve received by the aspiration housing, where the valve opening of the cannula is positioned within the aspiration housing, and where air is configured to flow into the filter via the aspiration opening, into the one-way valve, and into the valve opening of the cannula.

The connector includes a housing having a first casing and a second casing; a connection member formed into a cylinder an interior of which constitutes a first flow path L1 and arranged in the housing rotatably around an axis, a screw portion being formed on the connection portion in such a manner that the syringe can be screwed in; a flow path member arranged in the connection member; and a ratchet having a gear arranged in the connection member and having a plurality of teeth in the peripheral direction and a pawl arranged in the housing, and engaged in a protruding direction of the protrusion of the first casing from the first end surface with the restricting surface of the gear rotating in the direction of the syringe being screwed in so as to restrict the rotation of the gear.