A vial access device includes an outer housing defining an annular space and an inner space, an inner housing, and a connector configured to engage a mating connector with the connector having a body defining a central passageway and a flange that extends radially outward from the body. The flange and the housing defining a filter space that is in fluid communication with the annular space. A pressure equalization system is positioned within the annular space of the outer housing. The device also includes a vial connection element configured to be secured to a vial and having a body and a spike member extending from the body. The spike member defining a fluid passageway and a vent passageway with the fluid passageway in fluid communication with the central passageway of the connector and the vent passageway in fluid communication with the filter space and the annular space.

An example of a method of enabling medical fluid transfer between a source container and a destination container can comprise the steps of providing a closed-system fluid transfer module comprising a first closeable, resealable medical connector and a second closeable, resealable medical connector, a multidirectional fluid control valve with a driving interface configured to interface with an electromechanical driver of an electronic medical fluid transfer device, and an intermediate container or an intermediate pumping region; and instructing a user to couple the closed-system fluid transfer module to the electronic medical fluid transfer device.

Systems and method for improving fluid flow during medication delivery procedures, such as infusions or pooling, are provided. A spike is punctured though a seal in a container. A liquid substance is drained from said container through a pathway in the spike. The spike includes a channel which permit sliding movement of a snorkel for elevation above the liquid substance to permit air to enter the container from outside without foaming the liquid substance.

Various embodiments of the present invention are directed to transferring fluidic media from a vial to a reservoir. In various embodiments, fluidic media may be transferred from the vial to the reservoir by moving a housing portion to move a plunger head located in the reservoir to draw fluidic media from the vial to the reservoir. In other embodiments, fluidic media may be transferred from the vial to the reservoir while the reservoir is held by a holding unit and vibrated by a vibrator to remove air from the fluidic media. In some embodiments, fluidic media may be transferred from the vial to the reservoir by moving a handle operatively connected to a bias member for assisting with the transfer of fluidic media. In other embodiments, the transfer of fluidic media may be assisted by a bias member and a needle connecting atmosphere and the vial.

An adapter for accessing material in a container may include an adapter body with a bore through its longitudinal axis. The adapter may include one or more sealing surfaces and a threaded connection nested in the adapter body. The threaded connection may be configured to mate with an CORPAK ENFIT connection or a luer lock connection.

A combinatorial drug delivery device is provided for delivering a predetermined selection of drug components, each of the drug components being contained in a drug vial. The device includes a plurality of modules, wherein each of the modules includes: a body having an interior volume formed to accommodate a drug vial; a cannula protruding into the interior volume, the cannula terminating at a free end, first and second openings being formed in the free end with first and second lumens extending therefrom and through the cannula; a socket located on an exterior portion of the body; a first passageway extending between, and in communication with, the socket and the first lumen; a boss protruding from an exterior portion of the body; and, a second passageway extending from, and in communication with the second lumen, the second passageway extending through the boss to terminate at an exit opening formed therein.

In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.

Methods and devices are provided for filling one or more syringes with a liquid, essentially without air being trapped with the liquid in the one or more syringes. A temporary storage volumea buffer memberis used to temporarily hold the liquid and allow air to be removed from the liquid in the syringe. The size and/or shape of the temporary storage volumealso referred to as intermediate volumeallows the air to be removed more easily compared to the size and/or shape of a main volume of the one or more syringes.

A snorkel for improving fluid flow during medication delivery procedures is disclosed along with related delivery systems and methods. The snorkel includes a fluid passageway forming an interior passageway for ambient air. A fluid control device is located at the fluid passageway and is moveable between a closed position and an opened position to control passage of the ambient air at the interior passageway. The fluid passageway is sized and shaped to permit extension of a first end of the fluid passageway through a seal of a container and above a fluid line of a substance within the container while the container is oriented for infusion or pooling, the substance remains undrained, and a second end of the fluid passageway as well as the fluid control device remains outside of, and spaced apart from, the container.

The invention relates to a device (1) for reconstituting a pharmaceutical composition from at least a first component contained in a first container (2A) and a second component contained in a second container (2B), comprising: a fluidic unit (100) comprising: a first connector (101) coupled to the first container (2A), a second connector (102) coupled to the second container (2B), a pump (103), a fluidic circuit (104) connecting the first connector (101), the second connector (102) and the pump (103), wherein the first connector (101) comprises a crankpin (1011) in rotating engagement within a body (1010), said crankpin comprising a unique axial port (1011A) intended to fluidically couple to the first container, a radial port (1011B) fluidically connected to said axial port (1011A), and at least one channel (1011C) arranged therein so as to cooperate with the radial ports of the body (1010) to selectively connect the axial port (1011A) of the first connector with at least one channel portion of the fluidic circuit (104) depending on the angular position of the crankpin (1011) with respect to the body (1010), a power unit (200) releasably coupled to the fluidic unit (100), comprising: a power mechanism (203) for actuating the pump, transmission means connected between an actuator and the crankpin (1011) for rotating the first container (2A).