The invention provides topical formulations and methods comprising charged bioactive agents complexed with amphipol polymers for dermal and transdermal delivery, optionally further including TJ-modulating peptides.

A hair conditioner composition comprising arginine, a fatty acid having a C16 to C22 alkyl chain, and an aqueous carrier, all of which form a gel structure, and wherein the composition is free of a fatty alcohol.

The application relates to an emulsifying composition, in particular for cosmetic use, allowing an oil-in-water emulsion (O/W) to be obtained, the emulsion comprising at least one cyclodextrin and at least one O/W emulsifier of natural origin with a hydrophilic-lipophilic balance value (HLB) of more than 8. The O/W emulsifier of natural origin can be selected from alkyl polyglucosides, mixtures of at least one alkyl polyglucoside and at least one fatty alcohol, and non-ethoxylated polyol fatty esters. The application also relates to a composition of the Pickering emulsion type, in particular for cosmetic use, containing the emulsifying composition according to the invention, and to the process for preparing such a composition of the O/W Pickering emulsion type, in particular at low temperatures.

The present invention relates to a process for obtaining an encapsulated composition, to an encapsulated composition obtainable by this process, to products comprising these encapsulated compositions and to a use of these encapsulated compositions for obtaining a consumer product.

A method for preparing stable liquid emulsion forms of plant extract is provided. A plant extract having a bitter flavor is mixed with diluent oil as an oil mixture and heat is applied to the oil mixture. An emulsifying agent is dispersed in water as an emulsifying solution. The oil mixture is mixed with the emulsifying solution. The mixed oil mixture and emulsifying solution is homogenized as a liquid form of the plant extract. Gluconic acid is added to the liquid form of the plant extract. The bitter flavor of the plant extract is disguised by adding a bitter blocker to the liquid form of the plant extract.

Described herein, personal cleansing compositions, methods and uses. Personal cleansing compositions can include a surfactant, a perfume, a hydric solvent, and water, wherein the composition is structured.

The present invention provides a microemulsion mixture, comprising a microemulsion and an active ingredient, wherein the microemulsion comprises a water phase composite, comprising a water solution and a moisturizer; an oil phase composite; and a surfactant composite; and the active ingredient is the substrate of cytochrome P450 3A4 enzyme. The microemulsion of the present invention inhibits the expression of the cytochrome P450 3A4 enzyme so as to improve the efficacy of the active ingredient in the microemulsion mixture. The present invention further provides a method of using the microemulsion mixture, a pharmaceutical microemulsion mixture comprising the microemulsion mixture, and the method for treating psoriasis comprising administering the microemulsion mixture to a subject in need thereof.

A method for preparing stable liquid emulsion forms of plant extract is provided. A plant extract is mixed with a diluent oil as an oil mixture. Heat is applied to the oil mixture until the mixture reaches a threshold viscosity. An emulsifying agent is dispersed in water as an emulsifying solution. The oil mixture and emulsifying solution are mixed together. The mixed oil mixture and emulsifying solution are homogenized as a liquid form of the plant extract.

The purpose of the present invention is to provide: a cosmetic base material which is capable of stably retaining lecithin in the form of a liposome; and a cosmetic preparation which contains this base material and has excellent usability (such as soft texture when applied to the skin and quick adhesion to the skin) and excellent stability. The present invention relates to: a cosmetic base material which is characterized by containing (a) a liposome that contains (a-1) lecithin and (a-2) an oryzanol, and (b) an aqueous medium that contains (b-1) water and (b-2) a polyhydric alcohol, and which is also characterized in that the ratio of the blending amount of the liposome (a) to the blending amount of the aqueous medium (b), namely (a):(b) is within the range of from 1:99 to 1:32; and a cosmetic preparation which contains a microemulsion part and a liposome part that is composed of this base material.

A microemulsion composition containing: (A) an anionic surfactant; (B) an organopolysiloxane having at least two hydrosilyl groups in one molecule thereof shown in the following formula (I); (C) an organopolysiloxane having at least two olefinic unsaturated groups in one molecule thereof shown in the following formula (II); (D) a monohydric or polyhydric alcohol; and (E) water, where the microemulsion composition has a transparent or translucent appearance at 25° C. This provides a microemulsion composition having a transparent or translucent appearance when an organopolysiloxane having reactive functional groups such as hydrosilyl groups and olefinic unsaturated groups is used for an oil phase.

##STR00001##