A composition for detecting blood includes 3,3′, 5, 5′-tetramethylbenzidine, cumene hydroperoxide, and a surfactant. The composition is an aqueous solution. The surfactant is an anionic surfactant or a non-ionic surfactant. The composition is useful for the detection of blood, in particular occult blood in saliva. Also described are methods for detecting blood using the composition, a kit including the composition, and the use of a surfactant to reduce the time taken to detect blood.

A method for treating or preventing one of a fungal infection of a nail and a condition of a skin surface excluding an oral cavity. The method includes the step of applying a composition to one of a nail surface adjacent to the infection of the nail and the skin surface having the condition. The composition comprises a plant-based bioactive and between about 0.2% to about 3.0% by weight of a metal chlorite salt. The composition does not contain a therapeutically effective amount of chlorine dioxide.

A method for treating or preventing one of a fungal infection of a nail and a condition of a skin surface excluding an oral cavity. The method includes the step of applying a composition to one of a nail surface adjacent to the infection of the nail and the skin surface having the condition. The composition comprises a plant-based bioactive and between about 0.2% to about 3.0% by weight of a metal chlorite salt. The composition does not contain a therapeutically effective amount of chlorine dioxide.

A chewable composition for teeth-whitening comprising a first region and a second region separated by a barrier layer; the first region comprising carbamide peroxide having water content of about 2% or less, a wetting agent (e.g., glycerin), an anhydrous chewing gum base having water content of about 1% or less, an anhydrous fruit acid, and one or more gum additives; and the second region comprising a chewable composition comprising a gum base, a source of bicarbonate ion, and one or more gum additives. A kit comprising separate chewable compositions corresponding to the first and second regions, and methods for whitening teeth using the chewable composition are also provided.

A dental bleaching composition comprises a dental bleaching agent and a polyvinylpyrrolidone thickening agent. The bleaching composition may include a liquid component, flavoring agents, a basic substance and desensitizing agents, as desired. Polyvinylpyrrolidone avoids acid etching and chelation of teeth that were problematic in bleaches using carbomer as a thickener. A delivery system for delivering the bleaching composition comprises the aforementioned dental bleaching composition in combination with a moisture-resistant barrier layer such as a dental tray or a flexible strip of material.

A regimen for the long-term therapeutic treatment of rosacea. The regimen includes topically applying a pharmaceutical composition to the skin of a subject. The pharmaceutical composition includes about 1% w/w to about 10% w/w benzoyl peroxide as an active ingredient, and a pharmaceutically acceptable carrier or excipient. The benzoyl peroxide is the only active ingredient in the pharmaceutical composition, and the pharmaceutical composition is applied once daily for a period of about 52 weeks, to achieve, in a group of such subjects, a success rate of about 75%.

The present invention provides a tooth whitening film. The tooth whitening film comprises a dental bleaching agent comprising one or both of a non-hydrogen peroxide bleaching agent and hydrogen peroxide in a hydrogen peroxide-polymer complex, one or more polyphosphates, said one or more polyphosphates comprising one or more cyclic polyphosphates, one or more water soluble film-forming polymers, one or more plasticizers and one or more emulsifiers, wherein the film has a thickness from about 50 μm to about 500 μm. A kit comprising one or more such films having a thickness from about 50 μm to about 150 μm and a dental aligner is also provided. A process for the manufacture of the film is also provided, together with a method of using such a film to bleach teeth.

An aqueous cleansing composition for dental prosthetics and orthodontic devices, containing hydrogen peroxide, one or more carboxylic acids and one or more peracids, and methods for removing microorganisms and stains from dental prosthetics and other orthodontic devices using the cleansing compositions.

An aqueous cleansing composition for dental prosthetics and orthodontic devices, containing hydrogen peroxide, one or more carboxylic acids and one or more peracids, and methods for removing microorganisms and stains from dental prosthetics and other orthodontic devices using the cleansing compositions.

A chewable composition for teeth-whitening comprising a first region and a second region separated by a barrier layer; the first region comprising carbamide peroxide having water content of about 2% or less, a wetting agent (e.g., glycerin), an anhydrous chewing gum base having water content of about 1% or less, an anhydrous fruit acid, and one or more gum additives; and the second region comprising a chewable composition comprising a gum base, a source of bicarbonate ion, and one or more gum additives. A kit comprising separate chewable compositions corresponding to the first and second regions, and methods for whitening teeth using the chewable composition are also provided.