The present invention is directed to a hair care composition having an effective amount of a 2-pyridinol-N-oxide material and an effective amount of an iron chelator; wherein the combination of the iron chelator and the 2-pyridinol-N-oxide material provides high anti-fungal efficacy.

The present invention relates to an oral composition which contains a cationic bactericide and an anionic surfactant in combination and is capable of enhancing the adsorption of the cationic bactericide on the tooth surface and effectively securing the composition stability and solubility or dispersity in the oral cavity. The oral composition comprises the following components (A), (B), and (C): (A) an olefin sulfonic acid having 14 or more and 20 or less carbon atoms or a salt thereof, (B) a hydroxyalkanesulfonic acid having 14 or more and 20 or less carbon atoms or a salt thereof, and (C) a cationic bactericide, wherein the total content of the component (A) and the component (B) is 0.01 mass % or more and 4 mass % or less, and the content of the component (A) is 3 mass % or more and 50 mass % or less in the total content of the component (A) and the component (B).

The present invention is directed to a hair care composition having an effective amount of a 2-pyridinol-N-oxide material and an effective amount of an iron chelator; wherein the combination of the iron chelator and the 2-pyridinol-N-oxide material provides high anti-fungal efficacy.

The present invention relates to an oral composition which contains a cationic bactericide and an anionic surfactant in combination and is capable of enhancing the adsorption of the cationic bactericide on the tooth surface and effectively securing the composition stability and solubility or dispersity in the oral cavity. The oral composition comprises the following components (A), (B), and (C): (A) an olefin sulfonic acid having 14 or more and 20 or less carbon atoms or a salt thereof, (B) a hydroxyalkanesulfonic acid having 14 or more and 20 or less carbon atoms or a salt thereof, and (C) a cationic bactericide, wherein the total content of the component (A) and the component (B) is 0.01 mass % or more and 4 mass % or less, and the content of the component (A) is 3 mass % or more and 50 mass % or less in the total content of the component (A) and the component (B).

The present disclosure relates to an agent (A) for changing the colour of keratin fibres, in particular human hair, which agent comprises unilamellar vesicles (ULV) and/or multilamellar vesicles (MLV) in an aqueous medium, wherein the agent contains at least one C.sub.8-C.sub.30 fatty alcohol (a1), at least one ethoxylated fatty alcohol (a2), at least one anionic surfactant of the type of (optionally ethoxylated) fatty alcohol sulfates (a3), and one or more colour-changing salts (a4) from the group of sulfates, hydrogen sulfates, chlorides, and/or bromides in a total amount of from about 0.3 to about 6.0% by weight. The present disclosure further relates to a multi-component packaging unit, in which the aforementioned agent (A) is formulated separate from an oxidant preparation (B). The present disclosure further relates to a method for producing the agent (A).

The present invention relates to a process for dyeing keratin fibres, in particular human keratin fibres such as the hair, using one or more particular azinium dyes and one or more fluorescent dyes. The present invention also relates to a cosmetic composition comprising the dyes defined above, and also to a multi-compartment device containing said dyes. The present invention also relates to the use of said dyes for dyeing light keratin fibres, especially human keratin fibres such as the hair, in chestnut-brown, dark chestnut-brown, brown, brown with a glint, or even black, without using an additional dye other than those defined above.

The present invention relates to novel selective 11-beta-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors and the use thereof to prevent age-induced skin structure and function defects.

Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.

The present invention relates to effervescent compositions which are resistant to water vapor in the atmosphere and to methods of preparing such compositions. In particular, the invention relates to an effervescent composition comprising a co-crystal. The co-crystal comprises an acidic component and a basic component is separate. The co-crystal comprising the acidic component is resistant to water uptake avoiding initiating the effervescence prematurely. Upon dissolution of the co-crystal and the basic component effervescence occurs.

The present disclosure relates to an agent (A) for changing the colour of keratin fibres, in particular human hair, which agent comprises unilamellar vesicles (ULV) and/or multilamellar vesicles (MLV) in an aqueous medium, wherein the agent contains at least one C.sub.8-C.sub.30 fatty alcohol (a1), at least one ethoxylated fatty alcohol (a2), at least one anionic surfactant of the type of (optionally ethoxylated) fatty alcohol sulfates (a3), and one or more colour-changing salts (a4) from the group of sulfates, hydrogen sulfates, chlorides, and/or bromides in a total amount of from about 0.3 to about 6.0% by weight.

The present disclosure further relates to a multi-component packaging unit, in which the aforementioned agent (A) is formulated separate from an oxidant preparation (B). The present disclosure further relates to a method for producing the agent (A).