The present invention is related to a formulation of the prolactin receptor antibody mat3 and its use in the treatment of male and female pattern hair loss.

The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.

The present disclosure relates to compositions comprising collagen 7 and methods of using the same to treat DEB.

The present disclosure relates to a pump-type toothpaste composition capable of being provided as contained in a pumping type container, and to a pump-type toothpaste composition improving the spreading property to a tooth as the toothpaste composition discharged to a toothbrush penetrates into the toothbrush and having an effect of ultimately delivering a medicinal ingredient continuously for a long time in the oral cavity.

In addition, the present disclosure relates to a pump-type toothpaste composition with excellent commercial value, which can ensure discharge stability without hardening and accordingly, can be used in a pump-type container equipped with a dispenser pump (dip pump), which has a remarkable problem of hardening in the discharge port due to free movement of external air because of properties of the container, and thus can ensure even the convenient use.

A multifunctional dental composition may include polyoxyethylene sorbitan monooleate; sorbitan monooleate; benzoate sodium; distilled water; and ethylene diamine tetra acetic acid. For dental use, the required hydrophilic/lipophilic balance of the composition may be 7; and a critical micellar concentration of the composition may be 0.5%. The dental composition may be applied in a manner similar to how tap water is conventionally used, and the composition may be delivered to the dental unit system using various methods.

Hair coloring compositions that form a transparent microemulsion and have a desirable texture. The hair coloring compositions may include about 0.1 to about 10 wt. % of one or more oxidative dye precursors; about 0.1 to about 15 wt. % of one or more anionic surfactants chosen from acyl amino acid surfactants; about 0.1 to about 15 wt. % of one or more amphoteric surfactants; about 0.1 to about 30 wt. % of a plurality of nonionic surfactants; and water. The plurality of nonionic surfactants include about 0.1 to about 15 wt. % of one or more alkyl polyglucosides; about 0.1 to about 15 wt. % of a sorbitan compound, a derivative thereof, or a mixture thereof; and about 0.1 to about 10 wt. % of one or more polyol esters.

A composition (d) includes (per 100% of its weight): a) 90 wt.-% to 99.0 wt.-% water including, in dissolved form, 0.002 mol/L to 0.1 mol/L of at least one salt of ammonium cation or of a monovalent or multivalent metal cation with an organic or inorganic anion; b) 0.5 wt.-% to 5 wt.-% of at least one crosslinked anionic polyelectrolyte; and c) 0.5 wt.-% to 5 wt.-% of at least one compound having formula (II), where the weight ratio of the crosslinked anionic polyelectrolyte to the compound of formula (II) is greater than or equal to 0.2 and less than or equal to 2.0, and the molar ratio of the compound of formula (II) to the salt is greater than or equal to 0.05 and less than or equal to 1. Also disclosed is the composition in cosmetics and to a method for lightening the thickened salt-rich composition.

The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.

An oral care composition with an aqueous phase, hydrophobic phase, active agent, and emulsifier. A high internal phase emulsion with aqueous phase, hydrophobic phase, active agent, and emulsifier. An oral care composition with aqueous phase, hydrophobic phase, active agent, and emulsifier. Methods of using disclosed compositions for active agent delivery.

A multi-phase oral composition with aqueous phase, hydrophobic phase, active agent, and optionally emulsifier, which is rinseable from a surface and/or has a high water dispersibility. A jammed oil-in-water composition with aqueous phase, hydrophobic phase, active agent, and optionally emulsifier, which is rinseable from a surface and/or has a high water dispersibility. Methods of using disclosed compositions for active agent delivery.