The present invention describes stable topical barrier compositions comprising primary polyamines and uses thereof for protecting the skin from external stressors, for improving skin's moisture and fort stimulating healing of the skin. These compositions may be used in a variety of cosmetic and therapeutic applications including for promoting wound healing, for reducing or preventing the formation of hypertrophic scar tissue, for reducing or preventing skin irritation and inflammation, for increasing skin's moisture and/or for reducing or preventing skin's signs of aging.

An effervescent foot bath which employs an acid in combination with a carbonated base to produces a effervescing effect in a closed foot tub. The reaction has been designed to function externally to soften and begin the process of removing dry, rough peeling skin from the feet.

The present invention relates to a particulate nano-lipid carrier for the encapsulation of a bioactive material, and a method for producing same, and more specifically, to a particulate nano-lipid carrier having excellent nanoparticle stability and improved encapsulation of water-soluble drugs. A nano-lipid carrier according to the present invention has significantly improved bioactive material stability and encapsulation efficiency compared to conventional carriers, and it is anticipated that the nano-lipid carrier according to the present invention will be immediately commercializable as a raw material for cosmetics by means of a hair follicle targeting production method suitable for mass production.

A formulation for transdermal delivery of one or more ketone components through the skin of a subject, comprising: a ketone component in an amount between about 10-60% w/w; a penetrant portion in an amount less than about 60% w/w, and water in an amount less than about 50% w/w.

A composition for ameliorating skin condition having a collagen production promoting effect, a composition for ameliorating skin resilience, a composition for ameliorating skin wrinkles, a composition for ameliorating skin sagging, and a composition for promoting collagen production.

The present invention provides a topical composition for a nanobubble cosmetic with which functional properties required by various types of cosmetic products can be improved. The present invention is a topical composition for a nanobubble cosmetic to be used in a container equipped with a device mechanism for generating nanobubbles, said topical composition containing a polyoxypropylene diglyceryl ether and ethoxydiglycol, or containing hyaluronic acid or a salt thereof, or containing ethanol and menthol or a derivative thereof, or containing sorbitol and glycerin, or containing phytosteryl/octyldodecyl lauroyl glutamate, or containing glycereth-26, or containing hydrogenated lecithin and polysorbate 20, or containing ethanol and polysorbate 20.

A method is provided for diminishing wrinkles, fine lines, blemishes, skin discoloration, cellulite, and/or bruising in human skin including administering a topical treatment on a patient's skin. The topical treatment includes Hyaluronic Acid; a suspension mixture; Tetrahydropiperine, Horse Chestnut Extract, Lecithin; and an effective dose of at least 0.5% of a compound indole-3-carbinol or its derivatives. The topical treatment is applied to the patient's skin in need of diminishment in wrinkles, fine lines, blemishes, skin discoloration, cellulite, and/or bruising.

Compositions and methods for stimulating intrinsic hyaluronic acid production are provided herein. Compositions and methods for stimulating intrinsic hyaluronic acid production can improve skin moisture and elasticity.

The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.

A self-emulsifying bioactive concentrate produced by a process comprising the steps of (a) creating a lysophospholipid concentrate comprised of a de-oiled lecithin source and 0.1% to 10% of an enzyme with having phospholipase A activity, wherein the lysophospholipid concentrate contains greater than 20% lysophosphatidyl-choline; and (b) combining the lysophospholipid concentrate from step (a) with a retinyl ester formed by the reaction of retinol and one or a mixture of unsaturated fatty acid(s).