Compositions for topical treatment to reduce the appearance of the hyperpigmented lesions of melasma are presented. Such compositions include defensins in concentrations that are below those that exhibit antimicrobial activity, and can be in the form of a topically applied gel, lotion, wash, shampoo, cream, or mask. Various formulations for such compositions, which can include various pharmaceutically acceptable stabilizers, emollients, and fragrances, are provided.

The present invention relates to a disinfectant foam based on alcohol for disinfecting the skin. The disinfection foam according to the invention avoids the disturbance of the skin barrier that is usual with alcohol-based disinfectants and does not require silicone surfactants or polyfluorinated chemicals.

The present invention relates to the use of a composition with beneficial skin bacteria-friendly properties. The composition of the present invention does not inhibit the growth of beneficial skin bacteria, has beneficial skin bacteria-friendly properties, can maintain or promote the growth of beneficial bacteria without addition of active materials such as prebiotics or probiotics, and therefore can be provided as a microbiome cosmetic composition.

The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.

The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.

A environmentally and user-safe non-nano particle zinc oxide sunscreen composition that is homogenous at rest with semi-sheer to transparent application including 20 to 30% by weight of zinc oxide, 50 to 70% by weight of an oil mixture and 10 to 30% by weight of a water-resistant wax comprising beeswax, calendula wax, or a mixture thereof.

Provided is a method of preparing a bioactive substance-encapsulatedethosome, the method including: preparing an aqueous solution of a bioactive substance,preparing a lipid-dissolved solution by dissolving lipids in ethanol, preparing a hydrated liquid crystalline phase by hydrating the lipid-dissolved solution by mixing and agitating the bioactive substance aqueous solution together with the lipid-dissolved solution, and preparing an ethosome solution by adding purified water to the hydrated liquid crystalline phase to produce a mixture and agitating the mixture.

Compositions and methods for skincare treatment are provided. The invention relates more generally to skin care treatment and more particularly, to compositions and methods for promoting healthy skin, skin regeneration, skin repair, skin bed preparation, and enhanced wound healing.

Provided is a method of treating a penis of male human using a composition including a Maca root extract as an active ingredient to enhance erection of the penis. The method includes: applying an effective amount of the composition to a skin of a penis of a male human in need thereof. The composition comprises: a skin conditioner, a solvent, a humectant, a viscosity increasing agent, a surfactant, a preservative, a chelating agent, and perfume. The skin conditioner includes: a Maca root extract, a natural extract, niacinamide, glyceryl acrylate/acrylic acid copolymer, hyaluronic acid, arginine, hydrolyzed collagen, sucrose distearate, hydrogenated lecithin, and dimethicone. The composition includes: 0.5 to 10 parts by weight of the Maca root extract; and 1 to 5 parts by weight of the natural extract based on 100 parts by weight of the composition.

Provided is a cosmetic composition for blocking infrared rays and ultraviolet rays at the same time, the cosmetic composition including an inorganic material which blocks ultraviolet rays, an inorganic material which blocks infrared rays, and a dispersing agent.