A topical mosquito repellent and sunscreen product includes active and inert ingredients. The active ingredients include natural materials and may include soybean oil, peppermint oil, cinnamon oil and citronella oil. The inert ingredients include natural materials and may include bee's wax, sunflower oil, isopropyl alcohol, zinc oxide, water, vanillin, lecithin, salt, triethyl citrate and turmeric oil.

Provided herein is technology relating to liposomes and particularly, but not exclusively, to compositions of liposomes encapsulating a biologically active agent, methods of preparing liposomes encapsulating a biologically active agent, and uses of liposomes encapsulating a biologically active agent to treat a subject.

The present invention relates to compositions forming a low viscosity mixture of: a) at least one diacyl glycerol; b) at least one phosphatidyl choline; c) at least one oxygen containing organic solvent; d) at least one GnRH analog; Wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The invention further relates to methods of treatment comprising administration of such compositions, pre-filled administration devices and kits containing the formulations.

A method for the permanent shaping and color modification of keratinic in a single process includes the following steps. First, an aqueous composition, including at least one keratin-reducing compound and at least one alkalizing agent, is applied to the keratinic fibers and is left on the keratinic fibers for a period of 5 to 50 minutes at a temperature of 20 to 45° C. The keratinic fibers are rinsed, and optionally dried. Next, a composition including at least one oxidation dye precursor and at least one oxidizing agent is applied to the keratinic fibers and the keratinic fibers are deformed. That composition is allowed to act for 10 to 35 minutes. An aqueous composition including at least one oxidizing agent, is applied to the keratinic fibers for 30 seconds to 15 minutes. The keratinic fibers are rinsed out, along with removal of the deformation aids.

Improved formulations for topical treatment that ensure at least localized transdermal or systemic delivery of an active agent through skin, nails or hair follicles are disclosed.

The present invention relates to a composition for stabilizing poorly soluble ingredients, comprising hydrogenated lecithin and an anionic surfactant as effective components. In addition, the present invention relates to a method for stabilizing poorly soluble ingredients in cosmetic formulations by using said composition for stabilizing poorly soluble ingredients, a cosmetic composition comprising said composition for stabilizing poorly soluble ingredients and a poorly soluble component, and a preparation method of said cosmetic composition. The composition for stabilizing poorly soluble ingredients of the present invention stabilizes the poorly soluble ingredients in cosmetic formulations, thereby preventing same from being separated or precipitated. Accordingly, by overcoming the limitations of poorly soluble ingredients that tend to precipitate over time and thus were difficult to apply to cosmetic compositions, the present invention provides a cosmetic composition containing such poorly soluble ingredients and having various types of formulations.

The application relates to a lipid conjugate of formula M-X1-L wherein M is a molecule of interest such as a drug moiety; X1 is a linker group such as ester, ether or carbamate; and L is a lipid scaffold represented by formula (IId): -L1-[L2(H)(X2R)]n-L3-[L4(H)(X2R)]p-L5-L6 and wherein L comprises 5 to 40 carbon atoms and 0 to 2 carbon-carbon double bonds. The lipid conjugate can p be formulated in a drug delivery vehicle such as a lipid nanoparticle (LNP).

A skin crème with CBD variants. The skin crème is a formulation to relieve joint and muscle pain, pain from arthritis. The skin crème also works to repair skin and reduce wrinkles, as the CBD nourishes the skin and has been shown to be more effective in skin repair and wrinkles reduction. There are three embodiments that include different forms of CBD. The first embodiment is a skin crème with CBD oil. The second embodiment is a skin crème with water soluble CBD. The third embodiment is a skin crème with Nano CBD.

The present invention relates to a method for solubilizing poorly water-soluble organic cosmetic agents, to the solubilisate and cosmetic preparations produced by this method and respective uses of the solubilisate in cosmetic preparations. A phosphatidylcholine-based solubilization method is disclosed.

Disclosed herein is a pre-treatment and/or treatment formulation for transdermal delivery of a dermal pre-treatment agent and/or one or more dermal contouring agents through the skin of a subject, wherein the pre-treatment formulation comprises: a) a buffering agent comprising at least one carbonate salt, lysine, tris, a phosphate buffer and/or 2-imidazole-1-yl-3-ethoxycarbonylpropionic acid (IEPA), or a combination thereof in an amount between about 0.05-60% w/w; and b) a pre-treatment penetrant portion in an amount between about 40 to 99.95% w/w, and wherein the treatment formulation comprises: a) one or more acylating agents in an amount between about 0.25-25% w/w; and b) a treatment penetrant portion in an amount between about 40 to 75% w/w and methods for transdermal delivery of the pretreatment and/or treatment formulation through the skin of a subject.