The present disclosure relates to thermoresponsive oil-in-water nanoemulsions that include: (a) one or more amphiphilic triblock copolymers; (b) one or more oils in the form of nanoemulsion droplets having an average size of about 20 nm to about 500 nm; (c) about 5 to about 40 wt. % of one or more surfactants; (d) one or more nonionic co¬ surfactants; and (e) water, wherein the nonemulsion undergoes a sol-to-gel transition at about 20° C. to about 50° C. One or more lipophilic active ingredients and/or one or more hydrophilic active ingredients may be incorporated into the nanoemulsions. The nanoemulsions are particularly useful for medical, pharmaceutical, and cosmetic applications.

Various embodiments according to the present disclosure provide a coating composition. The coating composition includes a carrier. The coating composition further includes a substantially non-odorous fragrance modulator present in the amount of from about 0.1 wt % to about 50 wt %, relative to the total weight of the composition.

A transdermally absorbable base material including: a lipid peptide compound including at least one of compound of Formula (1) below and the similar compounds or pharmaceutically usable salts thereof; a surfactant; a specific polyhydric alcohol; a fatty acid; and water, ##STR00001##
wherein R.sup.1 is a C.sub.9-23 aliphatic group; R.sup.2 is a hydrogen atom or a C.sub.1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; R.sup.3 is a —(CH.sub.2).sub.n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH.sub.2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms, or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.

A fragrance composition having improved intensity and/or longevity of the fragrance profile, including less than about 30 wt % of low volatile fragrance materials (i.e., base notes) having a vapor pressure less than 0.001 Torr at 25° C., and at least one non-odorous fragrance modulator form from an alkoxylated glucoside.

The present invention relates to compounds of general formula (I): ##STR00001##
wherein Y, R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification. The invention also relates to cosmetic or dermocosmetic composition containing such compounds. The compounds according to the invention are useful as photoprotective agents.

Provided herein is an aqueous mouthwash formulation comprising a salt of an Nα-acyl-L-arginine alkyl ester and a peroxide source. The mouthwash formulation provides anti-microbial activity and whitening activity.

A transdermally absorbable base material including: a lipid peptide compound including at least one of compound of Formula (1) below and the similar compounds or pharmaceutically usable salts thereof; a surfactant; a specific polyhydric alcohol; a fatty acid; and water,

##STR00001##

wherein R.sup.1 is a C.sub.9-23 aliphatic group; R.sup.2 is a hydrogen atom or a C.sub.1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; R.sup.3 is a —(CH.sub.2).sub.n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH.sub.2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms, or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.

Biodegradable surfactants are described, in which an amphiphilic heteroatom containing hydrocarbon optionally comprising at least one counterion (Z), and related compositions, methods and systems. Biodegradable surfactant described herein has an aHLB value in accordance with equation (1): aHLB=20*Gh/(Gh−Gt) (1) wherein Gh is the Group Number of a hydrophilic head portion of the biodegradable surfactant optionally comprising the at least one counterion (Z), and Gt is the Group Number of a hydrophobic tail portion of the biodegradable surfactant. A biodegradable surfactant in the sense of the disclosure can be tuned to a set hydrophilic-lipophilic balance (aHLB) by selectively modifying at least one tuning moiety of the biodegradable surfactants to provide tuned biodegradable surfactants having an increase or decrease in their adjusted hydrophilic-lipophilic balance (aHLB).

An external preparation containing the following component (A) and component (B). Component (A): ionic polymer particles containing structural units derived from (a) one or more hydrophobic monomers selected from the group consisting of styrene and a derivative thereof, a vinyl ester, and a hydrophobic acrylic monomer, and (b) an ionic hydrophilic monomer or a salt thereof, wherein the ratio by mass of (a) to (b), (a)/(b) is 99.5/0.5 to 80/20, and the ionic polymer particles have a glass transition temperature of higher than 5° C. and 120° C. or lower. Component (B): one or more compounds selected from the group consisting of a phenoxyethanol (B1), a 2-ethylhexyl paramethoxycinnamate (B2), a benzyl alcohol (B3), a sorbitol (B4), a specific oxyalkylene derivative (B5), a polyoxyalkylene alkyl glucoside (BG), an oleic acid (B7), an alkyl benzoate (B8), a xylitol (B9), a 2-ethylhexyl (RS)-2-cyano-3,3-diphenylprop-2-enoate (B10), and a methylphenylpolysiloxane (B11).

A composition comprising: from 0.2 wt-% to 3 wt-% total of arginine, glycine, or a combination thereof based on the total weight of the composition; and from 0.3 wt-% to 3 wt-% total of one or more surfactants, based on the total weight of the composition, of Formula I: HOCH.sub.2—(CHOH).sub.n—CH.sub.2NR.sup.1R.sup.2 (I) wherein R.sup.1 and R.sup.2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R.sup.3, and SO2R.sup.4; with R.sup.3 and R.sup.4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5.