The present disclosure provides a method of treating cellulite in a subject in need thereof by administering a composition that comprises a protein having hyaluronidase activity to a region of skin having cellulite on the subject. Also provided are methods of reducing the appearance of cellulite in a subject in need thereof comprising administering a composition that comprises a protein having hyaluronidase activity to a region of skin having cellulite on the subject, wherein the administration results in a reduction in a grade of severity of the cellulite.

Aspects of the invention include a method of treating hair of a subject with an artificial melanin material comprises contacting in a solution artificial melanin precursors with an oxidizing agent at a temperature greater than or equal to 30° C. in the presence of the hair of the subject to form the artificial melanin material; wherein the artificial melanin material associates with the hair of the subject, thereby treating the hair of the subject. Optionally, the contacting step results in deposition of the artificial melanin material on the hair of the subject and/or uptake of the artificial melanin material into the hair of the subject.

Aspects of the invention include a method of treating hair of a subject with an artificial melanin material comprises contacting in a solution artificial melanin precursors with an oxidizing agent at a temperature greater than or equal to 30° C. in the presence of the hair of the subject to form the artificial melanin material; wherein the artificial melanin material associates with the hair of the subject, thereby treating the hair of the subject. Optionally, the contacting step results in deposition of the artificial melanin material on the hair of the subject and/or uptake of the artificial melanin material into the hair of the subject.

A single or multi-ply flushable and dispersible wet wipe including a wet laid fibrous web imprinted using a structuring fabric, a binder composition comprising poly(vinyl) alcohol, poly(vinyl) acetate, poly (ethylene) (vinyl) alcohols, poly (ethylene) (vinyl) acetate, copolymers of vinyl acetate-ethylene, or combinations thereof, and one or more additives. In an exemplary embodiment, the fibrous web is wetted by a wetting solution comprising 0.1% to about 10% by weight of one of the following: (1) boric acid; and (2) boric acid and a mono or divalent salt.

A single or multi-ply flushable and dispersible wet wipe including a wet laid fibrous web imprinted using a structuring fabric, a binder composition comprising poly(vinyl) alcohol, poly(vinyl) acetate, poly (ethylene) (vinyl) alcohols, poly (ethylene) (vinyl) acetate, copolymers of vinyl acetate-ethylene, or combinations thereof, and one or more additives. In an exemplary embodiment, the fibrous web is wetted by a wetting solution comprising 0.1% to about 10% by weight of one of the following: (1) boric acid; and (2) boric acid and a mono or divalent salt.

Improved dermal filler formulation comprising a hyaluronic acid and a botulinum toxin.

Improved dermal filler formulation comprising a hyaluronic acid and a botulinum toxin.

The invention relates to the use of an animal-protein-free botulinum toxin composition to treat a disease, disorder or condition in a patient in need thereof whereby the animal-protein-free botulinum toxin composition exhibits a longer lasting effect in the patient compared to an animal-protein-containing botulinum toxin composition.

The invention relates to the use of an animal-protein-free botulinum toxin composition to treat a disease, disorder or condition in a patient in need thereof whereby the animal-protein-free botulinum toxin composition exhibits a longer lasting effect in the patient compared to an animal-protein-containing botulinum toxin composition.

Compositions contain boron nitride nanomaterials at least partially coated with biomolecules.