Automated devices for detecting and removing dental biofilms are described herein. In some embodiments, the disclosed subject matter includes a device for administering a suspension comprising iron oxide nanoparticles to teeth to chemically treat and mechanically remove dental biofilms. In some embodiments, disclosed subject matter includes a device for administering a suspension comprising iron oxide nanoparticles and hydrogen peroxide to teeth to kill bacteria within a biofilm matrix and degrade the biofilm matrix and assembling the iron oxide nanoparticles into autonomous magnetic bristles or antimicrobial robots to mechanically remove biofilm. Devices and methods for real-time detection of dental plaque and monitoring of removal of dental plaque are also disclosed herein.

The present disclosure is directed to a composition for managing exaggerated sebum production in oily-prone skin, the composition containing: (1) a mixture of at least: (a) from about 0.02 to about 1% by weight of an ingredient capable of activating cannabinoid type-2 receptors (“CB.sub.2”); (b) from about 0.1 to about 3% by weight of a blend of Tetraselmis chuii and Fucus spiralis algae extracts; (c) from about 0.1 to about 4% by weight of an extract of Centella asiatica; and (d) from about 0.01 to about 0.05% by weight of an extract of Tulsi, wherein all weights are based on total weight of the composition; (2) optionally, an emulsifier; and (3) a dermatologically acceptable carrier, wherein the composition has a pH ranging from about 4.5 to about 5.5.

The present disclosure is directed to a composition for managing exaggerated sebum production in oily-prone skin, the composition containing: (1) a mixture of at least: (a) from about 0.02 to about 1% by weight of an ingredient capable of activating cannabinoid type-2 receptors (“CB.sub.2”); (b) from about 0.1 to about 3% by weight of a blend of Tetraselmis chuii and Fucus spiralis algae extracts; (c) from about 0.1 to about 4% by weight of an extract of Centella asiatica; and (d) from about 0.01 to about 0.05% by weight of an extract of Tulsi, wherein all weights are based on total weight of the composition; (2) optionally, an emulsifier; and (3) a dermatologically acceptable carrier, wherein the composition has a pH ranging from about 4.5 to about 5.5.

Systems, devices, non-transitory computer storage mediums, and methods are described herein for pharmaceutical benefits management including routing pharmaceutical claims over a computer network. The system includes a computer network and a client device communicatively coupled to the computer network. The client device is configured to receive order information representative of a prescription drug prescribed for a consumer. The system includes a communications switch configured to derive a processor control number associated with the order information and route the order information based on the processor control number. The system includes a pharmaceutical benefits manager configured to authorize the prescription drug with the reimbursement based on the processor control number and configured to transmit the authorization with the reimbursement to the client device.

Cleaning compositions having engineered fatty acid alpha-dioxygenases and methods of using said compositions to provide a benefit by converting long chain fatty acids present in soils into 2-hydroperoxy fatty acids or terminal aldehydes.

Cleaning compositions having engineered fatty acid alpha-dioxygenases and methods of using said compositions to provide a benefit by converting long chain fatty acids present in soils into 2-hydroperoxy fatty acids or terminal aldehydes.

The present invention relates to methods and compositions for the delivery of cosmetics and medicants. In some embodiments, the invention relates to compositions comprising both hydrophobic and hydrophilic polymers. In preferred embodiments, the invention relates to the delivery of peptides, small molecules and other bioactive compounds using the compositions and methods disclosed herein.

The present invention relates to methods and compositions for the delivery of cosmetics and medicants. In some embodiments, the invention relates to compositions comprising both hydrophobic and hydrophilic polymers. In preferred embodiments, the invention relates to the delivery of peptides, small molecules and other bioactive compounds using the compositions and methods disclosed herein.

An oral care kit comprising an oral care implement having a first reservoir containing a first oral care agent comprising a first whitening reagent that includes triacetin; and a container having a second reservoir containing a second oral care agent, the second oral care agent comprising a catalytic enzyme and a second whitening reagent that includes peroxide forming compound.

The invention relates to a method for obtaining the water-insoluble fraction of Carica papaya sap, enriched with Carica papaya lipase, the water-insoluble fraction obtainable by this method, a method for the preparation of an activated fat and/or an activated wax by means of said water-insoluble fraction of the Carica papaya sap, the activated fat and/or the activated wax capable of being obtained by this method, a composition combining said activated fat and/or said activated wax, as well as the cosmetic use of these products.