The present invention relates to the field of skin rejuvenation. Specifically, the present invention provides compositions and methods for promoting skin rejuvenation using a toll-like receptor 3 (TLR3) agonist and retinoic acid or derivatives thereof. In a specific embodiment, a method for treating wrinkles in a subject comprises the steps of (a) administering to the area of the subject comprising a wrinkle a composition comprising an effective amount of retinoic acid or a derivative thereof; and administering to the area of the subject comprising a wrinkle a composition comprising an effective amount of a TLR3 agonist.

Compositions and methods for treating administering retinoid or retinoid-related compounds without side effects.

A skin crème with CBD variants. The skin crème is a formulation to relieve joint and muscle pain, pain from arthritis. The skin crème also works to repair skin and reduce wrinkles, as the CBD nourishes the skin and has been shown to be more effective in skin repair and wrinkles reduction. There are three embodiments that include different forms of CBD. The first embodiment is a skin crème with CBD oil. The second embodiment is a skin crème with water soluble CBD. The third embodiment is a skin crème with Nano CBD.

A cosmetic composition, typically, including about 0.01 to about 3 wt. % of retinol; about 0.5 to about 10 wt. % of sodium polyacrylate; about 0.25 to about 10 wt. % of one or more nonionic emulsifier; about 3.5 to about 12 wt. % of a fatty phase, wherein the fatty phase comprises one or more fatty compound; and water, wherein all weight percentages are based on the total weight of the cosmetic composition. The cosmetic composition may be an oil-in-water emulsion.

A cosmetic composition including about 0.01 to about 3 wt. % of retinol; about 0.01 to about 1 wt. % of tetra-di-t-butyl hydroxyhydrocinnamate; about 0.01 to about 3 wt. % of trisodium ethylenediamine disuccinate; about 0.5 to about 7 wt. % of polyglyceryl-3 methylglucose distearate; about 0.9 to about 7 wt. % of sodium polyacrylate; about 0.5 to about 8 wt. % of an oil phase; and water, where all weight percentages are based on the total weight of the cosmetic composition. Additionally, the cosmetic composition is typically formulated to form an oil-in-water emulsion. Methods for treating damaged skin with cosmetic compositions are also disclosed herein.

The invention is Total Body Moisture. The Butter is used for conditioning the scalp and hair promoting hair growth and moisturizing for natural, permed, or relaxed hair as well as healing the skin all over the entire human body. It can be used for moisturizing after bath or shower, protecting skin from some UV rays, healing minor cuts, bums, and abrasions. It also can be used to soothe itching skin from the effects of eczema or psoriasis. TBM is also used to decrease wrinkles, fine lines, and minor acne on the skin surface. The main base oil of TBM is pure African Shea Butter in any shade and variation. Carrier oils such as Coconut oil, jojoba oil, black castor oil, argan oil, hemp seed oil, wheat germ oil, almond oil, avocado oil, and grapeseed oil are used to add to the clinical benefits of the pure African shea butter base.

Cosmetic compositions providing improved retinol penetration. The cosmetic compositions typically include about 0.01 to about 3 wt. % of retinol; about 0.1 to about 14 wt. % of sodium polyacrylate; about 0.2 to about 10 wt. % of one or more nonionic emulsifier; about 0.5 to about 12 wt. % of a fatty phase, wherein the fatty phase comprises one or more fatty compounds; and water, wherein the cosmetic composition is an oil-in-water emulsion, and all weight percentages are based on the total weight of the cosmetic composition. Methods for treating damaged skin with cosmetic compositions are also disclosed herein.

Described herein are dermatological compositions, formulations containing wild type or genetically modified Cutibacterium bacteria and methods for use thereof of skin. The cosmetic and therapeutic formulations described herein can be used as cosmetic daily skin treatments or for treating skin inflammation or disorders including acne, psoriasis, rosacea, dermatitis, or eczema.

The disclosure relates to porous and non-porous silica capsules (capsules in capsule or core-shell capsules), porous microspheres, as well as their direct phase emulsification process without surfactant and their use, wherein the particles comprise a liposoluble active/payload.

Disclosed are stable, non-irritating, retinoid containing formulations for topical application to the skin for modulated sheet-peeling of the skin without inflammatory response that retards healing of the skin. The topical formulations have concentration levels of ingredients, including retinol, a retinol activation system having a surfactant and a solvent, anti-inflammatory agents, that are formulated for exfoliating skin in skincare treatments such as chemexfoliation, peeling, dermal restructuring, without associated inflammatory affects, such as irritation, redness, drying, oozing, swelling, tenderness of skin, which retard healing of the skin. Also provided are methods for the formulation, manufacture and use of the disclosed formulations.